ID   Q53I03_9GAMM            Unreviewed;       372 AA.
AC   Q53I03;
DT   24-MAY-2005, integrated into UniProtKB/TrEMBL.
DT   24-MAY-2005, sequence version 1.
DT   27-MAR-2024, entry version 84.
DE   RecName: Full=DNA gyrase subunit B {ECO:0000256|ARBA:ARBA00019166};
DE            EC=5.6.2.2 {ECO:0000256|ARBA:ARBA00012895};
DE   Flags: Fragment;
GN   Name=gyrB {ECO:0000313|EMBL:CAI79642.1};
OS   Aeromonas tecta.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Aeromonadales;
OC   Aeromonadaceae; Aeromonas.
OX   NCBI_TaxID=324617 {ECO:0000313|EMBL:CAI79642.1};
RN   [1] {ECO:0000313|EMBL:CAI79642.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Aer106 {ECO:0000313|EMBL:CAI79643.1}, Aer58
RC   {ECO:0000313|EMBL:CAI79644.1}, F581A {ECO:0000313|EMBL:CAI79645.1},
RC   F713G {ECO:0000313|EMBL:CAI79642.1}, and Type strain: F518
RC   {ECO:0000313|EMBL:CAI79641.1};
RA   Demarta A., Kuepfer M., Riegel P., Harf-Monteil C., Tonolla M., Peduzzi R.;
RT   "Aeromonas tecta sp. nov., isolated from clinical and environmental
RT   sources.";
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP-dependent breakage, passage and rejoining of double-
CC         stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC   -!- SIMILARITY: Belongs to the type II topoisomerase GyrB family.
CC       {ECO:0000256|ARBA:ARBA00010708}.
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DR   EMBL; AJ964952; CAI79641.1; -; Genomic_DNA.
DR   EMBL; AJ964953; CAI79642.1; -; Genomic_DNA.
DR   EMBL; AJ964954; CAI79643.1; -; Genomic_DNA.
DR   EMBL; AJ964955; CAI79644.1; -; Genomic_DNA.
DR   EMBL; AJ964956; CAI79645.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q53I03; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   CDD; cd00822; TopoII_Trans_DNA_gyrase; 1.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.40.50.670; -; 1.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   InterPro; IPR001241; Topo_IIA.
DR   InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR   InterPro; IPR000565; Topo_IIA_B.
DR   InterPro; IPR013759; Topo_IIA_B_C.
DR   InterPro; IPR013506; Topo_IIA_bsu_dom2.
DR   InterPro; IPR018522; TopoIIA_CS.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   PANTHER; PTHR45866:SF1; DNA GYRASE SUBUNIT B, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR45866; DNA GYRASE/TOPOISOMERASE SUBUNIT B; 1.
DR   Pfam; PF00204; DNA_gyraseB; 1.
DR   Pfam; PF01751; Toprim; 1.
DR   PRINTS; PR01159; DNAGYRASEB.
DR   SMART; SM00433; TOP2c; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
DR   PROSITE; PS00177; TOPOISOMERASE_II; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT   DOMAIN          303..372
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|PROSITE:PS50880"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:CAI79642.1"
FT   NON_TER         372
FT                   /evidence="ECO:0000313|EMBL:CAI79642.1"
SQ   SEQUENCE   372 AA;  41015 MW;  A83A969A94D2A7D0 CRC64;
     HGVGVSVVNA LSDKLLLTIR RNGHVYEQTY HLGEPQAPLK QIGDSSSGTG TEVRFWPSPT
     IFSDTLYHYE ILAKRLRELS FLNSGVSIRL QDERDGREVH FCYEGGIKAF VEYLNQNKTP
     IHPKVFHFST EQDGIGVEVA MQWNDAYQEG VYCFTNNIPQ RDGGTHLVGF RTALTRTLNT
     YMDKEDYSKK AKSAASGDDV REGLIAVISV KVPDPKFSSQ TKDKLVSSEV KTAVEQAMGE
     KLGEFLLENP GDAKIVVNKI IDAARAREAA RKARELTRRK GALDIAGLPG KLADCQEKDP
     ALSELYIVEG DSAGGSAKQG RNRKNQAILP LKGKILNVEK ARFDKMISSQ EVGTLITALG
     CGIGRDEYNP DK
//