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Protein
Submitted name:

Putative uncharacterized protein STAT4

Gene

STAT4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. sequence-specific DNA binding Source: Ensembl
  2. sequence-specific DNA binding transcription factor activity Source: InterPro
  3. signal transducer activity Source: InterPro

GO - Biological processi

  1. cell proliferation Source: Ensembl
  2. cytokine-mediated signaling pathway Source: Ensembl
  3. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  4. protein phosphorylation Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized protein STAT4Imported
Submitted name:
STAT4Imported
Gene namesi
Name:STAT4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ53RU2.
ExpressionAtlasiQ53RU2. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ53RU2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000261641.

Family and domain databases

Gene3Di1.10.532.10. 1 hit.
InterProiIPR001217. STAT.
IPR029839. STAT4.
IPR013799. STAT_TF_prot_interaction.
[Graphical view]
PANTHERiPTHR11801. PTHR11801. 1 hit.
PTHR11801:SF19. PTHR11801:SF19. 1 hit.
PfamiPF02865. STAT_int. 1 hit.
[Graphical view]
SUPFAMiSSF48092. SSF48092. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q53RU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQWNQVQQL EIKFLEQVDQ FYDDNFPMEI RHLLAQWIEN QDWEAASNNE
60 70 80 90
TMATILLQNL LIQLDEQLGR VSKEKNLLLI HNLKRIRKVL Q
Length:91
Mass (Da):10,962
Last modified:May 24, 2005 - v1
Checksum:i9D34AEB3071B3F3F
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei91 – 911Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079777 Genomic DNA. Translation: AAY15055.1.
EU304788 mRNA. Translation: ACA01857.1.
EU304789 mRNA. Translation: ACA01858.1.
EU304792 mRNA. Translation: ACA01861.1.
EU304793 mRNA. Translation: ACA01862.1.
UniGeneiHs.735572.
Hs.80642.

Genome annotation databases

UCSCiuc010zgl.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC079777 Genomic DNA. Translation: AAY15055.1.
EU304788 mRNA. Translation: ACA01857.1.
EU304789 mRNA. Translation: ACA01858.1.
EU304792 mRNA. Translation: ACA01861.1.
EU304793 mRNA. Translation: ACA01862.1.
UniGeneiHs.735572.
Hs.80642.

3D structure databases

ProteinModelPortaliQ53RU2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc010zgl.2. human.

Phylogenomic databases

HOGENOMiHOG000261641.

Gene expression databases

BgeeiQ53RU2.
ExpressionAtlasiQ53RU2. baseline and differential.

Family and domain databases

Gene3Di1.10.532.10. 1 hit.
InterProiIPR001217. STAT.
IPR029839. STAT4.
IPR013799. STAT_TF_prot_interaction.
[Graphical view]
PANTHERiPTHR11801. PTHR11801. 1 hit.
PTHR11801:SF19. PTHR11801:SF19. 1 hit.
PfamiPF02865. STAT_int. 1 hit.
[Graphical view]
SUPFAMiSSF48092. SSF48092. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The sequence of Homo sapiens BAC clone RP11-317J9."
    Meyer R., VanBrunt A.
    Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. Waterston R.H.
    Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  3. Waterston R.
    Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  4. Wilson R.K.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  5. "Association of STAT4 with human lupus."
    Kozyrev S.V., Abelson A.-K., Alarcon-Riquelme M.E.
    Submitted (NOV-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported, PancreasImported, SpleenImported, TestisImported and UterusImported.

Entry informationi

Entry nameiQ53RU2_HUMAN
AccessioniPrimary (citable) accession number: Q53RU2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: January 7, 2015
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.