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Q53LQ0

- PDI11_ORYSJ

UniProt

Q53LQ0 - PDI11_ORYSJ

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Protein
Protein disulfide isomerase-like 1-1
Gene
PDIL1-1, Os11g0199200, LOC_Os11g09280, OsJ_33281
Organism
Oryza sativa subsp. japonica (Rice)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Probable protein disulfide isomerase that plays an essential role in the segregation of proglutelin and prolamin polypeptides within the ER lumen of endosperm. Required to retain proglutelin in the cisternal ER lumen until ER export and, thereby, indirectly prevents heterotypic interactions with prolamin polypeptides.2 Publications

Catalytic activityi

Catalyzes the rearrangement of -S-S- bonds in proteins.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei69 – 691Nucleophile By similarity
Sitei70 – 701Contributes to redox potential value By similarity
Sitei71 – 711Contributes to redox potential value By similarity
Active sitei72 – 721Nucleophile By similarity
Sitei137 – 1371Lowers pKa of C-terminal Cys of first active site By similarity
Active sitei414 – 4141Nucleophile By similarity
Sitei415 – 4151Contributes to redox potential value By similarity
Sitei416 – 4161Contributes to redox potential value By similarity
Active sitei417 – 4171Nucleophile By similarity
Sitei477 – 4771Lowers pKa of C-terminal Cys of second active site By similarity

GO - Molecular functioni

  1. protein disulfide isomerase activity Source: RefGenome

GO - Biological processi

  1. cell redox homeostasis Source: InterPro
  2. embryo development Source: EnsemblPlants/Gramene
  3. protein folding in endoplasmic reticulum Source: UniProtKB
  4. regulation of programmed cell death Source: EnsemblPlants/Gramene
  5. response to cadmium ion Source: EnsemblPlants/Gramene
  6. response to endoplasmic reticulum stress Source: RefGenome
  7. response to salt stress Source: EnsemblPlants/Gramene
  8. response to zinc ion Source: EnsemblPlants/Gramene
  9. seed development Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Names & Taxonomyi

Protein namesi
Recommended name:
Protein disulfide isomerase-like 1-1 (EC:5.3.4.1)
Short name:
OsPDIL1-1
Alternative name(s):
Endosperm storage protein 2
Short name:
Protein ESP2
Gene namesi
Name:PDIL1-1
Ordered Locus Names:Os11g0199200, LOC_Os11g09280
ORF Names:OsJ_33281
OrganismiOryza sativa subsp. japonica (Rice)
Taxonomic identifieri39947 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBEP cladeEhrhartoideaeOryzeaeOryza
ProteomesiUP000000763: Chromosome 11

Organism-specific databases

GrameneiQ53LQ0.

Subcellular locationi

Endoplasmic reticulum lumen 1 Publication

GO - Cellular componenti

  1. Golgi apparatus Source: EnsemblPlants/Gramene
  2. chloroplast Source: EnsemblPlants/Gramene
  3. endoplasmic reticulum lumen Source: UniProtKB
  4. lytic vacuole within protein storage vacuole Source: EnsemblPlants/Gramene
  5. plant-type cell wall Source: EnsemblPlants/Gramene
  6. plasma membrane Source: EnsemblPlants/Gramene
  7. thylakoid Source: EnsemblPlants/Gramene
  8. vacuolar membrane Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

Pathology & Biotechi

Disruption phenotypei

Accumulation of large quantities of glutelin precursor (proglutelin) in the endosperm.2 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525 Reviewed prediction
Add
BLAST
Chaini26 – 512487Protein disulfide isomerase-like 1-1
PRO_0000400028Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi69 ↔ 72Redox-active By similarity
Glycosylationi285 – 2851N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi414 ↔ 417Redox-active By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ53LQ0.
PRIDEiQ53LQ0.

Expressioni

Developmental stagei

Expressed in developing seeds from 3 to 9 days after anthesis.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ53LQ0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 151120Thioredoxin 1
Add
BLAST
Domaini372 – 491120Thioredoxin 2
Add
BLAST

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi509 – 5124Prevents secretion from ER By similarity

Sequence similaritiesi

Contains 2 thioredoxin domains.

Keywords - Domaini

Redox-active center, Repeat, Signal

Phylogenomic databases

eggNOGiCOG0526.
KOiK09580.
OMAiPEANEEP.

Family and domain databases

Gene3Di3.40.30.10. 3 hits.
InterProiIPR005788. Disulphide_isomerase.
IPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view]
PfamiPF00085. Thioredoxin. 2 hits.
[Graphical view]
SUPFAMiSSF52833. SSF52833. 4 hits.
TIGRFAMsiTIGR01130. ER_PDI_fam. 1 hit.
TIGR01126. pdi_dom. 2 hits.
PROSITEiPS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q53LQ0-1 [UniParc]FASTAAdd to Basket

