ID   Q53T87_HUMAN            Unreviewed;       147 AA.
AC   Q53T87;
DT   24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   24-MAY-2005, sequence version 1.
DT   27-MAR-2024, entry version 74.
DE   SubName: Full=Uncharacterized protein TCF7L1 {ECO:0000313|EMBL:AAY15068.1};
DE   Flags: Fragment;
GN   Name=TCF7L1 {ECO:0000313|EMBL:AAY15068.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:AAY15068.1};
RN   [1] {ECO:0000313|EMBL:AAY15068.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Abbott A., Holmes A., Boyer E.;
RT   "The sequence of Homo sapiens BAC clone RP11-312D1.";
RL   Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AAY15068.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Waterston R.H.;
RL   Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:AAY15068.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Waterston R.;
RL   Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AAY15068.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wilson R.K.;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; AC011236; AAY15068.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q53T87; -.
DR   PeptideAtlas; Q53T87; -.
DR   ChiTaRS; TCF7L1; human.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:InterPro.
DR   Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR   InterPro; IPR027397; Catenin-bd_sf.
DR   InterPro; IPR013558; CTNNB1-bd_N.
DR   InterPro; IPR024940; TCF/LEF.
DR   PANTHER; PTHR10373; TRANSCRIPTION FACTOR 7 FAMILY MEMBER; 1.
DR   PANTHER; PTHR10373:SF25; TRANSCRIPTION FACTOR 7-LIKE 1; 1.
DR   Pfam; PF08347; CTNNB1_binding; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125}.
FT   DOMAIN          26..147
FT                   /note="CTNNB1 binding N-teminal"
FT                   /evidence="ECO:0000259|Pfam:PF08347"
FT   REGION          1..102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        79..102
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         147
FT                   /evidence="ECO:0000313|EMBL:AAY15068.1"
SQ   SEQUENCE   147 AA;  15026 MW;  3ACCACFCCA1F6F0A CRC64;
     MPQLGGGGGG GGGGSGGGGG SSAGAAGGGD DLGANDELIP FQDEGGEEQE PSSDSASAQR
     DLDEVKSSLV NESENQSSSS DSEAERRPQP VRDTFQKPRD YFAEVRRPQD SAFFKGPPYP
     GYPFLMIPDL SSPYLSNGPL SPGGART
//