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Q53T87

- Q53T87_HUMAN

UniProt

Q53T87 - Q53T87_HUMAN

Protein
Submitted name:

Putative uncharacterized protein TCF7L1

Gene

TCF7L1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
  1. Functioni

    GO - Molecular functioni

    1. chromatin binding Source: Ensembl
    2. DNA binding Source: Ensembl
    3. sequence-specific DNA binding transcription factor activity Source: Ensembl

    GO - Biological processi

    1. anterior/posterior axis specification, embryo Source: Ensembl
    2. axial mesoderm morphogenesis Source: Ensembl
    3. canonical Wnt signaling pathway Source: InterPro
    4. negative regulation of transcription, DNA-templated Source: Ensembl
    5. positive regulation of transcription from RNA polymerase II promoter during mitosis Source: Ensembl
    6. regulation of stem cell maintenance Source: Ensembl
    7. skin development Source: Ensembl
    8. somatic stem cell maintenance Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized protein TCF7L1Imported
    Gene namesi
    Name:TCF7L1Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. nucleus Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ53T87.
    BgeeiQ53T87.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000419.

    Family and domain databases

    Gene3Di4.10.900.10. 1 hit.
    InterProiIPR027397. Catenin_binding_dom.
    IPR013558. CTNNB1-bd_N.
    IPR024940. TCF/LEF.
    IPR028778. Tcf7l1.
    [Graphical view]
    PANTHERiPTHR10373. PTHR10373. 1 hit.
    PTHR10373:SF25. PTHR10373:SF25. 1 hit.
    PfamiPF08347. CTNNB1_binding. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q53T87-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPQLGGGGGG GGGGSGGGGG SSAGAAGGGD DLGANDELIP FQDEGGEEQE    50
    PSSDSASAQR DLDEVKSSLV NESENQSSSS DSEAERRPQP VRDTFQKPRD 100
    YFAEVRRPQD SAFFKGPPYP GYPFLMIPDL SSPYLSNGPL SPGGART 147
    Length:147
    Mass (Da):15,026
    Last modified:May 24, 2005 - v1
    Checksum:i3ACCACFCCA1F6F0A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei147 – 1471Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011236 Genomic DNA. Translation: AAY15068.1.
    UniGeneiHs.516297.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC011236 Genomic DNA. Translation: AAY15068.1 .
    UniGenei Hs.516297.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG000419.

    Miscellaneous databases

    ChiTaRSi TCF7L1. human.

    Gene expression databases

    ArrayExpressi Q53T87.
    Bgeei Q53T87.

    Family and domain databases

    Gene3Di 4.10.900.10. 1 hit.
    InterProi IPR027397. Catenin_binding_dom.
    IPR013558. CTNNB1-bd_N.
    IPR024940. TCF/LEF.
    IPR028778. Tcf7l1.
    [Graphical view ]
    PANTHERi PTHR10373. PTHR10373. 1 hit.
    PTHR10373:SF25. PTHR10373:SF25. 1 hit.
    Pfami PF08347. CTNNB1_binding. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of Homo sapiens BAC clone RP11-312D1."
      Abbott A., Holmes A., Boyer E.
      Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    2. Waterston R.H.
      Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Waterston R.
      Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
    4. Wilson R.K.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ53T87_HUMAN
    AccessioniPrimary (citable) accession number: Q53T87
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 24, 2005
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.