Q53TQ2 (Q53TQ2_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein TACR1 EMBL AAY14950.1

Gene names

Name:

TACR1 EMBL AAY14950.1

Organism

Homo sapiens (Human) EMBL AAY14950.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	195 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the G-protein coupled receptor 1 family. RuleBase RU000688

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000688
Molecular function	G-protein coupled receptor RuleBase RU000688 Receptor Transducer
Gene Ontology (GO)
Biological_process	acute inflammatory response Inferred from electronic annotation. Source: Compara aggressive behavior Inferred from electronic annotation. Source: Compara angiotensin-mediated drinking behavior Inferred from electronic annotation. Source: Compara associative learning Inferred from electronic annotation. Source: Compara behavioral response to pain Inferred from electronic annotation. Source: Compara eating behavior Inferred from electronic annotation. Source: Compara elevation of cytosolic calcium ion concentration Inferred from electronic annotation. Source: Compara long-term memory Inferred from electronic annotation. Source: Compara operant conditioning Inferred from electronic annotation. Source: Compara positive regulation of action potential Inferred from electronic annotation. Source: Compara positive regulation of blood pressure Inferred from electronic annotation. Source: Compara positive regulation of epithelial cell migration Inferred from electronic annotation. Source: Compara positive regulation of epithelial cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of hormone secretion Inferred from electronic annotation. Source: Compara positive regulation of leukocyte migration Inferred from electronic annotation. Source: Compara positive regulation of lymphocyte proliferation Inferred from electronic annotation. Source: Compara positive regulation of renal sodium excretion Inferred from electronic annotation. Source: Compara positive regulation of saliva secretion Inferred from electronic annotation. Source: Compara positive regulation of stress fiber assembly Inferred from electronic annotation. Source: Compara positive regulation of synaptic transmission, GABAergic Inferred from electronic annotation. Source: Compara positive regulation of synaptic transmission, cholinergic Inferred from electronic annotation. Source: Compara positive regulation of uterine smooth muscle contraction Inferred from electronic annotation. Source: Compara positive regulation of vascular permeability Inferred from electronic annotation. Source: Compara positive regulation of vasoconstriction Inferred from electronic annotation. Source: Compara regulation of smooth muscle cell migration Inferred from electronic annotation. Source: Compara regulation of smooth muscle cell proliferation Inferred from electronic annotation. Source: Compara response to auditory stimulus Inferred from electronic annotation. Source: Compara response to estradiol stimulus Inferred from electronic annotation. Source: Compara response to ethanol Inferred from electronic annotation. Source: Compara response to heat Inferred from electronic annotation. Source: Compara response to morphine Inferred from electronic annotation. Source: Compara response to nicotine Inferred from electronic annotation. Source: Compara response to ozone Inferred from electronic annotation. Source: Compara response to progesterone stimulus Inferred from electronic annotation. Source: Compara smooth muscle contraction involved in micturition Inferred from electronic annotation. Source: Compara sperm ejaculation Inferred from electronic annotation. Source: Compara tachykinin receptor signaling pathway Inferred from electronic annotation. Source: GOC
Cellular_component	cell body Inferred from electronic annotation. Source: Compara cell surface Inferred from electronic annotation. Source: Compara cytoplasm Inferred from electronic annotation. Source: Compara dendrite Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	substance P receptor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	195	1	EMBL AAY14950.1

Sequences

	Sequence		Length	Mass (Da)
	Q53TQ2 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: E67479B08AE41ECE	FASTA	195	22,162
	10 20 30 40 50 60 MDNVLPVDSD LSPNISTNTS EPNQFVQPAW QIVLWAAAYT VIVVTSVVGN VVVMWIILAH 70 80 90 100 110 120 KRMRTVTNYF LVNLAFAEAS MAAFNTVVNF TYAVHNEWYY GLFYCKFHNF FPIAAVFASI 130 140 150 160 170 180 YSMTAVAFDR YMAIIHPLQP RLSATATKVV ICVIWVLALL LAFPQGYYST TETMPSRVVC 190 MIEWPEHPNK IYEKV

References

[1]	"The sequence of Homo sapiens BAC clone RP11-355F16." Rohlfing T., Maupin R., Hawkins M., Davidson T. Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Waterston R.H. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Waterston R. Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Wilson R.K. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007681 Genomic DNA. Translation: AAY14950.1.
IPI	IPI00220633.
UniGene	Hs.633301.
3D structure databases
ProteinModelPortal	Q53TQ2.
ModBase	Search...
Protein-protein interaction databases
STRING	Q53TQ2.
Protein family/group databases
GPCRDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOGENOM	HOG000013018.
HOVERGEN	HBG103412.
Gene expression databases
ArrayExpress	Q53TQ2.
Bgee	Q53TQ2.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR001681. Neurokn_rcpt. IPR000046. NK1_rcpt. [Graphical view]
Pfam	PF00001. 7tm_1. 1 hit. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR01024. NEUROKININ1R. PR00244. NEUROKININR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q53TQ2_HUMAN

Accession

Primary (citable) accession number: Q53TQ2

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.