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Protein
Submitted name:

Putative uncharacterized protein TACR1

Gene

TACR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. substance P receptor activity Source: Ensembl

GO - Biological processi

  1. acute inflammatory response Source: Ensembl
  2. aggressive behavior Source: Ensembl
  3. angiotensin-mediated drinking behavior Source: Ensembl
  4. associative learning Source: Ensembl
  5. behavioral response to pain Source: Ensembl
  6. eating behavior Source: Ensembl
  7. long-term memory Source: Ensembl
  8. operant conditioning Source: Ensembl
  9. positive regulation of action potential Source: Ensembl
  10. positive regulation of blood pressure Source: Ensembl
  11. positive regulation of cytosolic calcium ion concentration Source: Ensembl
  12. positive regulation of epithelial cell migration Source: Ensembl
  13. positive regulation of epithelial cell proliferation Source: Ensembl
  14. positive regulation of hormone secretion Source: Ensembl
  15. positive regulation of leukocyte migration Source: Ensembl
  16. positive regulation of lymphocyte proliferation Source: Ensembl
  17. positive regulation of ossification Source: Ensembl
  18. positive regulation of renal sodium excretion Source: Ensembl
  19. positive regulation of saliva secretion Source: Ensembl
  20. positive regulation of stress fiber assembly Source: Ensembl
  21. positive regulation of synaptic transmission, cholinergic Source: Ensembl
  22. positive regulation of synaptic transmission, GABAergic Source: Ensembl
  23. positive regulation of uterine smooth muscle contraction Source: Ensembl
  24. positive regulation of vascular permeability Source: Ensembl
  25. positive regulation of vasoconstriction Source: Ensembl
  26. regulation of smooth muscle cell migration Source: Ensembl
  27. regulation of smooth muscle cell proliferation Source: Ensembl
  28. response to auditory stimulus Source: Ensembl
  29. response to electrical stimulus Source: Ensembl
  30. response to estradiol Source: Ensembl
  31. response to ethanol Source: Ensembl
  32. response to heat Source: Ensembl
  33. response to morphine Source: Ensembl
  34. response to nicotine Source: Ensembl
  35. response to ozone Source: Ensembl
  36. response to progesterone Source: Ensembl
  37. smooth muscle contraction involved in micturition Source: Ensembl
  38. sperm ejaculation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein TACR1Imported
Gene namesi
Name:TACR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. cell body Source: Ensembl
  2. cell surface Source: Ensembl
  3. cytoplasm Source: Ensembl
  4. dendrite Source: Ensembl
  5. integral component of membrane Source: UniProtKB-KW
  6. plasma membrane Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiQ53TQ2.
ExpressionAtlasiQ53TQ2. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliQ53TQ2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOGENOMiHOG000013018.
HOVERGENiHBG103412.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR000046. NK1_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01024. NEUROKININ1R.
PR00244. NEUROKININR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q53TQ2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDNVLPVDSD LSPNISTNTS EPNQFVQPAW QIVLWAAAYT VIVVTSVVGN
60 70 80 90 100
VVVMWIILAH KRMRTVTNYF LVNLAFAEAS MAAFNTVVNF TYAVHNEWYY
110 120 130 140 150
GLFYCKFHNF FPIAAVFASI YSMTAVAFDR YMAIIHPLQP RLSATATKVV
160 170 180 190
ICVIWVLALL LAFPQGYYST TETMPSRVVC MIEWPEHPNK IYEKV
Length:195
Mass (Da):22,162
Last modified:May 24, 2005 - v1
Checksum:iE67479B08AE41ECE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei195 – 1951Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007681 Genomic DNA. Translation: AAY14950.1.
UniGeneiHs.633301.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007681 Genomic DNA. Translation: AAY14950.1.
UniGeneiHs.633301.

3D structure databases

ProteinModelPortaliQ53TQ2.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ53TQ2.

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOGENOMiHOG000013018.
HOVERGENiHBG103412.

Miscellaneous databases

ChiTaRSiTACR1. human.

Gene expression databases

BgeeiQ53TQ2.
ExpressionAtlasiQ53TQ2. baseline and differential.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR001681. Neurokn_rcpt.
IPR000046. NK1_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01024. NEUROKININ1R.
PR00244. NEUROKININR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The sequence of Homo sapiens BAC clone RP11-355F16."
    Rohlfing T., Maupin R., Hawkins M., Davidson T.
    Submitted (JUN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Waterston R.H.
    Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Waterston R.
    Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Wilson R.K.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ53TQ2_HUMAN
AccessioniPrimary (citable) accession number: Q53TQ2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: January 7, 2015
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.