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Protein

Probable protein phosphatase 2C 74

Gene

Os11g0242200

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi170 – 1701Manganese 1By similarity
Metal bindingi170 – 1701Manganese 2By similarity
Metal bindingi171 – 1711Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi343 – 3431Manganese 2By similarity
Metal bindingi382 – 3821Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: InterPro

GO - Biological processi

  1. protein dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 74 (EC:3.1.3.16)
Short name:
OsPP2C74
Gene namesi
Ordered Locus Names:Os11g0242200, LOC_Os11g13820
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 11

Organism-specific databases

GrameneiQ53Q11.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 397397Probable protein phosphatase 2C 74PRO_0000363321Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ53Q11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini132 – 384253PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiQ53Q11.
OMAiITHKIEG.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53Q11-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACMLCCSPL PALSSPATGG AAVVGFSSSS RRKAAHVHPA VAVKDHDLSS
60 70 80 90 100
SSPAACGDEG GGAVVIEEEA HPSMMMSVAA PAMKKKAVAA RWRPPRLVVP
110 120 130 140 150
AVAGADEAMA AAAAVKAAKE KEEEEAMEVE GEGFWVASRR GLRHAMEDGY
160 170 180 190 200
GVITHKIEGH SQMAFYGVYD GHGGRAAVDF VAGRLGNNVV AAAEKQRLSE
210 220 230 240 250
KASSPAAADH VAAAIRAAYL ATDSEFLSQG TRGGACAATA LVIDGDLYVA
260 270 280 290 300
NLGDCRAVIS RHGAAAALTS DHTPARDDER SRIESSGGYV SCGSNGVWRV
310 320 330 340 350
QDCLAVTRSF GDGGLKRWVV AEPEVSRTPL AGAGCEFLVI ASDGLWNKVS
360 370 380 390
NQEAVDAVAA GHYSVDSCRR LVDMARRRGS RDDVTVMVVD LKRFLNC
Length:397
Mass (Da):41,352
Last modified:May 24, 2005 - v1
Checksum:i044256CA639D0042
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC119671 Genomic DNA. Translation: AAX95399.1.
DP000010 Genomic DNA. Translation: ABA92329.1.
RefSeqiNP_001176453.1. NM_001189524.1.
UniGeneiOs.98987.

Genome annotation databases

GeneIDi9267539.
KEGGiosa:9267539.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC119671 Genomic DNA. Translation: AAX95399.1.
DP000010 Genomic DNA. Translation: ABA92329.1.
RefSeqiNP_001176453.1. NM_001189524.1.
UniGeneiOs.98987.

3D structure databases

ProteinModelPortaliQ53Q11.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9267539.
KEGGiosa:9267539.

Organism-specific databases

GrameneiQ53Q11.

Phylogenomic databases

eggNOGiCOG0631.
InParanoidiQ53Q11.
OMAiITHKIEG.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C74_ORYSJ
AccessioniPrimary (citable) accession number: Q53Q11
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 10, 2009
Last sequence update: May 24, 2005
Last modified: January 7, 2015
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.