Unreviewed, UniProtKB/TrEMBL Q53WZ3 (Q53WZ3_MOUSE)

Names and origin

Protein names

Submitted name:
    Ras EMBL AAO46052.1

Gene names

Name:	Kras MGI 96680
Synonyms:	Ki-ras EMBL AAO46052.1, Nras MGI 97376

Organism

Mus musculus (Mouse) EMBL AAO46052.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	37 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Ligand	GTP-binding RuleBase RU003312V0 Spearmint SPM015592 Nucleotide-binding
Gene Ontology (GO)
Biological process	Ras protein signal transduction Inferred from genetic interaction. Source: MGI actin cytoskeleton organization Inferred from genetic interaction. Source: MGI apoptosis Inferred from electronic annotation. Source: Compara cytokine-mediated signaling pathway Inferred from electronic annotation. Source: Compara negative regulation of neuron apoptosis Inferred from genetic interaction. Source: MGI positive regulation of DNA replication Inferred from electronic annotation. Source: Compara positive regulation of MAP kinase activity Inferred from electronic annotation. Source: Compara positive regulation of NF-kappaB transcription factor activity Inferred from electronic annotation. Source: Compara positive regulation of Rac protein signal transduction Inferred from genetic interaction. Source: MGI positive regulation of cell proliferation Inferred from genetic interaction. Source: MGI positive regulation of nitric-oxide synthase activity Inferred from electronic annotation. Source: Compara protein heterooligomerization Inferred from electronic annotation. Source: Compara regulation of long-term neuronal synaptic plasticity Inferred from genetic interaction. Source: MGI regulation of synaptic transmission, GABAergic Inferred from genetic interaction. Source: MGI response to glucocorticoid stimulus Inferred from electronic annotation. Source: Compara response to mineralocorticoid stimulus Inferred from electronic annotation. Source: Compara striated muscle cell differentiation Inferred from genetic interaction. Source: MGI visual learning Inferred from genetic interaction. Source: MGI
Cellular component	membrane fraction Inferred from direct assay. Source: MGI membrane raft Inferred from electronic annotation. Source: Compara plasma membrane Inferred from electronic annotation. Source: Compara
Molecular function	GDP binding Inferred from electronic annotation. Source: Compara GMP binding Inferred from electronic annotation. Source: Compara GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from genetic interaction. Source: MGI LRR domain binding Inferred from electronic annotation. Source: Compara protein C-terminus binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	37	1	EMBL AAO46052.1

Sequences

	Sequence		Length	Mass (Da)
	Q53WZ3-1 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: AAA5B411D73D686A	FASTA	37	4,037
	10 20 30 MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIE

References

[1]	"Parental bias of Ki-ras oncogenes detected in lung tumors from mouse hybrids." You M., Wang Y., Stoner G., You L., Maronpot R., Reynolds S.H., Anderson M. Proc. Natl. Acad. Sci. U.S.A. 89:5804-5808(1992) [PubMed: 1352876] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C3H/HeJ EMBL AAO46052.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	S39586 Genomic DNA. Translation: AAO46052.1.
IPI	IPI00857121.
UniGene	Mm.383182
3D structure databases
SMR	Q53WZ3. Positions 1-37.
ModBase	Search...
Protein-protein interaction databases
STRING	Q53WZ3.
Genome annotation databases
Ensembl	ENSMUST00000026572; ENSMUSP00000026572; ENSMUSG00000025499; Mus musculus. [Genome view] ENSMUST00000029445; ENSMUSP00000029445; ENSMUSG00000027852; Mus musculus. [Genome view] ENSMUST00000032397; ENSMUSP00000032397; ENSMUSG00000030265; Mus musculus. [Genome view] ENSMUST00000032399; ENSMUSP00000032399; ENSMUSG00000030265; Mus musculus. [Genome view] ENSMUST00000093979; ENSMUSP00000091515; ENSMUSG00000025499; Mus musculus. [Genome view] ENSMUST00000097957; ENSMUSP00000095570; ENSMUSG00000025499; Mus musculus. [Genome view] ENSMUST00000111709; ENSMUSP00000107338; ENSMUSG00000030265; Mus musculus. [Genome view] ENSMUST00000111710; ENSMUSP00000107339; ENSMUSG00000030265; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:96680. Kras.
Phylogenomic databases
HOVERGEN	Q53WZ3.
InParanoid	Q53WZ3.
Gene expression databases
ArrayExpress	Q53WZ3.
Bgee	Q53WZ3.
Genevestigator	Q53WZ3.
Family and domain databases
InterPro	IPR013753. Ras. IPR001806. Ras_GTPase. IPR015592. Ras_Ras_related. IPR020849. Ras_small_GTPase. [Graphical view]
PANTHER	PTHR11708:SF125. Ras_Ras_related. 1 hit.
Pfam	PF00071. Ras. 1 hit. [Graphical view]
PRINTS	PR00449. RASTRNSFRMNG.
PROSITE	PS51421. RAS. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q53WZ3_MOUSE

Accession

Primary (citable) accession number: Q53WZ3

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	January 19, 2010
This is version 36 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)