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Protein
Submitted name:

FK506 binding protein 2, 13kDa

Gene

FKBP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
FK506 binding protein 2, 13kDaImported
Submitted name:
FK506 binding protein 2, 13kDa, isoform CRA_aImported
Submitted name:
FKBP2 proteinImported
Gene namesi
Name:FKBP2Imported
ORF Names:hCG_21364Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28159.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500878071125 – 142Sequence analysisAdd BLAST118

Expressioni

Gene expression databases

BgeeiENSG00000173486.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000310935.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini49 – 137PPIase FKBP-typeInterPro annotationAdd BLAST89

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG0549. Eukaryota.
COG0545. LUCA.
HOVERGENiHBG051623.
KOiK09569.
OMAiQGLMGMC.
OrthoDBiEOG091G02W1.

Family and domain databases

InterProiIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
PROSITEiPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53XJ5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLSWFRVLT VLSICLSAVA TATGAEGKRK LQIGVKKRVD HCPIKSRKGD
60 70 80 90 100
VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE
110 120 130 140
KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL
Length:142
Mass (Da):15,649
Last modified:May 24, 2005 - v1
Checksum:i01024F869BA7B5DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei142Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009861 mRNA. Translation: AAP88863.1.
CR407636 mRNA. Translation: CAG28564.1.
CH471076 Genomic DNA. Translation: EAW74224.1.
CH471076 Genomic DNA. Translation: EAW74225.1.
RefSeqiNP_001128680.1. NM_001135208.1.
NP_004461.2. NM_004470.3.
NP_476433.1. NM_057092.2.
XP_005273905.1. XM_005273848.3.
UniGeneiHs.227729.

Genome annotation databases

GeneIDi2286.
KEGGihsa:2286.
UCSCiuc001nyy.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT009861 mRNA. Translation: AAP88863.1.
CR407636 mRNA. Translation: CAG28564.1.
CH471076 Genomic DNA. Translation: EAW74224.1.
CH471076 Genomic DNA. Translation: EAW74225.1.
RefSeqiNP_001128680.1. NM_001135208.1.
NP_004461.2. NM_004470.3.
NP_476433.1. NM_057092.2.
XP_005273905.1. XM_005273848.3.
UniGeneiHs.227729.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000310935.

Protocols and materials databases

DNASUi2286.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2286.
KEGGihsa:2286.
UCSCiuc001nyy.4. human.

Organism-specific databases

CTDi2286.
PharmGKBiPA28159.

Phylogenomic databases

eggNOGiKOG0549. Eukaryota.
COG0545. LUCA.
HOVERGENiHBG051623.
KOiK09569.
OMAiQGLMGMC.
OrthoDBiEOG091G02W1.

Miscellaneous databases

ChiTaRSiFKBP2. human.
GenomeRNAii2286.

Gene expression databases

BgeeiENSG00000173486.

Family and domain databases

InterProiIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
PROSITEiPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53XJ5_HUMAN
AccessioniPrimary (citable) accession number: Q53XJ5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.