Q53HK3 (Q53HK3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa variant EMBL BAD96297.1
Organism	Homo sapiens (Human) EMBL BAD96297.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	472 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Protein biosynthesis
Ligand	GTP-binding RuleBase RU000323 Nucleotide-binding
Molecular function	Initiation factor EMBL BAD96297.1
Gene Ontology (GO)
Biological_process	GTP catabolic process Inferred from electronic annotation. Source: GOC
Molecular_function	GTP binding Inferred from electronic annotation. Source: UniProtKB-KW GTPase activity Inferred from electronic annotation. Source: InterPro translation initiation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD96297.1

Sequences

	Sequence		Length	Mass (Da)
	Q53HK3 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 7A38CB9ABE8C0983	FASTA	472	51,082
	10 20 30 40 50 60 MAGGEAGVTL GQPHLSRQDL TTLDVTKLTP LSHEVISRQA TINIGTIGHV AHGKSTVVKA 70 80 90 100 110 120 ISGVHTVRFK NELERNITIK LGYANAKIYK LDDPSCPRPE CYRSCGSSTP DEFPTDIPGT 130 140 150 160 170 180 KGNFKLVRHV SFVDCPGHDI LMATMLNGAA VMDAALLLIA GNESCPQPQT SEHLAAIEIM 190 200 210 220 230 240 KLKHILILQN KIDLVKESQA KEQYEQILAF VQGTVAEGAP IIPISAQLKY NIEVVCEYIV 250 260 270 280 290 300 KKIPVPPRDF TSEPRLIVIR SFDVNKPGCE VDDLKGGVAG GSILKGVLKV GQEIEVRPGI 310 320 330 340 350 360 VSKDSEGKLM CKPIFSKIVS LFAEHNDLQY AAPGGLIGVG TKIDPTLCRA DRMVGQVLGA 370 380 390 400 410 420 VGALPEIFTE LEISYFLLRR LLGVRTEGDK KAAKVQKLSK NEVLMVSIGS LSTGGRVSAV 430 440 450 460 470 KADLGKIVLT NPVCTEVGEK IALSRRVEKH WRLIGWGQIR RGVTIKPTVD DD

References

[1]	"Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." Maruyama K., Sugano S. Gene 138:171-174(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Coronary artery EMBL BAD96297.1.
[2]	"Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S. Gene 200:149-156(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Coronary artery EMBL BAD96297.1.
[3]	Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Coronary artery EMBL BAD96297.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK222577 mRNA. Translation: BAD96297.1.
IPI	IPI00297982.
UniGene	Hs.539684.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q53HK3.
Proteomic databases
PRIDE	Q53HK3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG006123.
Gene expression databases
ArrayExpress	Q53HK3.
Family and domain databases
InterPro	IPR000795. EF_GTP-bd_dom. IPR015256. TIF2_gsu_C. IPR009001. Transl_elong_EF1A/Init_IF2_C. IPR004161. Transl_elong_EFTu/EF1A_2. IPR009000. Transl_elong_init/rib_B-barrel. [Graphical view]
Pfam	PF09173. eIF2_C. 1 hit. PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
SUPFAM	SSF50465. Elong_init_C. 1 hit. SSF50447. Translat_factor. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q53HK3_HUMAN

Accession

Primary (citable) accession number: Q53HK3

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.