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Q53LU4

- LAC18_ORYSJ

UniProt

Q53LU4 - LAC18_ORYSJ

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Protein

Laccase-18

Gene

LAC18

Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Lignin degradation and detoxification of lignin-derived products.By similarity

Catalytic activityi

4 benzenediol + O2 = 4 benzosemiquinone + 2 H2O.

Cofactori

Binds 4 copper ions per monomer.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi87 – 871Copper 1By similarity
Metal bindingi89 – 891Copper 2By similarity
Metal bindingi132 – 1321Copper 2By similarity
Metal bindingi134 – 1341Copper 3By similarity
Metal bindingi488 – 4881Copper 4Sequence Analysis
Metal bindingi491 – 4911Copper 1By similarity
Metal bindingi493 – 4931Copper 3By similarity
Metal bindingi550 – 5501Copper 3By similarity
Metal bindingi551 – 5511Copper 4Sequence Analysis
Metal bindingi552 – 5521Copper 2By similarity
Metal bindingi556 – 5561Copper 4Sequence Analysis
Metal bindingi561 – 5611Copper 4Sequence Analysis

GO - Molecular functioni

  1. copper ion binding Source: InterPro
  2. hydroquinone:oxygen oxidoreductase activity Source: UniProtKB-EC

GO - Biological processi

  1. lignin catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Lignin degradation

Keywords - Ligandi

Copper, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Laccase-18 (EC:1.10.3.2)
Alternative name(s):
Benzenediol:oxygen oxidoreductase 18
Diphenol oxidase 18
Urishiol oxidase 18
Gene namesi
Name:LAC18
Ordered Locus Names:Os11g0264000, LOC_Os11g16260
ORF Names:OsJ_032226
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 11

Organism-specific databases

GrameneiQ53LU4.

Subcellular locationi

GO - Cellular componenti

  1. apoplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Apoplast, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929Sequence AnalysisAdd
BLAST
Chaini30 – 595566Laccase-18PRO_0000291903Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi42 – 421N-linked (GlcNAc...)Sequence Analysis
Glycosylationi48 – 481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi121 – 1211N-linked (GlcNAc...)Sequence Analysis
Glycosylationi206 – 2061N-linked (GlcNAc...)Sequence Analysis
Glycosylationi345 – 3451N-linked (GlcNAc...)Sequence Analysis
Glycosylationi382 – 3821N-linked (GlcNAc...)Sequence Analysis
Glycosylationi402 – 4021N-linked (GlcNAc...)Sequence Analysis
Glycosylationi409 – 4091N-linked (GlcNAc...)Sequence Analysis
Glycosylationi439 – 4391N-linked (GlcNAc...)Sequence Analysis
Glycosylationi470 – 4701N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ53LU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 153117Plastocyanin-like 1Add
BLAST
Domaini162 – 316155Plastocyanin-like 2Add
BLAST
Domaini429 – 571143Plastocyanin-like 3Add
BLAST

Sequence similaritiesi

Belongs to the multicopper oxidase family.Curated
Contains 3 plastocyanin-like domains.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG2132.
InParanoidiQ53LU4.
OMAiNDINGTE.

