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Q53GD3 (CTL4_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (5) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Choline transporter-like protein 4
Alternative name(s):
Solute carrier family 44 member 4
Gene names
Name:SLC44A4
Synonyms:C6orf29, CTL4, NG22
ORF Names:UNQ441/PRO874
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length710 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein By similarity.

Involvement in disease

An interstitial deletion causing the fusion of exon 10 of CTL4 with the 3'-UTR of NEU has been detected in two patients affected by sialidosis.

Sequence similarities

Belongs to the CTL (choline transporter-like) family.

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q53GD3-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q53GD3-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-422: Missing.
Note: No experimental confirmation available.
Isoform 3 (identifier: Q53GD3-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-76: Missing.
Note: No experimental confirmation available.
Isoform 4 (identifier: Q53GD3-4)

The sequence of this isoform differs from the canonical sequence as follows:
     115-156: Missing.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 710710Choline transporter-like protein 4
PRO_0000191723

Regions

Topological domain1 – 3434Cytoplasmic Potential
Transmembrane35 – 5521Helical; Potential
Topological domain56 – 229174Extracellular Potential
Transmembrane230 – 25021Helical; Potential
Topological domain251 – 2522Cytoplasmic Potential
Transmembrane253 – 27321Helical; Potential
Topological domain274 – 30936Extracellular Potential
Transmembrane310 – 33021Helical; Potential
Topological domain331 – 35828Cytoplasmic Potential
Transmembrane359 – 37921Helical; Potential
Topological domain380 – 45576Extracellular Potential
Transmembrane456 – 47621Helical; Potential
Topological domain477 – 50125Cytoplasmic Potential
Transmembrane502 – 52221Helical; Potential
Topological domain523 – 56038Extracellular Potential
Transmembrane561 – 58121Helical; Potential
Topological domain582 – 59716Cytoplasmic Potential
Transmembrane598 – 61821Helical; Potential
Topological domain619 – 63820Extracellular Potential
Transmembrane639 – 65921Helical; Potential
Topological domain660 – 71051Cytoplasmic Potential

Sites

Site3081Breakpoint for translocation with NEU1

Amino acid modifications

Glycosylation691N-linked (GlcNAc...) Potential
Glycosylation1551N-linked (GlcNAc...) Potential
Glycosylation1971N-linked (GlcNAc...) Potential
Glycosylation2981N-linked (GlcNAc...) Potential
Glycosylation3931N-linked (GlcNAc...) Potential
Glycosylation4051N-linked (GlcNAc...) Potential
Glycosylation4161N-linked (GlcNAc...) Potential

Natural variations

Alternative sequence1 – 422422Missing in isoform 2.
VSP_030998
Alternative sequence1 – 7676Missing in isoform 3.
VSP_046236
Alternative sequence115 – 15642Missing in isoform 4.
VSP_046821
Natural variant61R → L.
Corresponds to variant rs2075798 [ dbSNP | Ensembl ].
VAR_023406
Natural variant1231D → V.
Corresponds to variant rs12661281 [ dbSNP | Ensembl ].
VAR_047020
Natural variant1281G → E. Ref.8
Corresponds to variant rs17856465 [ dbSNP | Ensembl ].
VAR_047021
Natural variant1871V → I. Ref.1 Ref.3 Ref.4 Ref.5 Ref.6 Ref.7 Ref.8 Ref.9
Corresponds to variant rs2242665 [ dbSNP | Ensembl ].
VAR_023407
Natural variant3261M → V. Ref.1 Ref.3 Ref.4 Ref.5 Ref.6 Ref.7 Ref.8
Corresponds to variant rs644827 [ dbSNP | Ensembl ].
VAR_023408
Natural variant3471A → T in a colorectal cancer sample; somatic mutation. Ref.12
VAR_036210
Natural variant4111T → M in a colorectal cancer sample; somatic mutation. Ref.12
VAR_036211
Natural variant4931R → C.
Corresponds to variant rs6915800 [ dbSNP | Ensembl ].
VAR_023409

Experimental info

Sequence conflict117 – 1182Missing in CAH56275. Ref.10
Sequence conflict144 – 1452NR → SS in BAB55083. Ref.1
Sequence conflict379 – 3868LATSGQPQ → PLPTQPATLG in AAD21813. Ref.4
Sequence conflict379 – 3868LATSGQPQ → PLPTQPATLG in BAB63296. Ref.5
Sequence conflict6361Missing in AAH14659. Ref.8

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified November 2, 2010. Version 2.
Checksum: 4DE5B45574C408AD

FASTA71079,254
        10         20         30         40         50         60 
MGGKQRDEDD EAYGKPVKYD PSFRGPIKNR SCTDVICCVL FLLFILGYIV VGIVAWLYGD 

        70         80         90        100        110        120 
PRQVLYPRNS TGAYCGMGEN KDKPYLLYFN IFSCILSSNI ISVAENGLQC PTPQVCVSSC 

