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Protein
Submitted name:

Uncharacterized protein MSH2

Gene

MSH2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized protein MSH2Imported
Gene namesi
Name:MSH2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

PaxDbiQ53RU4.
PeptideAtlasiQ53RU4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini321 – 586MUTSdInterPro annotationAdd BLAST266

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili553 – 576Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0219. Eukaryota.
COG0249. LUCA.
HOGENOMiHOG000196498.
HOVERGENiHBG006399.

Family and domain databases

Gene3Di3.30.420.110. 1 hit.
3.40.1170.10. 1 hit.
InterProiView protein in InterPro
IPR011184. DNA_mismatch_repair_Msh2.
IPR007695. DNA_mismatch_repair_MutS-lik_N.
IPR007861. DNA_mismatch_repair_MutS_clamp.
IPR007696. DNA_mismatch_repair_MutS_core.
IPR016151. DNA_mismatch_repair_MutS_N.
IPR036187. DNA_mismatch_repair_MutS_sf.
IPR007860. DNA_mmatch_repair_MutS_con_dom.
IPR032642. Msh2.
IPR036678. MutS_con_dom_sf.
PANTHERiPTHR11361:SF35. PTHR11361:SF35. 1 hit.
PfamiView protein in Pfam
PF01624. MutS_I. 1 hit.
PF05188. MutS_II. 1 hit.
PF05192. MutS_III. 1 hit.
PF05190. MutS_IV. 1 hit.
PIRSFiPIRSF005813. MSH2. 1 hit.
SMARTiView protein in SMART
SM00533. MUTSd. 1 hit.
SUPFAMiSSF48334. SSF48334. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q53RU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVQPKETLQ LESAAEVGFV RFFQGMPEKP TTTVRLFDRG DFYTAHGEDA
60 70 80 90 100
LLAAREVFKT QGVIKYMGPA GAKNLQSVVL SKMNFESFVK DLLLVRQYRV
110 120 130 140 150
EVYKNRAGNK ASKENDWYLA YKASPGNLSQ FEDILFGNND MSASIGVVGV
160 170 180 190 200
KMSAVDGQRQ VGVGYVDSIQ RKLGLCEFPD NDQFSNLEAL LIQIGPKECV
210 220 230 240 250
LPGGETAGDM GKLRQIIQRG GILITERKKA DFSTKDIYQD LNRLLKGKKG
260 270 280 290 300
EQMNSAVLPE MENQVAVSSL SAVIKFLELL SDDSNFGQFE LTTFDFSQYM
310 320 330 340 350
KLDIAAVRAL NLFQGSVEDT TGSQSLAALL NKCKTPQGQR LVNQWIKQPL
360 370 380 390 400
MDKNRIEERL NLVEAFVEDA ELRQTLQEDL LRRFPDLNRL AKKFQRQAAN
410 420 430 440 450
LQDCYRLYQG INQLPNVIQA LEKHEGKHQK LLLAVFVTPL TDLRSDFSKF
460 470 480 490 500
QEMIETTLDM DQVENHEFLV KPSFDPNLSE LREIMNDLEK KMQSTLISAA
510 520 530 540 550
RDLGLDPGKQ IKLDSSAQFG YYFRVTCKEE KVLRNNKNFS TVDIQKNGVK
560 570 580
FTNSKLTSLN EEYTKNKTEY EEAQDAIVKE IVNISS
Length:586
Mass (Da):66,276
Last modified:May 24, 2005 - v1
Checksum:iE6E1425FBB365120
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei586Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079775 Genomic DNA. Translation: AAY15096.1.
UniGeneiHs.597656.

Similar proteinsi

Entry informationi

Entry nameiQ53RU4_HUMAN
AccessioniPrimary (citable) accession number: Q53RU4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: October 25, 2017
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.