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Protein
Submitted name:

CREB1 protein

Gene

CREB1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
CREB1 proteinImported
Submitted name:
cAMP responsive element binding protein 1Imported
Submitted name:
cAMP responsive element binding protein 1, isoform CRA_bImported
Submitted name:
cDNA, FLJ96224, Homo sapiens cAMP responsive element binding protein 1 (CREB1),transcript variant A, mRNAImported
Gene namesi
Name:CREB1Imported
ORF Names:hCG_15208Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26864.

PTM / Processingi

Proteomic databases

MaxQBiQ53X93.

Expressioni

Gene expression databases

BgeeiENSG00000118260.
ExpressionAtlasiQ53X93. baseline and differential.

Structurei

3D structure databases

SMRiQ53X93.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini87 – 146KID (kinase-inducible)InterPro annotationAdd BLAST60
Domaini269 – 320BZIP (basic-leucine zipper)InterPro annotationAdd BLAST52

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili287 – 321Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3584. Eukaryota.
ENOG410ZZJZ. LUCA.
HOGENOMiHOG000007365.
HOVERGENiHBG011077.

Family and domain databases

InterProiView protein in InterPro
IPR004827. bZIP.
IPR003102. Coactivator_CBP_pKID.
IPR001630. Leuzip_CREB.
PfamiView protein in Pfam
PF00170. bZIP_1. 1 hit.
PF02173. pKID. 1 hit.
PRINTSiPR00041. LEUZIPPRCREB.
SMARTiView protein in SMART
SM00338. BRLZ. 1 hit.
PROSITEiView protein in PROSITE
PS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
PS50953. KID. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q53X93-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTMESGAENQ QSGDAAVTEA ENQQMTVQAQ PQIATLAQVS MPAAHATSSA
60 70 80 90 100
PTVTLVQLPN GQTVQVHGVI QAAQPSVIQS PQVQTVQIST IAESEDSQES
110 120 130 140 150
VDSVTDSQKR REILSRRPSY RKILNDLSSD APGVPRIEEE KSEEETSAPA
160 170 180 190 200
ITTVTVPTPI YQTSSGQYIA ITQGGAIQLA NNGTDGVQGL QTLTMTNAAA
210 220 230 240 250
TQPGTTILQY AQTTDGQQIL VPSNQVVVQA ASGDVQTYQI RTAPTSTIAP
260 270 280 290 300
GVVMASSPAL PTQPAEEAAR KREVRLMKNR EAARECRRKK KEYVKCLENR
310 320
VAVLENQNKT LIEELKALKD LYCHKSD
Length:327
Mass (Da):35,136
Last modified:May 24, 2005 - v1
Checksum:iF5BA8200EE5184B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei327Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC095407 mRNA. Translation: AAH95407.1.
AK315226 mRNA. Translation: BAG37655.1.
CR407617 mRNA. Translation: CAG28545.1.
CH471063 Genomic DNA. Translation: EAW70406.1.
CH471063 Genomic DNA. Translation: EAW70407.1.
CH471063 Genomic DNA. Translation: EAW70409.1.
RefSeqiNP_004370.1. NM_004379.4.
XP_011508949.1. XM_011510647.2.
UniGeneiHs.516646.
Hs.717136.

Genome annotation databases

GeneIDi1385.
UCSCiuc002vcd.4. human.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ53X93_HUMAN
AccessioniPrimary (citable) accession number: Q53X93
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.