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Q53SF4

- Q53SF4_HUMAN

UniProt

Q53SF4 - Q53SF4_HUMAN

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Protein
Submitted name:

Putative uncharacterized protein ACVR1

Gene
ACVR1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein predictedi

Functioni

Catalytic activityi

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.SAAS annotations

GO - Molecular functioni

  1. activin receptor activity, type I Source: Ensembl
  2. ATP binding Source: UniProtKB-KW
  3. receptor signaling protein serine/threonine kinase activity Source: Ensembl
  4. transforming growth factor beta receptor activity, type I Source: Ensembl

GO - Biological processi

  1. acute inflammatory response Source: Ensembl
  2. cellular response to glucocorticoid stimulus Source: Ensembl
  3. determination of left/right symmetry Source: Ensembl
  4. gastrulation with mouth forming second Source: Ensembl
  5. germ cell development Source: Ensembl
  6. heart development Source: Ensembl
  7. in utero embryonic development Source: Ensembl
  8. mesoderm formation Source: Ensembl
  9. neural crest cell migration Source: Ensembl
  10. patterning of blood vessels Source: Ensembl
  11. pharyngeal system development Source: Ensembl
  12. regulation of skeletal muscle tissue development Source: Ensembl
  13. smooth muscle cell differentiation Source: Ensembl
  14. transforming growth factor beta receptor signaling pathway Source: Ensembl
  15. urogenital system development Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Kinase, ReceptorSAAS annotations, Serine/threonine-protein kinaseSAAS annotations, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

SignaLinkiQ53SF4.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein ACVR1Imported
Gene namesi
Name:ACVR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. activin receptor complex Source: Ensembl
  2. apical part of cell Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ53SF4.

Expressioni

Gene expression databases

ArrayExpressiQ53SF4.
BgeeiQ53SF4.

Family & Domainsi

Sequence similaritiesi

Contains protein kinase domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG054502.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR000333. TGFB_receptor.
[Graphical view]
PANTHERiPTHR23255. PTHR23255. 1 hit.
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q53SF4-1 [UniParc]FASTAAdd to Basket

« Hide

LAVMHSQSTN QLDVGNNPRV GTKRYMAPEV LDETIQVDCF DSYKRVDIWA    50
FGLVLWEVAR RMVSNGIVED YKPPFYDVVP NDPSFEDMRK VVCVDQQRPN 100
IPNRWFSDPT LTSLAKLMKE CWYQNPSARL TALRIKKTLT KIDNSLDKLK 150
TDC 153
Length:153
Mass (Da):17,701
Last modified:May 24, 2005 - v1
Checksum:iBE38E7E8AE08AA3B
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC019186 Genomic DNA. Translation: AAY15094.1.
UniGeneiHs.470316.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC019186 Genomic DNA. Translation: AAY15094.1 .
UniGenei Hs.470316.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q53SF4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG054502.

Enzyme and pathway databases

SignaLinki Q53SF4.

Gene expression databases

ArrayExpressi Q53SF4.
Bgeei Q53SF4.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR000333. TGFB_receptor.
[Graphical view ]
PANTHERi PTHR23255. PTHR23255. 1 hit.
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The sequence of Homo sapiens BAC clone RP11-301K6."
    Kozlowicz A., Elliott G., Grewal N.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Waterston R.H.
    Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Waterston R.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Wilson R.K.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ53SF4_HUMAN
AccessioniPrimary (citable) accession number: Q53SF4
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 9, 2014
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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