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Protein
Submitted name:

Proliferation-inducing protein 34

Gene

PAP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Proliferation-inducing protein 34Imported
Submitted name:
Proliferation-inducing protein 42Imported
Submitted name:
Putative uncharacterized protein PAPImported
Submitted name:
Regenerating islet-derived 3 alpha, isoform CRA_aImported
Submitted name:
cDNA FLJ76569, highly similar to Homo sapiens regenerating islet-derived 3 alpha (REG3A), transcript variant 1, mRNAImported
Gene namesi
Name:PAPImported
Synonyms:REG3AImported
ORF Names:hCG_39519Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32931.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_500878071027 – 175Sequence analysisAdd BLAST149

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSG00000172016.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000304311.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini47 – 172C-type lectinInterPro annotationAdd BLAST126

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
HOVERGENiHBG004151.
OMAiVKLPYVC.
OrthoDBiEOG091G0MDY.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
[Graphical view]
SMARTiSM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53S56-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPPMALPSV SWMLLSCLML LSQVQGEEPQ RELPSARIRC PKGSKAYGSH
60 70 80 90 100
CYALFLSPKS WTDADLACQK RPSGNLVSVL SGAEGSFVSS LVKSIGNSYS
110 120 130 140 150
YVWIGLHDPT QGTEPNGEGW EWSSSDVMNY FAWERNPSTI SSPGHCASLS
160 170
RSTAFLRWKD YNCNVRLPYV CKFTD
Length:175
Mass (Da):19,395
Last modified:May 24, 2005 - v1
Checksum:iC51149FAC22EB68C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY544128 mRNA. Translation: AAT11159.1.
AY544130 mRNA. Translation: AAT11161.1.
AC069387 Genomic DNA. Translation: AAX93047.1.
AK291973 mRNA. Translation: BAF84662.1.
CH471053 Genomic DNA. Translation: EAW99570.1.
CH471053 Genomic DNA. Translation: EAW99571.1.
CH471053 Genomic DNA. Translation: EAW99572.1.
RefSeqiNP_002571.1. NM_002580.2.
NP_620354.1. NM_138937.2.
NP_620355.1. NM_138938.2.
UniGeneiHs.567312.

Genome annotation databases

GeneIDi5068.
KEGGihsa:5068.
UCSCiuc002sod.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY544128 mRNA. Translation: AAT11159.1.
AY544130 mRNA. Translation: AAT11161.1.
AC069387 Genomic DNA. Translation: AAX93047.1.
AK291973 mRNA. Translation: BAF84662.1.
CH471053 Genomic DNA. Translation: EAW99570.1.
CH471053 Genomic DNA. Translation: EAW99571.1.
CH471053 Genomic DNA. Translation: EAW99572.1.
RefSeqiNP_002571.1. NM_002580.2.
NP_620354.1. NM_138937.2.
NP_620355.1. NM_138938.2.
UniGeneiHs.567312.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000304311.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi5068.
KEGGihsa:5068.
UCSCiuc002sod.3. human.

Organism-specific databases

CTDi5068.
PharmGKBiPA32931.

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
HOVERGENiHBG004151.
OMAiVKLPYVC.
OrthoDBiEOG091G0MDY.

Miscellaneous databases

ChiTaRSiREG3A. human.
GenomeRNAii5068.

Gene expression databases

BgeeiENSG00000172016.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
[Graphical view]
SMARTiSM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53S56_HUMAN
AccessioniPrimary (citable) accession number: Q53S56
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 30, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.