Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q53N72

- MPK15_ORYSJ

UniProt

Q53N72 - MPK15_ORYSJ

Protein

Mitogen-activated protein kinase 15

Gene

MPK15

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 1 (24 May 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Enzyme regulationi

    Activated by threonine and tyrosine phosphorylation.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei42 – 421ATPPROSITE-ProRule annotation
    Active sitei139 – 1391Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 279ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. MAP kinase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Mitogen-activated protein kinase 15 (EC:2.7.11.24)
    Short name:
    MAP kinase 15
    Gene namesi
    Name:MPK15
    Ordered Locus Names:Os11g0271100, LOC_Os11g17080
    OrganismiOryza sativa subsp. japonica (Rice)
    Taxonomic identifieri39947 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
    ProteomesiUP000000763: Chromosome 11

    Organism-specific databases

    GrameneiQ53N72.

    Subcellular locationi

    GO - Cellular componenti

    1. plasma membrane Source: EnsemblPlants/Gramene
    2. vacuole Source: EnsemblPlants/Gramene

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 498498Mitogen-activated protein kinase 15PRO_0000239758Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei175 – 1751PhosphothreonineBy similarity
    Modified residuei177 – 1771PhosphotyrosineBy similarity

    Post-translational modificationi

    Dually phosphorylated on Thr-175 and Tyr-177, which activates the enzyme.By similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PRIDEiQ53N72.

    Expressioni

    Inductioni

    By jasmonic acid (JA) and infection with rice blast fungus (M.grisea).1 Publication

    Structurei

    3D structure databases

    ProteinModelPortaliQ53N72.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini13 – 304292Protein kinasePROSITE-ProRule annotationAdd
    BLAST

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi175 – 1773TXY

    Domaini

    The TXY motif contains the threonine and tyrosine residues whose phosphorylation activates the MAP kinases.

    Sequence similaritiesi

    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    OMAiMRKKKPI.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00220. S_TKc. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q53N72-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDFFTEYGEG NRYKIEEVIG KGSYGVVCSA LDTHTGEKVA IKKINDIFEH    50
    VSDATRILRE IKLLRLLRHP DIVEIKHILL PPSRREFKDI YVVFELMESD 100
    LHQVIKANDD LTPEHYQFFL YQLLRGLKYI HTANVFHRDL KPKNILANAD 150
    CKLKICDFGL ARVAFSDTPT AIFWTDYVAT RWYRAPELCG SFFSKYTPAI 200
    DIWSIGCIFA ELLTGKPLFP GKNVVHQLDI ITDLLGTPST EAISRIRNEK 250
    ARRYLSSMRR KKPIPFTQKF PNADPLALRL LERMLSFEPK DRPNAEEALA 300
    DPYFRNIANV DREPSAQPVT KLEFEFERRR ITKEDIRELI YRDILEYHPN 350
    MLREYLEGTE SAGFMYPSAV DHFKKQFAYL EEHYAKGSTA APPERQHNSL 400
    PRPSVLYSDD RPQNTANIAE DLSKCVLGDN TQKMHQGSAS VCANRVPQGG 450
    AARPGKVVGS ALRYGNCSTS TAEQYEHRRT DRNPALATNT VSPRGSYP 498
    Length:498
    Mass (Da):56,967
    Last modified:May 24, 2005 - v1
    Checksum:iEBC9F67E62DF299D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC135497 Genomic DNA. Translation: AAX94956.1.
    DP000010 Genomic DNA. Translation: ABA92667.1.
    AK068981 mRNA. No translation available.

    Genome annotation databases

    EnsemblPlantsiOS11T0271100-01; OS11T0271100-01; OS11G0271100.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC135497 Genomic DNA. Translation: AAX94956.1 .
    DP000010 Genomic DNA. Translation: ABA92667.1 .
    AK068981 mRNA. No translation available.

    3D structure databases

    ProteinModelPortali Q53N72.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q53N72.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi OS11T0271100-01 ; OS11T0271100-01 ; OS11G0271100 .

    Organism-specific databases

    Gramenei Q53N72.

    Phylogenomic databases

    eggNOGi COG0515.
    OMAi MRKKKPI.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR003527. MAP_kinase_CS.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR002290. Ser/Thr_dual-sp_kinase_dom.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00220. S_TKc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS01351. MAPK. 1 hit.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
      The rice chromosomes 11 and 12 sequencing consortia
      BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Nipponbare.
    2. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
      The rice full-length cDNA consortium
      Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Nipponbare.
    3. "Molecular analysis of the rice MAP kinase gene family in relation to Magnaporthe grisea infection."
      Reyna N.S., Yang Y.
      Mol. Plant Microbe Interact. 19:530-540(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION, NOMENCLATURE.

    Entry informationi

    Entry nameiMPK15_ORYSJ
    AccessioniPrimary (citable) accession number: Q53N72
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 13, 2006
    Last sequence update: May 24, 2005
    Last modified: October 1, 2014
    This is version 65 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Oryza sativa (rice)
      Index of Oryza sativa entries and their corresponding gene designations
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3