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Protein
Submitted name:

S-adenosyl-L-methionine uroporphyrinogen methyltransferase

Gene

TTHB060

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMethyltransferaseUniRule annotationSAAS annotationImported, Transferase
LigandS-adenosyl-L-methionineSAAS annotation

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-2023-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
S-adenosyl-L-methionine uroporphyrinogen methyltransferaseImported
Gene namesi
Ordered Locus Names:TTHB060Imported
Encoded oniPlasmid pTT27Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Plasmid pTT27

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1VE2X-ray1.80A/B1-235[»]
ProteinModelPortaliQ53WA2.
SMRiQ53WA2.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ53WA2.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 203TP_methylaseInterPro annotationAdd BLAST200

Sequence similaritiesi

Belongs to the precorrin methyltransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000290519.
KOiK02303.
OMAiQGVSFIT.
PhylomeDBiQ53WA2.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
InterProiView protein in InterPro
IPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR006366. CobA/CysG_C.
IPR003043. Uropor_MeTrfase_CS.
PfamiView protein in Pfam
PF00590. TP_methylase. 1 hit.
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01469. cobA_cysG_Cterm. 1 hit.
PROSITEiView protein in PROSITE
PS00840. SUMT_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53WA2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGKVYLVGA GFGGPEHLTL KALRVLEVAE VVLHDRLVHP GVLALAKGEL
60 70 80 90 100
VPVGKEGYGG KTPQEAITAR LIALAREGRV VARLKGGDPM VFGRGGEEAL
110 120 130 140 150
ALRRAGIPFE VVPGVTSAVG ALSALGLPLT HRGLARSFAV ATGHDPALPL
160 170 180 190 200
PRADTLVLLM PLHTLGGLKE RLLERFPPET PLALLARVGW PGEAVRLGRV
210 220 230
EDLPGLGEGL PSPALLVVGK VVGLYGELLP KDHGL
Length:235
Mass (Da):24,519
Last modified:May 24, 2005 - v1
Checksum:i00C77E63D086C79D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008227 Genomic DNA. Translation: BAD71856.1.
RefSeqiWP_011174541.1. NC_006462.1.
YP_145299.1. NC_006462.1.

Genome annotation databases

EnsemblBacteriaiBAD71856; BAD71856; BAD71856.
GeneIDi3167889.
KEGGittj:TTHB060.
PATRICifig|300852.9.peg.2004.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ53WA2_THET8
AccessioniPrimary (citable) accession number: Q53WA2
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 5, 2017
This is version 83 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, PlasmidImported, Reference proteomeImported