Family and domain databases

Gene3Di2.60.40.420. 4 hits.
InterProiIPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view]
PfamiPF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view]
SUPFAMiSSF49503. SSF49503. 4 hits.
TIGRFAMsiTIGR03389. laccase. 1 hit.
PROSITEiPS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q53LU4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEKLSTAASL FCVVVAATAL AMAVVGGEAA VVEQTFMVHE MNVTHLCNTT
60 70 80 90 100
KIYVVNGRFP GPTVDVTEGD TVVVHVINRL PHGLTIHWHG VRQMRSCWAD
110 120 130 140 150
GAGYVTECPI HPGGEKTYRF NVTGQVGTLW WHAHVTCLRA TINGAFIIRP
160 170 180 190 200
RNGKYPFLTP AKDVPIIIGE WWELDLIELD RRMLDGNFDD NPLSATINGK
210 220 230 240 250
LGDLSNCSST VEESFVLDVK RGESYLLRVI NTALFSEYYF KVAGHTFTVV
260 270 280 290 300
GADGNYLTPY KTDMVTVAPG EAIDVLMFTD APPAYYHMVA LANQPPPPDL
310 320 330 340 350
QIPQLTSRGL IRYAGAAMDS NNLPMPMPVM PDQHNTMPSY YFRRNLTGLA
360 370 380 390 400
LPEQQQRHRV PAHVDERLLI TLGLGSICRG GNTTTCKRGR SPETVVVATM
410 420 430 440 450
NNVSFHHTNA TALLEHYYDG RPEGVYTEDF PVRPPRPFNY TDRELIPAGP
460 470 480 490 500
LEAALEPTAK AMRLRRFRYN ASVEIVFQST TLLQSDSNPM HLHGYDVFVL
510 520 530 540 550
AQGLGNFDPK RDVEKFNYHN PQLRNTVQVP RGGWAAVRFL ADNPGMWYLH
560 570 580 590
CHFEFHIIMG MATAFIVEDG PTPETSLPPP PPEFKRCGTN GLSQP
Length:595
Mass (Da):66,189
Last modified:May 24, 2005 - v1
Checksum:iED20952A25B72CAF
GO

Sequence cautioni

The sequence BAF28013.2 differs from that shown. Reason: Erroneous gene model prediction.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC138197 Genomic DNA. Translation: AAX96096.1.
DP000010 Genomic DNA. Translation: ABA92481.1.
AP008217 Genomic DNA. Translation: BAF28013.2. Sequence problems.
CM000148 Genomic DNA. Translation: EAZ18017.1.
RefSeqiNP_001067650.2. NM_001074182.2.
UniGeneiOs.86101.

Genome annotation databases

EnsemblPlantsiOS11T0264000-00; OS11T0264000-00; OS11G0264000.
GeneIDi4350236.
KEGGiosa:4350236.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC138197 Genomic DNA. Translation: AAX96096.1 .
DP000010 Genomic DNA. Translation: ABA92481.1 .
AP008217 Genomic DNA. Translation: BAF28013.2 . Sequence problems.
CM000148 Genomic DNA. Translation: EAZ18017.1 .
RefSeqi NP_001067650.2. NM_001074182.2.
UniGenei Os.86101.

3D structure databases

ProteinModelPortali Q53LU4.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS11T0264000-00 ; OS11T0264000-00 ; OS11G0264000 .
GeneIDi 4350236.
KEGGi osa:4350236.

Organism-specific databases

Gramenei Q53LU4.

Phylogenomic databases

eggNOGi COG2132.
InParanoidi Q53LU4.
OMAi NDINGTE.

Family and domain databases

Gene3Di 2.60.40.420. 4 hits.
InterProi IPR001117. Cu-oxidase.
IPR011706. Cu-oxidase_2.
IPR011707. Cu-oxidase_3.
IPR002355. Cu_oxidase_Cu_BS.
IPR008972. Cupredoxin.
IPR017761. Laccase.
[Graphical view ]
Pfami PF00394. Cu-oxidase. 1 hit.
PF07731. Cu-oxidase_2. 1 hit.
PF07732. Cu-oxidase_3. 1 hit.
[Graphical view ]
SUPFAMi SSF49503. SSF49503. 4 hits.
TIGRFAMsi TIGR03389. laccase. 1 hit.
PROSITEi PS00079. MULTICOPPER_OXIDASE1. 1 hit.
PS00080. MULTICOPPER_OXIDASE2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  3. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  4. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.

Entry informationi

Entry nameiLAC18_ORYSJ
AccessioniPrimary (citable) accession number: Q53LU4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: May 24, 2005
Last modified: October 29, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3