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Protein
Submitted name:

Cytochrome P450, family 1, subfamily B, polypeptide 1, isoform CRA_a

Gene

CYP1B1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 1, subfamily B, polypeptide 1, isoform CRA_aImported
Submitted name:
cDNA, FLJ93081, Homo sapiens cytochrome P450, family 1, subfamily B, polypeptide 1(CYP1B1), mRNAImported
Gene namesi
Name:CYP1B1Imported
ORF Names:hCG_14819Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27094

Structurei

3D structure databases

SMRiQ53TK1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili519 – 539Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0156 Eukaryota
COG2124 LUCA
HOVERGENiHBG106944
KOiK07410

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR032971 CYP1B1
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PANTHERiPTHR24299:SF2 PTHR24299:SF2, 1 hit
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

Q53TK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTSLSPNDP WPLNPLSIQQ TTLLLLLSVL ATVHVGQRLL RQRRRQLRSA
60 70 80 90 100
PPGPFAWPLI GNAAAVGQAA HLSFARLARR YGDVFQIRLG SCPIVVLNGE
110 120 130 140 150
RAIHQALVQQ GSAFADRPAF ASFRVVSGGR SMAFGHYSEH WKVQRRAAHS
160 170 180 190 200
MMRNFFTRQP RSRQVLEGHV LSEARELVAL LVRGSADGAF LDPRPLTVVA
210 220 230 240 250
VANVMSAVCF GCRYSHDDPE FRELLSHNEE FGRTVGAGSL VDVMPWLQYF
260 270 280 290 300
PNPVRTVFRE FEQLNRNFSN FILDKFLRHC ESLRPGAAPR DMMDAFILSA
310 320 330 340 350
EKKAAGDSHG GGARLDLENV PATITDIFGA SQDTLSTALQ WLLLLFTRYP
360 370 380 390 400
DVQTRVQAEL DQVVGRDRLP CMGDQPNLPY VLAFLYEAMR FSSFVPVTIP
410 420 430 440 450
HATTANTSVL GYHIPKDTVV FVNQWSVNHD PVKWPNPENF DPARFLDKDG
460 470 480 490 500
LINKDLTSRV MIFSVGKRRC IGEELSKMQL FLFISILAHQ CDFRANPNEP
510 520 530 540
AKMNFSYGLT IKPKSFKVNV TLRESMELLD SAVQNLQAKE TCQ
Length:543
Mass (Da):60,832
Last modified:May 24, 2005 - v1
Checksum:i71BB6CA8055122DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK312686 mRNA Translation: BAG35566.1
CH471053 Genomic DNA Translation: EAX00382.1
CH471053 Genomic DNA Translation: EAX00383.1
RefSeqiNP_000095.2, NM_000104.3
UniGeneiHs.154654

Genome annotation databases

GeneIDi1545
KEGGihsa:1545

Similar proteinsi

Entry informationi

Entry nameiQ53TK1_HUMAN
AccessioniPrimary (citable) accession number: Q53TK1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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Main funding by: National Institutes of Health