Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

S-adenosyl-L-methionine uroporphyrinogen methyltransferase

Gene

TTHB060

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-2083-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
S-adenosyl-L-methionine uroporphyrinogen methyltransferaseImported
Gene namesi
Ordered Locus Names:TTHB060Imported
Encoded oniPlasmid pTT27Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Plasmid pTT27

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VE2X-ray1.80A/B1-235[»]
ProteinModelPortaliQ53WA2.
SMRiQ53WA2. Positions 1-235.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ53WA2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 203200TP_methylaseInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the precorrin methyltransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000290519.
KOiK02303.
OMAiIENEVTH.
OrthoDBiEOG6DRPFR.
PhylomeDBiQ53WA2.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR006366. CobA/CysG_C.
IPR003043. Uropor_MeTrfase_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01469. cobA_cysG_Cterm. 1 hit.
PROSITEiPS00840. SUMT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53WA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGKVYLVGA GFGGPEHLTL KALRVLEVAE VVLHDRLVHP GVLALAKGEL
60 70 80 90 100
VPVGKEGYGG KTPQEAITAR LIALAREGRV VARLKGGDPM VFGRGGEEAL
110 120 130 140 150
ALRRAGIPFE VVPGVTSAVG ALSALGLPLT HRGLARSFAV ATGHDPALPL
160 170 180 190 200
PRADTLVLLM PLHTLGGLKE RLLERFPPET PLALLARVGW PGEAVRLGRV
210 220 230
EDLPGLGEGL PSPALLVVGK VVGLYGELLP KDHGL
Length:235
Mass (Da):24,519
Last modified:May 24, 2005 - v1
Checksum:i00C77E63D086C79D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008227 Genomic DNA. Translation: BAD71856.1.
RefSeqiWP_011174541.1. NC_006462.1.
YP_145299.1. NC_006462.1.

Genome annotation databases

EnsemblBacteriaiBAD71856; BAD71856; BAD71856.
GeneIDi3167889.
KEGGittj:TTHB060.
PATRICi23959046. VBITheThe93045_2004.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008227 Genomic DNA. Translation: BAD71856.1.
RefSeqiWP_011174541.1. NC_006462.1.
YP_145299.1. NC_006462.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VE2X-ray1.80A/B1-235[»]
ProteinModelPortaliQ53WA2.
SMRiQ53WA2. Positions 1-235.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD71856; BAD71856; BAD71856.
GeneIDi3167889.
KEGGittj:TTHB060.
PATRICi23959046. VBITheThe93045_2004.

Phylogenomic databases

HOGENOMiHOG000290519.
KOiK02303.
OMAiIENEVTH.
OrthoDBiEOG6DRPFR.
PhylomeDBiQ53WA2.

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-2083-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ53WA2.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR006366. CobA/CysG_C.
IPR003043. Uropor_MeTrfase_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01469. cobA_cysG_Cterm. 1 hit.
PROSITEiPS00840. SUMT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Crystal Structure of Uroporphyrin-III-C-Methyltrans from Thermus Thermophilus."
    Jeyakanthan J., Tahirov T.H.
    Submitted (MAR-2004) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
  2. "Complete genome sequence of Thermus thermophilus HB8."
    Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB8 / ATCC 27634 / DSM 579Imported.

Entry informationi

Entry nameiQ53WA2_THET8
AccessioniPrimary (citable) accession number: Q53WA2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 6, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, PlasmidImported, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.