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Protein
Submitted name:

Putative uncharacterized protein FHL2

Gene

FHL2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. zinc ion binding Source: InterPro

GO - Biological processi

  1. atrial cardiac muscle cell development Source: Ensembl
  2. heart trabecula formation Source: Ensembl
  3. negative regulation of transcription, DNA-templated Source: Ensembl
  4. osteoblast differentiation Source: Ensembl
  5. regulation of transcription from RNA polymerase II promoter Source: Ensembl
  6. ventricular cardiac muscle cell development Source: Ensembl
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein FHL2Imported
Gene namesi
Name:FHL2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. M band Source: Ensembl
  2. nucleus Source: Ensembl
  3. Z disc Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ53T40.

Expressioni

Gene expression databases

BgeeiQ53T40.
ExpressionAtlasiQ53T40. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Contains 3 LIM zinc-binding domains.UniRule annotation

Keywords - Domaini

LIM domainUniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG074526.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiIPR001781. Znf_LIM.
[Graphical view]
PfamiPF00412. LIM. 3 hits.
[Graphical view]
SMARTiSM00132. LIM. 3 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q53T40-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
TRKMEYKGSS WHETCFICHR CQQPIGTKSF IPKDNQNFCV PCYEKQHAMQ
60 70 80 90 100
CVQCKKPITT GGVTYREQPW HKECFVCTAC RKQLSGQRFT ARDDFAYCLN
110 120 130 140 150
CFCDLYAKKC AGCTNPISGL GGTKYISFEE RQWHNDCFNC KKCSLSLVGR
160
GFLTERDDIL CPDCGKDI
Length:168
Mass (Da):19,307
Last modified:May 24, 2005 - v1
Checksum:iFA61C05DC1999ACF
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012360 Genomic DNA. Translation: AAY15012.1.
UniGeneiHs.443687.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC012360 Genomic DNA. Translation: AAY15012.1.
UniGeneiHs.443687.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ53T40.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG074526.

Miscellaneous databases

ChiTaRSiFHL2. human.

Gene expression databases

BgeeiQ53T40.
ExpressionAtlasiQ53T40. baseline and differential.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiIPR001781. Znf_LIM.
[Graphical view]
PfamiPF00412. LIM. 3 hits.
[Graphical view]
SMARTiSM00132. LIM. 3 hits.
[Graphical view]
PROSITEiPS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The sequence of Homo sapiens BAC clone RP11-332H14."
    Haakenson W., Mulvaney E.
    Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Waterston R.H.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Waterston R.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Wilson R.K.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ53T40_HUMAN
AccessioniPrimary (citable) accession number: Q53T40
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: October 29, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.