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Q53W92 (SURE_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
5'-nucleotidase surE
EC=3.1.3.5
Alternative name(s):
Nucleoside 5'-monophosphate phosphohydrolase
Gene names
Name:surE
Ordered Locus Names:TTHB070
Encoded onPlasmid pTT27
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length244 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity. HAMAP MF_00060

Catalytic activity

A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060

Cofactor

Binds 1 divalent metal cation per subunit By similarity.

Subcellular location

Cytoplasm Potential HAMAP MF_00060.

Sequence similarities

Belongs to the surE nucleotidase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
Nucleotide-binding
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Plasmid
Reference proteome
Gene Ontology (GO)
   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function5'-nucleotidase activity

Inferred from electronic annotation. Source: EC

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

nucleotide binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2442445'-nucleotidase surE HAMAP MF_00060
PRO_0000235662

Sites

Metal binding81Divalent metal cation By similarity
Metal binding91Divalent metal cation By similarity
Metal binding391Divalent metal cation By similarity
Metal binding961Divalent metal cation By similarity

Secondary structure

1 ..................................... 244
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q53W92 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 9D45179793B5F5BC

FASTA24426,597
        10         20         30         40         50         60 
MRILVTNDDG IYSPGLWALA EAASQFGEVF VAAPDTEQSA AGHAITIAHP VRAYPHPSPL 

        70         80         90        100        110        120 
HAPHFPAYRV RGTPADCVAL GLHLFGPVDL VLSGVNLGSN LGHEIWHSGT VAAAKQGYLF 

       130        140        150        160        170        180 
GLSAAAFSVP LNGEVPDFAG LRPWLLRTLE TLLRLERPFL VNVNLPLRPK GFLWTRQSVR 

       190        200        210        220        230        240 
AYEGVVIPGE DPMGRPFYWF APRPLKEAEE GTDRWAVAQG FVSATPLRLD LTDETRLQPT 


LAHD

« Hide

References

[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008227 Genomic DNA. Translation: BAD71866.1.
RefSeqYP_145309.1. NC_006462.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2E69X-ray2.20A/B/C/D1-244[»]
2E6BX-ray2.50A/B/C/D1-244[»]
2E6CX-ray2.05A/B/C/D1-244[»]
2E6EX-ray2.50A/B/C/D1-244[»]
2E6GX-ray2.60A/B/C/D/E/F/G/H/I/J/K/L1-244[»]
2E6HX-ray2.10A/B/C/D1-244[»]
ProteinModelPortalQ53W92.
SMRQ53W92. Positions 1-243.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ53W92.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3169602.
GenomeReviewsGene locus TTHB070 in contig AP008227_GR.
KEGGttj:TTHB070.
NMPDRfig|300852.3.peg.2057.
PATRIC23959066. VBITheThe93045_2014.

Phylogenomic databases

eggNOGCOG0496.
HOGENOMHBG600532.
OMAGHEIWHS.
PhylomeDBQ53W92.
ProtClustDBCLSK738894.

Enzyme and pathway databases

BioCycTTHE300852:TTHB070-MONOMER.

Family and domain databases

HAMAPMF_00060. SurE.
[Tree]
InterProIPR002828. SurE-like_Pase/nucleotidase.
[Graphical view]
Gene3DG3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
KOK03787.
PfamPF01975. SurE. 1 hit.
[Graphical view]
SUPFAMSSF64167. SurE-like_Pase/nucleotidase. 1 hit.
TIGRFAMsTIGR00087. SurE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSURE_THET8
AccessionPrimary (citable) accession number: Q53W92
Entry history
Integrated into UniProtKB/Swiss-Prot: May 16, 2006
Last sequence update: May 24, 2005
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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