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Protein

Sex-determining region Y protein

Gene

Sry

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi5 – 73HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivatorSAAS annotation, Calmodulin-bindingSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processDifferentiation, Sexual differentiationSAAS annotation, Transcription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Sex-determining region Y proteinSAAS annotation
Gene namesi
Name:SryImported
ORF Names:mCG_8124Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98660. Sry.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000069036.
ExpressionAtlasiQ53WV7. differential.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ53WV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 73HMG boxInterPro annotationAdd BLAST69

Sequence similaritiesi

Belongs to the SRY family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0527. Eukaryota.
ENOG410XT0K. LUCA.
HOVERGENiHBG008712.
KOiK09266.
OMAiQQFHDHH.
OrthoDBiEOG091G0JDD.

Family and domain databases

Gene3Di1.10.30.10. 1 hit.
InterProiView protein in InterPro
IPR009071. HMG_box_dom.
IPR036910. HMG_box_dom_sf.
IPR017253. SRY.
PANTHERiPTHR10270:SF199. PTHR10270:SF199. 5 hits.
PfamiView protein in Pfam
PF00505. HMG_box. 1 hit.
SMARTiView protein in SMART
SM00398. HMG. 1 hit.
SUPFAMiSSF47095. SSF47095. 1 hit.
PROSITEiView protein in PROSITE
PS50118. HMG_BOX_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53WV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGHVKRPMN AFMVWSRGER HKLAQQNPSM QNTEISKQLG CRWKSLTEAE
60 70 80 90 100
KRPFFQEAQR LKILHREKYP NYKYQPHRRA KVSQRSGILQ PAVASTKLYN
110 120 130 140 150
LLQWDRNPHA ITYRQDWSRA AHLYSKNQQS FYWQPVDIPT GHLQQQQQQQ
160 170 180 190 200
QQQQFHNHHQ QQQQFYDHHQ QQQQQQQQQQ QFHDHHQQKQ QFHDHHQQQQ
210 220 230 240 250
QFHDHHHHHQ EQQFHDHHQQ QQQFHDHQQQ QQQQQQQQFH DHHQQKQQFH
260 270 280 290 300
DHHHHQQQQQ FHDHQQQQQQ FHDHQQQQHQ FHDHPQQKQQ FHDHPQQQQQ
310 320 330 340 350
FHDHHHQQQQ KQQFHDHHQQ KQQFHDHHQQ KQQFHDHHQQ QQQFHDHHQQ
360 370 380 390
QQQQQQQQQQ QFHDQQLTYL LTADITGEHT PYQEHLSTAL WLAVS
Length:395
Mass (Da):49,494
Last modified:May 24, 2005 - v1
Checksum:iFFBE9C35161CD80C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U70655 Genomic DNA. Translation: AAC53445.1.
U70656 Genomic DNA. Translation: AAC53446.1.
CH466694 Genomic DNA. Translation: EDL09053.1.
RefSeqiNP_035694.1. NM_011564.1.
UniGeneiMm.377114.

Genome annotation databases

GeneIDi21674.
KEGGimmu:21674.

Similar proteinsi

Entry informationi

Entry nameiQ53WV7_MOUSE
AccessioniPrimary (citable) accession number: Q53WV7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: October 25, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)