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Protein
Submitted name:

cDNA FLJ77882, highly similar to Homo sapiens kruppel-like fetal and embryonic globin gene activator (FKLF) mRNA

Gene

TIEG2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ77882, highly similar to Homo sapiens kruppel-like fetal and embryonic globin gene activator (FKLF) mRNAImported
Gene namesi
Name:TIEG2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000172059.10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA36518

PTM / Processingi

Proteomic databases

MaxQBiQ53QU8

Expressioni

Gene expression databases

BgeeiENSG00000172059
ExpressionAtlasiQ53QU8 baseline and differential

Structurei

3D structure databases

SMRiQ53QU8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini394 – 423C2H2-typeInterPro annotationAdd BLAST30
Domaini424 – 453C2H2-typeInterPro annotationAdd BLAST30
Domaini454 – 481C2H2-typeInterPro annotationAdd BLAST28

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOVERGENiHBG052264
KOiK09209
OMAiSCQPCLH
OrthoDBiEOG091G1BN0

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SMARTiView protein in SMART
SM00355 ZnF_C2H2, 3 hits
SUPFAMiSSF57667 SSF57667, 2 hits
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 3 hits
PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequencei

Sequence statusi: Complete.

Q53QU8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTPDFAGPD DARAVDIMDI CESILERKRH DSERSTCSIL EQTDMEAVEA
60 70 80 90 100
LVCMSSWGQR SQKGDLLRIR PLTPVSDSGD VTTTVHMDAA TPELPKDFHS
110 120 130 140 150
LSTLCITPPQ SPDLVEPSTR TPVSPQVTDS KACTATDVLQ SSAVVARALS
160 170 180 190 200
GGAERGLLGL EPVPSSPCRA KGTSVIRHTG ESPAACFPTI QTPDCRLSDS
210 220 230 240 250
REGEEQLLGH FETLQDTHLT DSLLSTNLVS CQPCLHKSGG LLLTDKGQQA
260 270 280 290 300
GWPGAVQTCS PKNYENDLPR KTTPLISVSV PAPPVLCQMI PVTGQSSMLP
310 320 330 340 350
AFLKPPPQLS VGTVRPILAQ AAPAPQPVFV GPAVPQGAVM LVLPQGALPP
360 370 380 390 400
PAPCAANVMA AGNTKLLPLA PAPVFITSSQ NCVPQVDFSR RRNYVCSFPG
410 420 430 440 450
CRKTYFKSSH LKAHLRTHTG EKPFNCSWDG CDKKFARSDE LSRHRRTHTG
460 470 480 490 500
EKKFVCPVCD RRFMRSDHLT KHARRHMTTK KIPGWQAEVG KLNRIASAES
510
PGSPLVSMPA SA
Length:512
Mass (Da):55,139
Last modified:May 24, 2005 - v1
Checksum:iA69863B5467FB068
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC104794 Genomic DNA Translation: AAX93098.1
AK289816 mRNA Translation: BAF82505.1
RefSeqiNP_003588.1, NM_003597.4
UniGeneiHs.12229

Genome annotation databases

GeneIDi8462
KEGGihsa:8462
UCSCiuc002raf.1 human

Similar proteinsi

Entry informationi

Entry nameiQ53QU8_HUMAN
AccessioniPrimary (citable) accession number: Q53QU8
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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