Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

UDP-glucuronosyltransferase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferaseUniRule annotation (EC:2.4.1.17UniRule annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Membrane UniRule annotation; Single-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei492 – 516HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37186.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22UniRule annotationAdd BLAST22
ChainiPRO_500514346123 – 528UDP-glucuronosyltransferaseUniRule annotationAdd BLAST506

Proteomic databases

PaxDbiQ53GU2.
PeptideAtlasiQ53GU2.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000265403.

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.UniRule annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
HOVERGENiHBG004033.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q53GU2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKWTTVLL IQLSFYFSSG SCGKVLVWAA EYSLWMNMKT ILKELVQRGH
60 70 80 90 100
EVTVLASSAS ILFDPNDSST LKLEVYPTSL TKTEFENIIM QLVKRLSEIQ
110 120 130 140 150
KDTFWLPFSR EQEILWAIND IIRNFCKDVV SNKKLMKKLQ ESRFDIVFAD
160 170 180 190 200
AYLPCGELLA ELFNIPFVYS HSFSPGYSFE RHSGGFIFPP SYVPVVMSKL
210 220 230 240 250
SDQMTFMERV KNMLYVLYFD FWFQIFNMKK WDQFYSEVLG RPTTLSETMR
260 270 280 290 300
KADIWLMRNS WNFKFPHPFL PNVDFVGGLH CKPAKPLPKE MEEFVQSSGE
310 320 330 340 350
NGVVVFSLGS MVSNMTEERA NVIATALAKI PQKVLWRFDG NKPDALGLNT
360 370 380 390 400
RLYKWIPQND LLGHPKTRAF ITHGGANGIY EAIYHGIPMV GIPLFFDQPD
410 420 430 440 450
NIAHMKAKGA AVRVDFNTMS STDLLNALKT VINDPSYKEN IMKLSRIQHD
460 470 480 490 500
QPVKPLDRAV FWIEFVMRHK GAKHLRVAAH NLTWFQYHSL DVIGFLLACV
510 520
ATVLFIITKC CLFCFWKFAR KGKKGKRD
Length:528
Mass (Da):60,802
Last modified:May 24, 2005 - v1
Checksum:i301ACD2ADF64B1B9
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK222839 mRNA. Translation: BAD96559.1.
UniGeneiHs.201634.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK222839 mRNA. Translation: BAD96559.1.
UniGeneiHs.201634.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000265403.

Proteomic databases

PaxDbiQ53GU2.
PeptideAtlasiQ53GU2.

Protocols and materials databases

DNASUi7365.
Structural Biology KnowledgebaseSearch...

Organism-specific databases

PharmGKBiPA37186.

Phylogenomic databases

eggNOGiKOG1192. Eukaryota.
COG1819. LUCA.
HOVERGENiHBG004033.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53GU2_HUMAN
AccessioniPrimary (citable) accession number: Q53GU2
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 6, 2016
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.