« Hide

MAISKAWISL LLALAVVLSA PAARAEEAAA AEEGGDAAAE AVLTLDADGF    50
DEAVAKHPFM VVEFYAPWCG HCKKLAPEYE KAAQELSKHD PPIVLAKVDA 100
NDEKNKPLAT KYEIQGFPTL KIFRNQGKNI QEYKGPREAE GIVEYLKKQV 150
GPASKEIKSP EDATNLIDDK KIYIVGIFSE LSGTEYTNFI EVAEKLRSDY 200
DFGHTLHANH LPRGDAAVER PLVRLFKPFD ELVVDSKDFD VTALEKFIDA 250
SSTPKVVTFD KNPDNHPYLL KFFQSSAAKA MLFLNFSTGP FESFKSVYYG 300
AAEEFKDKEI KFLIGDIEAS QGAFQYFGLR EDQVPLIIIQ DGESKKFLKA 350
HVEPDQIVSW LKEYFDGKLS PFRKSEPIPE VNDEPVKVVV ADNVHDFVFK 400
SGKNVLVEFY APWCGHCKKL APILDEAATT LKSDKDVVIA KMDATANDVP 450
SEFDVQGYPT LYFVTPSGKM VPYESGRTAD EIVDFIKKNK ETAGQAKEKA 500
ESAPAEPLKD EL 512
Length:512
Mass (Da):56,855
Last modified:May 24, 2005 - v1
Checksum:i60CA68E115728496
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti435 – 4351K → E in AAX85991. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB373950 mRNA. Translation: BAG50157.1.
AY987391 mRNA. Translation: AAX85991.1.
AC139170 Genomic DNA. Translation: AAX96742.1.
DP000010 Genomic DNA. Translation: ABA91939.1.
AP008217 Genomic DNA. Translation: BAF27799.1.
CM000148 Genomic DNA. Translation: EAZ17736.1.
AK068268 mRNA. Translation: BAG90833.1.
RefSeqiNP_001067436.1. NM_001073968.1.
UniGeneiOs.10985.

Genome annotation databases

EnsemblPlantsiOS11T0199200-01; OS11T0199200-01; OS11G0199200.
GeneIDi4350002.
KEGGiosa:4350002.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB373950 mRNA. Translation: BAG50157.1 .
AY987391 mRNA. Translation: AAX85991.1 .
AC139170 Genomic DNA. Translation: AAX96742.1 .
DP000010 Genomic DNA. Translation: ABA91939.1 .
AP008217 Genomic DNA. Translation: BAF27799.1 .
CM000148 Genomic DNA. Translation: EAZ17736.1 .
AK068268 mRNA. Translation: BAG90833.1 .
RefSeqi NP_001067436.1. NM_001073968.1.
UniGenei Os.10985.

3D structure databases

ProteinModelPortali Q53LQ0.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PaxDbi Q53LQ0.
PRIDEi Q53LQ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi OS11T0199200-01 ; OS11T0199200-01 ; OS11G0199200 .
GeneIDi 4350002.
KEGGi osa:4350002.

Organism-specific databases

Gramenei Q53LQ0.

Phylogenomic databases

eggNOGi COG0526.
KOi K09580.
OMAi PEANEEP.

Family and domain databases

Gene3Di 3.40.30.10. 3 hits.
InterProi IPR005788. Disulphide_isomerase.
IPR005792. Prot_disulphide_isomerase.
IPR012336. Thioredoxin-like_fold.
IPR017937. Thioredoxin_CS.
IPR013766. Thioredoxin_domain.
[Graphical view ]
Pfami PF00085. Thioredoxin. 2 hits.
[Graphical view ]
SUPFAMi SSF52833. SSF52833. 4 hits.
TIGRFAMsi TIGR01130. ER_PDI_fam. 1 hit.
TIGR01126. pdi_dom. 2 hits.
PROSITEi PS00014. ER_TARGET. 1 hit.
PS00194. THIOREDOXIN_1. 2 hits.
PS51352. THIOREDOXIN_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Protein disulfide isomerase like 1-1 participates in the maturation of proglutelin within the endoplasmic reticulum in rice endosperm."
    Satoh-Cruz M., Crofts A.J., Takemoto-Kuno Y., Sugino A., Washida H., Crofts N., Okita T.W., Ogawa M., Satoh H., Kumamaru T.
    Plant Cell Physiol. 51:1581-1593(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, DISRUPTION PHENOTYPE.
  2. "Cloning and characterization of the protein disulfide isomerase in rice."
    Wan J.M., Niu H.B., Zhai H.Q., Zhang X., Jiang L., Qin H.D.
    Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. "The sequence of rice chromosomes 11 and 12, rich in disease resistance genes and recent gene duplications."
    The rice chromosomes 11 and 12 sequencing consortia
    BMC Biol. 3:20-20(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  5. "The rice annotation project database (RAP-DB): 2008 update."
    The rice annotation project (RAP)
    Nucleic Acids Res. 36:D1028-D1033(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENOME REANNOTATION.
    Strain: cv. Nipponbare.
  6. "The genomes of Oryza sativa: a history of duplications."
    Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.
    , Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M., McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.
    PLoS Biol. 3:266-281(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Nipponbare.
  7. "Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice."
    The rice full-length cDNA consortium
    Science 301:376-379(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Nipponbare.
  8. "The rice mutant esp2 greatly accumulates the glutelin precursor and deletes the protein disulfide isomerase."
    Takemoto Y., Coughlan S.J., Okita T.W., Satoh H., Ogawa M., Kumamaru T.
    Plant Physiol. 128:1212-1222(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, DEVELOPMENTAL STAGE, DISRUPTION PHENOTYPE.
  9. "Phylogenetic analyses identify 10 classes of the protein disulfide isomerase family in plants, including single-domain protein disulfide isomerase-related proteins."
    Houston N.L., Fan C., Xiang J.Q., Schulze J.M., Jung R., Boston R.S.
    Plant Physiol. 137:762-778(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.
  10. "The protein disulfide isomerase gene family in bread wheat (T. aestivum L.)."
    d'Aloisio E., Paolacci A.R., Dhanapal A.P., Tanzarella O.A., Porceddu E., Ciaffi M.
    BMC Plant Biol. 10:101-101(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiPDI11_ORYSJ
AccessioniPrimary (citable) accession number: Q53LQ0
Secondary accession number(s): Q52PJ0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 2, 2010
Last sequence update: May 24, 2005
Last modified: September 3, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Oryza sativa (rice)
    Index of Oryza sativa entries and their corresponding gene designations
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi