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Protein
Submitted name:

Full-length cDNA clone CS0DC014YE11 of Neuroblastoma of Homo sapiens (human)

Gene

XRCC3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Full-length cDNA clone CS0DC014YE11 of Neuroblastoma of Homo sapiens (human)Imported
Submitted name:
X-ray repair complementing defective repair in Chinese hamster cells 3Imported
Submitted name:
X-ray repair complementing defective repair in Chinese hamster cells 3, isoform CRA_aImported
Submitted name:
cDNA FLJ12767 fis, clone NT2RP2001536, highly similar to DNA-repair protein XRCC3Imported
Submitted name:
cDNA FLJ13584 fis, clone PLACE1009113, highly similar to DNA-repair protein XRCC3Imported
Submitted name:
cDNA FLJ42507 fis, clone BRACE2040514, highly similar to DNA-repair protein XRCC3Imported
Gene namesi
Name:XRCC3Imported
ORF Names:hCG_25500Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37422.

Expressioni

Gene expression databases

BgeeiENSG00000126215.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000343392.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini78 – 259RECA_2InterPro annotationAdd BLAST182

Phylogenomic databases

eggNOGiKOG1564. Eukaryota.
COG0468. LUCA.
HOVERGENiHBG054179.
KOiK10880.
OMAiLLMRLMV.
OrthoDBiEOG091G0SMJ.

Family and domain databases

CDDicd01123. Rad51_DMC1_radA. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR027417. P-loop_NTPase.
IPR033925. Rad51_DMC1_RadA.
IPR020588. RecA_ATP-bd.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53XC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLDLLDLNP RIIAAIKKAK LKSVKEVLHF SGPDLKRLTN LSSPEVWHLL
60 70 80 90 100
RTASLHLRGS SILTALQLHQ QKERFPTQHQ RLSLGCPVLD ALLRGGLPLD
110 120 130 140 150
GITELAGRSS AGKTQLALQL CLAVQFPRQH GGLEAGAVYI CTEDAFPHKR
160 170 180 190 200
LQQLMAQQPR LRTDVPGELL QKLRFGSQIF IEHVADVDTL LECVNKKVPV
210 220 230 240 250
LLSRGMARLV VIDSVAAPFR CEFDSQASAP RARHLQSLGA TLRELSSAFQ
260 270 280 290 300
SPVLCINQVT EAMEEQGAAH GPLGFWDERV SPALGITWAN QLLVRLLADR
310 320 330 340
LREEEAALGC PARTLRVLSA PHLPPSSCSY TISAEGVRGT PGTQSH
Length:346
Mass (Da):37,850
Last modified:May 24, 2005 - v1
Checksum:i4DDF3B163C3B3332
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007417 mRNA. Translation: AAP36085.1.
AK022829 mRNA. Translation: BAG51121.1.
AK023646 mRNA. Translation: BAG51212.1.
AK124498 mRNA. Translation: BAG54042.1.
BX161398 mRNA. Translation: CAD61884.1.
CH471061 Genomic DNA. Translation: EAW81837.1.
CH471061 Genomic DNA. Translation: EAW81838.1.
CH471061 Genomic DNA. Translation: EAW81839.1.
CH471061 Genomic DNA. Translation: EAW81840.1.
CH471061 Genomic DNA. Translation: EAW81841.1.
CH471061 Genomic DNA. Translation: EAW81842.1.
RefSeqiNP_001093588.1. NM_001100118.1.
NP_001093589.1. NM_001100119.1.
NP_005423.1. NM_005432.3.
XP_005268103.1. XM_005268046.2.
XP_011535440.1. XM_011537138.2.
UniGeneiHs.592325.
Hs.733412.

Genome annotation databases

GeneIDi7517.
KEGGihsa:7517.
UCSCiuc001yny.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007417 mRNA. Translation: AAP36085.1.
AK022829 mRNA. Translation: BAG51121.1.
AK023646 mRNA. Translation: BAG51212.1.
AK124498 mRNA. Translation: BAG54042.1.
BX161398 mRNA. Translation: CAD61884.1.
CH471061 Genomic DNA. Translation: EAW81837.1.
CH471061 Genomic DNA. Translation: EAW81838.1.
CH471061 Genomic DNA. Translation: EAW81839.1.
CH471061 Genomic DNA. Translation: EAW81840.1.
CH471061 Genomic DNA. Translation: EAW81841.1.
CH471061 Genomic DNA. Translation: EAW81842.1.
RefSeqiNP_001093588.1. NM_001100118.1.
NP_001093589.1. NM_001100119.1.
NP_005423.1. NM_005432.3.
XP_005268103.1. XM_005268046.2.
XP_011535440.1. XM_011537138.2.
UniGeneiHs.592325.
Hs.733412.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000343392.

Protocols and materials databases

DNASUi7517.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7517.
KEGGihsa:7517.
UCSCiuc001yny.5. human.

Organism-specific databases

CTDi7517.
PharmGKBiPA37422.

Phylogenomic databases

eggNOGiKOG1564. Eukaryota.
COG0468. LUCA.
HOVERGENiHBG054179.
KOiK10880.
OMAiLLMRLMV.
OrthoDBiEOG091G0SMJ.

Miscellaneous databases

GenomeRNAii7517.

Gene expression databases

BgeeiENSG00000126215.

Family and domain databases

CDDicd01123. Rad51_DMC1_radA. 1 hit.
Gene3Di3.40.50.300. 1 hit.
InterProiIPR013632. DNA_recomb/repair_Rad51_C.
IPR016467. DNA_recomb/repair_RecA-like.
IPR027417. P-loop_NTPase.
IPR033925. Rad51_DMC1_RadA.
IPR020588. RecA_ATP-bd.
[Graphical view]
PfamiPF08423. Rad51. 1 hit.
[Graphical view]
PIRSFiPIRSF005856. Rad51. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
PROSITEiPS50162. RECA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53XC8_HUMAN
AccessioniPrimary (citable) accession number: Q53XC8
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.