       130        140        150        160        170        180 
PEDPWTVGKN EFSQTVGEVF YTKNRNFCLP GVPWNMTVIT SLQQELCPSF LLPSAPALGR 

       190        200        210        220        230        240 
CFPWTNVTPP ALPGITNDTT IQQGISGLID SLNARDISVK IFEDFAQSWY WILVALGVAL 

       250        260        270        280        290        300 
VLSLLFILLL RLVAGPLVLV LILGVLGVLA YGIYYCWEEY RVLRDKGASI SQLGFTTNLS 

       310        320        330        340        350        360 
AYQSVQETWL AALIVLAVLE AILLLMLIFL RQRIRIAIAL LKEASKAVGQ MMSTMFYPLV 

       370        380        390        400        410        420 
TFVLLLICIA YWAMTALYLA TSGQPQYVLW ASNISSPGCE KVPINTSCNP TAHLVNSSCP 

       430        440        450        460        470        480 
GLMCVFQGYS SKGLIQRSVF NLQIYGVLGL FWTLNWVLAL GQCVLAGAFA SFYWAFHKPQ 

       490        500        510        520        530        540 
DIPTFPLISA FIRTLRYHTG SLAFGALILT LVQIARVILE YIDHKLRGVQ NPVARCIMCC 

       550        560        570        580        590        600 
FKCCLWCLEK FIKFLNRNAY IMIAIYGKNF CVSAKNAFML LMRNIVRVVV LDKVTDLLLF 

       610        620        630        640        650        660 
FGKLLVVGGV GVLSFFFFSG RIPGLGKDFK SPHLNYYWLP IMTSILGAYV IASGFFSVFG 

       670        680        690        700        710 
MCVDTLFLCF LEDLERNNGS LDRPYYMSKS LLKILGKKNE APPDNKKRKK 

« Hide

Isoform 2 [UniParc].

Checksum: 6A1ACC9313FB9A3F
Show »

FASTA28832,729
Isoform 3 [UniParc].

Checksum: ABBB965DD14DB114
Show »

FASTA63470,762
Isoform 4 [UniParc].

Checksum: BC10838F8AC3C6DE
Show »

FASTA66874,504

References

« Hide 'large scale' references
[1]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3 AND 4), VARIANTS ILE-187 AND VAL-326.
Tissue: Mammary gland and Prostate.
[2]"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. expand/collapse author list , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M.
Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
[3]Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS ILE-187 AND VAL-326.
Tissue: Small intestine.
[4]"Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse."
Xie T., Rowen L., Aguado B., Ahearn M.E., Madan A., Qin S., Campbell R.D., Hood L.
Genome Res. 13:2621-2636(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS ILE-187 AND VAL-326.
[5]"Homo sapiens 2,229,817bp genomic DNA of 6p21.3 HLA class I region."
Shiina S., Tamiya G., Oka A., Inoko H.
Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS ILE-187 AND VAL-326.
[6]"The DNA sequence and analysis of human chromosome 6."
Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D. expand/collapse author list , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS ILE-187 AND VAL-326.
[7]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANTS ILE-187 AND VAL-326.
[8]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANTS GLU-128; ILE-187 AND VAL-326.
Tissue: Colon.
[9]"Identification of a CTL4/Neu1 fusion transcript in a sialidosis patient."
Uhl J., Penzel R., Sergi C., Kopitz J., Otto H.F., Cantz M.
FEBS Lett. 521:19-23(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-308 (ISOFORM 1), CHROMOSOMAL REARRANGEMENT WITH NEU1, VARIANT ILE-187.
[10]"The full-ORF clone resource of the German cDNA consortium."
Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I.
BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 81-710 (ISOFORMS 1/3).
Tissue: Stomach.
[11]"An electric lobe suppressor for a yeast choline transport mutation belongs to a new family of transporter-like proteins."
O'Regan S., Traiffort E., Ruat M., Cha N., Compaore D., Meunier F.-M.
Proc. Natl. Acad. Sci. U.S.A. 97:1835-1840(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION, NOMENCLATURE.
[12]"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. expand/collapse author list , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E.
Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: VARIANTS [LARGE SCALE ANALYSIS] THR-347 AND MET-411.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK027397 mRNA. Translation: BAB55083.1.
AK300550 mRNA. Translation: BAG62256.1.
AK301596 mRNA. Translation: BAG63084.1.
AY358457 mRNA. Translation: AAQ88822.1.
AK222998 mRNA. Translation: BAD96718.1.
AF134726 Genomic DNA. Translation: AAD21813.1.
BA000025 Genomic DNA. Translation: BAB63296.1.
AL662834 Genomic DNA. Translation: CAI17744.1.
AL671762 Genomic DNA. Translation: CAI18223.2.
AL844853 Genomic DNA. Translation: CAI41851.1.
BX005460 Genomic DNA. Translation: CAM26148.1.
CR936237 Genomic DNA. Translation: CAQ09154.1.
CR759784 Genomic DNA. Translation: CAQ09306.1.
CR388202 Genomic DNA. Translation: CAQ09513.1.
CH471081 Genomic DNA. Translation: EAX03538.1.
BC014659 mRNA. Translation: AAH14659.1.
AF466766 mRNA. Translation: AAL75992.1.
AL833009 mRNA. Translation: CAH56275.1.
RefSeqNP_001171515.1. NM_001178044.1.
NP_001171516.1. NM_001178045.1.
NP_079533.2. NM_025257.2.
UniGeneHs.335355.

