Probable linoleate 9S-lipoxygenase 4 - Oryza sativa subsp. japonica (Rice)

Preferred order of sections

Names and origin

Protein names

Recommended name:
Probable linoleate 9S-lipoxygenase 4
EC=1.13.11.58

Alternative name(s):
Lipoxygenase 4

Gene names

Ordered Locus Names:

Os03g0700700, LOC_Os03g49380

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	877 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. Catalyzes the hydroperoxidation of lipids containing a cis,cis-1,4-pentadiene structure By similarity.
Catalytic activity	Linoleate + O₂ = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
Cofactor	Binds 1 iron ion per subunit. Iron is tightly bound By similarity.
Pathway	Lipid metabolism; oxylipin biosynthesis.
Sequence similarities	Belongs to the lipoxygenase family. Contains 1 lipoxygenase domain. Contains 1 PLAT domain.
Sequence caution	The sequence AK072689 differs from that shown. Reason: Frameshift at position 686.

Ontologies

Keywords
Biological process	Fatty acid biosynthesis Lipid synthesis Oxylipin biosynthesis
Ligand	Iron Metal-binding
Molecular function	Dioxygenase Oxidoreductase
Gene Ontology (GO)
Biological process	oxylipin biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	iron ion binding Inferred from electronic annotation. Source: InterPro lipoxygenase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 877

877

Probable linoleate 9S-lipoxygenase 4

PRO_0000220710

Regions

Domain

38 – 165

128

PLAT

Domain

168 – 877

710

Lipoxygenase

Sites

Metal binding

528

1

Iron; catalytic By similarity

Metal binding

533

1

Iron; catalytic By similarity

Metal binding

719

1

Iron; catalytic By similarity

Metal binding

723

1

Iron; catalytic By similarity

Metal binding

877

1

Iron; via carboxylate; catalytic By similarity

Sequences

Sequence

Length

Mass (Da)

Tools

Q53RB0 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 9B4EBB61CDCD9B7C
Show »

FASTA

877

98,698

        10         20         30         40         50         60 
MQVQGFFDRL TGRNKEAWKE GRIRGTAVLV KKDVLGLGDF HASLLDGVHN ILGHKEGVAF 

        70         80         90        100        110        120 
RLVSATARDP SNGGRGKLGK PAHLEELVVT MKSTAAGESV FRVAFEWDES QGIPGAVVVT 

       130        140        150        160        170        180 
NSNRSEFFLK TLTLDGVPGK GTVVFVANSW IYPADNYQYE RVFFANDTYL PSKMPAPLIP 

       190        200        210        220        230        240 
YRQEELNILR GDGKIGPYKE HDRIYRYDYY NDLGQPDKGS KLVRPVLGGS QELPYPRRGR 

       250        260        270        280        290        300 
TGRAPTKTDP NTESRLPLLD LNIYVPRDER FGHLKMSDFL GYSLKAIVEG VLPIIRTYVD 

       310        320        330        340        350        360 
TTPKEFDSFQ DIMELYEGGL KVANASALAE IKKRVPFELI KSLLPVAGDQ VLKLPLPHVI 

       370        380        390        400        410        420 
KEDKFAWRTD EEFAREMLAG VNPVMIKRLT NFPAKSTLDP NVYGDHTSKI TEAHIKHNME 

       430        440        450        460        470        480 
GLTVQNALKG NRLFILDHHD HFMPFLDKIN KLDGNFIYAS RTILLLKDDG TLKPLAIELS 

       490        500        510        520        530        540 
LPHPDGQQHG AVSKVYTPAN TGVESQIWQL AKAYASVNDS AWHQLISHWL NTHAVIEPFV 

       550        560        570        580        590        600 
IATNRQLSVV HPVHKLLSPH YRDTMNINAL ARQTLINADG IFEKTVFPGK YALEMSSVVY 

       610        620        630        640        650        660 
KNWKFTEQAL PVDLVKRGVA VPDPTSPYNV RLLIKDYPYA VDGLVIWWAI ERWVGEYLAI 

       670        680        690        700        710        720 
YYPNDGVLRG DEELQAWWKE VREVGHGDLK DQDWWPKMDT VQELTRACTI IIWIASALHA 

       730        740        750        760        770        780 
AVNFGQYPYA GFLPNRPTVS RRPMPEPGTE EYAKLERGGD EADLVFIHTI TSQFQTILGI 

       790        800        810        820        830        840 
SLIEILSKHS SDEVYLGQRD TPEWTSDAKA LDAFKRFGSR LVDIENRIKD MNGNSALKNR 

       850        860        870 
NGPVKMPYML LYPNTSDVTK EKGQGLTAMG IPNSISI

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References

[1]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[2]	"Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice." The rice full-length cDNA consortium Science 301:376-379(2003) [PubMed: 12869764] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: cv. Nipponbare.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC093017 Genomic DNA. Translation: AAX95641.1. AK072689 mRNA. No translation available.
3D structure databases
ProteinModelPortal	Q53RB0.
SMR	Q53RB0. Positions 21-877.
ModBase	Search...
Protein-protein interaction databases
STRING	Q53RB0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g49380.1; LOC_Os03g49380.1; LOC_Os03g49380.
Organism-specific databases
Gramene	Q53RB0.
Phylogenomic databases
GeneTree	EPGT00070000028239.
OMA	TPKEFDS.
PhylomeDB	Q53RB0.
Family and domain databases
InterPro	IPR008976. Lipase_LipOase. IPR000907. LipOase. IPR013819. LipOase_C. IPR020834. LipOase_CS. IPR020833. LipOase_Fe_BS. IPR001024. LipOase_LH2. IPR001246. LipOase_pln. [Graphical view]
Gene3D	G3DSA:2.60.60.20. Lipase_LipOase. 1 hit.
PANTHER	PTHR11771. LipOase. 1 hit.
Pfam	PF00305. Lipoxygenase. 1 hit. PF01477. PLAT. 1 hit. [Graphical view]
PRINTS	PR00087. LIPOXYGENASE. PR00468. PLTLPOXGNASE.
SMART	SM00308. LH2. 1 hit. [Graphical view]
SUPFAM	SSF49723. Lipase_LipOase. 1 hit. SSF48484. Lipoxygenase. 1 hit.
PROSITE	PS00711. LIPOXYGENASE_1. 1 hit. PS00081. LIPOXYGENASE_2. 1 hit. PS51393. LIPOXYGENASE_3. 1 hit. PS50095. PLAT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

LOX4_ORYSJ

Accession

Primary (citable) accession number: Q53RB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 30, 2005
Last sequence update:	May 24, 2005
Last modified:	December 14, 2011
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program

Relevant documents

Oryza sativa (rice)

Index of Oryza sativa entries and their corresponding gene designations

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Sites

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry information

Relevant documents