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Protein

Peptidylprolyl isomerase

Gene

FKBP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIsomerase, RotamasePROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidylprolyl isomerasePROSITE-ProRule annotation (EC:5.2.1.8PROSITE-ProRule annotation)
Gene namesi
Name:FKBP2Imported
ORF Names:hCG_21364Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000173486.12

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28159

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501430955925 – 142Peptidylprolyl isomeraseSequence analysisAdd BLAST118

Proteomic databases

MaxQBiQ53XJ5
PRIDEiQ53XJ5

Expressioni

Gene expression databases

BgeeiENSG00000173486
ExpressionAtlasiQ53XJ5 baseline and differential

Structurei

3D structure databases

SMRiQ53XJ5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 137PPIase FKBP-typeInterPro annotationAdd BLAST89

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0549 Eukaryota
COG0545 LUCA
HOVERGENiHBG051623
KOiK09569
OMAiGILGMCE
OrthoDBiEOG091G02W1

Family and domain databases

InterProiView protein in InterPro
IPR023566 PPIase_FKBP
IPR001179 PPIase_FKBP_dom
PANTHERiPTHR10516 PTHR10516, 1 hit
PfamiView protein in Pfam
PF00254 FKBP_C, 1 hit
PROSITEiView protein in PROSITE
PS50059 FKBP_PPIASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q53XJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLSWFRVLT VLSICLSAVA TATGAEGKRK LQIGVKKRVD HCPIKSRKGD
60 70 80 90 100
VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE
110 120 130 140
KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL
Length:142
Mass (Da):15,649
Last modified:May 24, 2005 - v1
Checksum:i01024F869BA7B5DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009861 mRNA Translation: AAP88863.1
CR407636 mRNA Translation: CAG28564.1
CH471076 Genomic DNA Translation: EAW74224.1
CH471076 Genomic DNA Translation: EAW74225.1
RefSeqiNP_001128680.1, NM_001135208.1
NP_004461.2, NM_004470.3
NP_476433.1, NM_057092.2
XP_005273905.1, XM_005273848.3
UniGeneiHs.227729

Genome annotation databases

GeneIDi2286
KEGGihsa:2286
UCSCiuc001nyy.4 human

Similar proteinsi

Entry informationi

Entry nameiQ53XJ5_HUMAN
AccessioniPrimary (citable) accession number: Q53XJ5
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 113 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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