3D structure databases

ProteinModelPortalQ53GD3.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9606.ENSP00000229729.

Chemistry

DrugBankDB00122. Choline.

Protein family/group databases

TCDB2.A.92.1.7. the choline transporter-like (ctl) family.

PTM databases

PhosphoSiteQ53GD3.

Polymorphism databases

DMDM311033368.

Proteomic databases

PaxDbQ53GD3.
PRIDEQ53GD3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000229729; ENSP00000229729; ENSG00000204385. [Q53GD3-1]
ENST00000375562; ENSP00000364712; ENSG00000204385. [Q53GD3-4]
ENST00000383379; ENSP00000372870; ENSG00000206378. [Q53GD3-1]
ENST00000415517; ENSP00000414120; ENSG00000229077.
ENST00000417894; ENSP00000389244; ENSG00000235336.
ENST00000425238; ENSP00000399161; ENSG00000228263. [Q53GD3-1]
ENST00000442152; ENSP00000398852; ENSG00000232180.
ENST00000453831; ENSP00000393939; ENSG00000231479. [Q53GD3-1]
ENST00000544672; ENSP00000444109; ENSG00000204385. [Q53GD3-3]
ENST00000546461; ENSP00000449039; ENSG00000231479. [Q53GD3-3]
ENST00000547493; ENSP00000449232; ENSG00000229077.
ENST00000547684; ENSP00000449180; ENSG00000206378. [Q53GD3-3]
ENST00000548188; ENSP00000447560; ENSG00000228263. [Q53GD3-3]
ENST00000549663; ENSP00000449642; ENSG00000228263. [Q53GD3-4]
ENST00000549677; ENSP00000449518; ENSG00000206378. [Q53GD3-4]
ENST00000550401; ENSP00000448474; ENSG00000235336.
ENST00000551168; ENSP00000448088; ENSG00000231479. [Q53GD3-4]
ENST00000553121; ENSP00000447704; ENSG00000232180.
GeneID80736.
KEGGhsa:80736.
UCSCuc010jti.3. human. [Q53GD3-1]

Organism-specific databases

CTD80736.
GeneCardsGC06M031830.
GC06Mi31842.
GC06Mj31818.
GC06Mk31813.
GC06Mm31907.
GC06Mn31822.
GC06Mo31822.
H-InvDBHIX0166072.
HIX0166339.
HIX0167126.
HIX0184154.
HGNCHGNC:13941. SLC44A4.
HPAHPA046977.
HPA054176.
MIM606107. gene.
neXtProtNX_Q53GD3.
PharmGKBPA25930.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG310633.
HOVERGENHBG062155.
InParanoidQ53GD3.
KOK15377.
OMAMFTLLWP.
OrthoDBEOG7FR7G4.
PhylomeDBQ53GD3.
TreeFamTF313325.

Enzyme and pathway databases

ReactomeREACT_111217. Metabolism.
REACT_15518. Transmembrane transport of small molecules.
REACT_20679. Amine compound SLC transporters.

Gene expression databases

ArrayExpressQ53GD3.
BgeeQ53GD3.
GenevestigatorQ53GD3.

Family and domain databases

InterProIPR007603. Choline_transptr-like.
[Graphical view]
PANTHERPTHR12385. PTHR12385. 1 hit.
PfamPF04515. Choline_transpo. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSLC44A4. human.
GeneWikiSLC44A4.
GenomeRNAi80736.
NextBio71058.
PROQ53GD3.
SOURCESearch...

Entry information

Entry nameCTL4_HUMAN
AccessionPrimary (citable) accession number: Q53GD3
Secondary accession number(s): A2BED3 expand/collapse secondary AC list , B0UXX8, B0UZY8, B4DU94, B4DWM2, E9PEK7, Q5JP84, Q5JQ93, Q658S8, Q6UX89, Q8TEW4, Q96C58, Q96K59, Q9Y332
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: November 2, 2010
Last modified: April 16, 2014
This is version 92 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human polymorphisms and disease mutations

Index of human polymorphisms and disease mutations

Human entries with polymorphisms or disease mutations

List of human entries with polymorphisms or disease mutations

Human chromosome 6

Human chromosome 6: entries, gene names and cross-references to MIM