UniProtKB - Q53GU2 (Q53GU2_HUMAN)
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Protein
UDP-glucuronosyltransferase
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation
GO - Molecular functioni
- glucuronosyltransferase activity Source: UniProtKB-EC
GO - Biological processi
- metabolic process Source: InterPro
Keywordsi
Molecular function | GlycosyltransferaseUniRule annotation, Transferase |
Names & Taxonomyi
Protein namesi | |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 492 – 516 | HelicalUniRule annotationAdd BLAST | 25 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | UniRule annotationAdd BLAST | 22 | |
ChainiPRO_5005143461 | 23 – 528 | UDP-glucuronosyltransferaseUniRule annotationAdd BLAST | 506 |
Proteomic databases
PeptideAtlasi | Q53GU2. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 355 – 398 | UDPGTInterPro annotationAdd BLAST | 44 |
Sequence similaritiesi
Keywords - Domaini
SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotationPhylogenomic databases
eggNOGi | KOG1192. Eukaryota. COG1819. LUCA. |
HOVERGENi | HBG004033. |
Family and domain databases
InterProi | View protein in InterPro IPR002213. UDP_glucos_trans. IPR035595. UDP_glycos_trans_CS. |
Pfami | View protein in Pfam PF00201. UDPGT. 1 hit. |
PROSITEi | View protein in PROSITE PS00375. UDPGT. 1 hit. |
i Sequence
Sequence statusi: Fragment.
Q53GU2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MALKWTTVLL IQLSFYFSSG SCGKVLVWAA EYSLWMNMKT ILKELVQRGH
60 70 80 90 100
EVTVLASSAS ILFDPNDSST LKLEVYPTSL TKTEFENIIM QLVKRLSEIQ
110 120 130 140 150
KDTFWLPFSR EQEILWAIND IIRNFCKDVV SNKKLMKKLQ ESRFDIVFAD
160 170 180 190 200
AYLPCGELLA ELFNIPFVYS HSFSPGYSFE RHSGGFIFPP SYVPVVMSKL
210 220 230 240 250
SDQMTFMERV KNMLYVLYFD FWFQIFNMKK WDQFYSEVLG RPTTLSETMR
260 270 280 290 300
KADIWLMRNS WNFKFPHPFL PNVDFVGGLH CKPAKPLPKE MEEFVQSSGE
310 320 330 340 350
NGVVVFSLGS MVSNMTEERA NVIATALAKI PQKVLWRFDG NKPDALGLNT
360 370 380 390 400
RLYKWIPQND LLGHPKTRAF ITHGGANGIY EAIYHGIPMV GIPLFFDQPD
410 420 430 440 450
NIAHMKAKGA AVRVDFNTMS STDLLNALKT VINDPSYKEN IMKLSRIQHD
460 470 480 490 500
QPVKPLDRAV FWIEFVMRHK GAKHLRVAAH NLTWFQYHSL DVIGFLLACV
510 520
ATVLFIITKC CLFCFWKFAR KGKKGKRD
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK222839 mRNA. Translation: BAD96559.1. |
UniGenei | Hs.201634. |
Similar proteinsi
Entry informationi
Entry namei | Q53GU2_HUMAN | |
Accessioni | Q53GU2Primary (citable) accession number: Q53GU2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 24, 2005 |
Last sequence update: | May 24, 2005 | |
Last modified: | March 28, 2018 | |
This is version 67 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |