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Protein
Submitted name:

Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa

Gene

EIF2B2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factorImported
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Submitted name:
Eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDaImported
Submitted name:
Full-length cDNA clone CS0DI071YM04 of Placenta of Homo sapiens (human)Imported
Gene namesi
Name:EIF2B2Imported
ORF Names:hCG_22350Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000119718.10.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27689.

PTM / Processingi

Proteomic databases

MaxQBiQ53XC2.

Expressioni

Gene expression databases

BgeeiENSG00000119718.
ExpressionAtlasiQ53XC2. baseline and differential.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ53XC2. 3 interactors.

Structurei

3D structure databases

SMRiQ53XC2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-2B alpha/beta/delta subunits family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1465. Eukaryota.
COG1184. LUCA.
HOVERGENiHBG051458.
KOiK03754.
OMAiSNAGELM.
OrthoDBiEOG091G09RO.

Family and domain databases

InterProiView protein in InterPro
IPR000649. IF-2B-related.
PfamiView protein in Pfam
PF01008. IF-2B. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53XC2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGSAAKGSE LSERIESFVE TLKRGGGPRS SEEMARETLG LLRQIITDHR
60 70 80 90 100
WSNAGELMEL IRREGRRMTA AQPSETTVGN MVRRVLKIIR EEYGRLHGRS
110 120 130 140 150
DESDQQESLH KLLTSGGLNE DFSFHYAQLQ SNIIEAINEL LVELEGTMEN
160 170 180 190 200
IAAQALEHIH SNEVIMTIGF SRTVEAFLKE AARKRKFHVI VAECAPFCQG
210 220 230 240 250
HEMAVNLSKA GIETTVMTDA AIFAVMSRVN KVIIGTKTIL ANGALRAVTG
260 270 280 290 300
THTLALAAKH HSTPLIVCAP MFKLSPQFPN EEDSFHKFVA PEEVLPFTEG
310 320 330 340 350
DILEKVSVHC PVFDYVPPEL ITLFISNIGG NAPSYIYRLM SELYHPDDHV

L
Length:351
Mass (Da):38,990
Last modified:May 24, 2005 - v1
Checksum:iC29FE477143F545A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX161473 mRNA. Translation: CAD61929.1.
CH471061 Genomic DNA. Translation: EAW81210.1.
RefSeqiNP_055054.1. NM_014239.3.
UniGeneiHs.409137.

Genome annotation databases

GeneIDi8892.
KEGGihsa:8892.
UCSCiuc001xrc.3. human.

Similar proteinsi

Entry informationi

Entry nameiQ53XC2_HUMAN
AccessioniPrimary (citable) accession number: Q53XC2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 27, 2017
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.