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Protein
Submitted name:

CREB1 protein

Gene

CREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
CREB1 proteinImported
Submitted name:
cAMP responsive element binding protein 1Imported
Submitted name:
cAMP responsive element binding protein 1, isoform CRA_bImported
Submitted name:
cDNA, FLJ96224, Homo sapiens cAMP responsive element binding protein 1 (CREB1),transcript variant A, mRNAImported
Gene namesi
Name:CREB1Imported
ORF Names:hCG_15208Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000118260.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26864

Expressioni

Gene expression databases

BgeeiENSG00000118260

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 146KIDInterPro annotationAdd BLAST60
Domaini269 – 320BZIPInterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili287 – 321Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3584 Eukaryota
ENOG410ZZJZ LUCA
HOGENOMiHOG000007365
HOVERGENiHBG011077

Family and domain databases

InterProiView protein in InterPro
IPR004827 bZIP
IPR003102 Coactivator_CBP_pKID
IPR029802 CREB1
IPR001630 Leuzip_CREB
PANTHERiPTHR22952:SF200 PTHR22952:SF200, 1 hit
PfamiView protein in Pfam
PF00170 bZIP_1, 1 hit
PF02173 pKID, 1 hit
PRINTSiPR00041 LEUZIPPRCREB
SMARTiView protein in SMART
SM00338 BRLZ, 1 hit
PROSITEiView protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit
PS50953 KID, 1 hit

Sequencei

Sequence statusi: Fragment.

Q53X93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA
60 70 80 90 100
PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQIST IAESEDSQES
110 120 130 140 150
VDSVTDSQKR REILSRRPSY RKILNDLSSD APGVPRIEEE KSEEETSAPA
160 170 180 190 200
ITTVTVPTPI YQTSSGQYIA ITQGGAIQLA NNGTDGVQGL QTLTMTNAAA
210 220 230 240 250
TQPGTTILQY AQTTDGQQIL VPSNQVVVQA ASGDVQTYQI RTAPTSTIAP
260 270 280 290 300
GVVMASSPAL PTQPAEEAAR KREVRLMKNR EAARECRRKK KEYVKCLENR
310 320
VAVLENQNKT LIEELKALKD LYCHKSD
Length:327
Mass (Da):35,136
Last modified:May 24, 2005 - v1
Checksum:iF5BA8200EE5184B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei327Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC095407 mRNA Translation: AAH95407.1
AK315226 mRNA Translation: BAG37655.1
CR407617 mRNA Translation: CAG28545.1
CH471063 Genomic DNA Translation: EAW70406.1
CH471063 Genomic DNA Translation: EAW70407.1
CH471063 Genomic DNA Translation: EAW70409.1
RefSeqiNP_004370.1, NM_004379.4
XP_011508949.1, XM_011510647.2
UniGeneiHs.516646
Hs.717136

Genome annotation databases

GeneIDi1385
UCSCiuc002vcd.4 human

Similar proteinsi

Entry informationi

Entry nameiQ53X93_HUMAN
AccessioniPrimary (citable) accession number: Q53X93
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health