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Protein
Submitted name:

DnaJ (Hsp40) homolog, subfamily A, member 3 variant

Gene

DNAJA3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri223 – 301CR-typePROSITE-ProRule annotationAdd BLAST79

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
DnaJ (Hsp40) homolog, subfamily A, member 3 variantImported
Submitted name:
DnaJ (Hsp40) homolog, subfamily A, member 3, isoform CRA_bImported
Gene namesi
Name:DNAJA3Imported
ORF Names:hCG_15165Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA27410.

Expressioni

Gene expression databases

BgeeiENSG00000103423.
ExpressionAtlasiQ53G26. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
FRMD6Q96NE93EBI-9978078,EBI-741729

Protein-protein interaction databases

IntActiQ53G26. 1 interactor.
STRINGi9606.ENSP00000262375.

Structurei

3D structure databases

SMRiQ53G26.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini93 – 158JInterPro annotationAdd BLAST66
Domaini223 – 301CR-typeInterPro annotationAdd BLAST79

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri223 – 301CR-typePROSITE-ProRule annotationAdd BLAST79

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0715. Eukaryota.
COG0484. LUCA.
HOVERGENiHBG051371.
KOiK09504.
OMAiGPEGFSQ.
OrthoDBiEOG091G09C7.
PhylomeDBiQ53G26.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
2.10.230.10. 1 hit.
HAMAPiMF_01152. DnaJ. 1 hit.
InterProiView protein in InterPro
IPR012724. DnaJ.
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
IPR001305. HSP_DnaJ_Cys-rich_dom.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
PF00684. DnaJ_CXXCXGXG. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 1 hit.
SSF57938. SSF57938. 1 hit.
PROSITEiView protein in PROSITE
PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51188. ZF_CR. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q53G26-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAARCSTRWL LVVVGTPRLP AISGRGARPP REGVVGAWLS RKLSVPAFAS
60 70 80 90 100
SLTSCGPRAL LTLRPGVSLT GTKHNPFICT ASFHTSAPLA KEDYYQILGV
110 120 130 140 150
PRNASQKEIK KAYYQLAKKY HPDTNKDDPK AKEKFSQLAE AYEVLSDEVK
160 170 180 190 200
RKQYDAYGSA GFDPGASGSQ HSYWKGGPTV DPEELFRKIF GEFSSSSFGD
210 220 230 240 250
FQTVFDQPQE YFMELTFNQA AKGVNKEFTV NIMDTCERCN GKGNEPGTKV
260 270 280 290 300
QHCHYCGGSG METINTGPFV MRSTCRRCGG RGSIIISPCV VCRGAGQAKQ
310 320 330 340 350
KKRVMIPVPA GVEDGQTVRM PVGKREIFIT FRVQKSPVFR RDGADIHSDL
360 370 380 390 400
FISIAQALLG GTARAQGLYE TINVTIPPGT QTDQKIRMGG KGIPRINSYG
410 420 430 440 450
YGDHYIHIKI RVPKRLTSRQ QSLILSYAED ETDVEGTVNG VTLTSSGGST
460 470 480
MDSSAGSKAR REAGEDEEGF LSKLKKMFTS
Length:480
Mass (Da):52,489
Last modified:May 24, 2005 - v1
Checksum:i5A57B9020992CF59
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223105 mRNA. Translation: BAD96825.1.
CH471112 Genomic DNA. Translation: EAW85304.1.
CH471112 Genomic DNA. Translation: EAW85305.1.
RefSeqiNP_005138.3. NM_005147.5.
UniGeneiHs.459779.

Genome annotation databases

GeneIDi9093.
KEGGihsa:9093.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223105 mRNA. Translation: BAD96825.1.
CH471112 Genomic DNA. Translation: EAW85304.1.
CH471112 Genomic DNA. Translation: EAW85305.1.
RefSeqiNP_005138.3. NM_005147.5.
UniGeneiHs.459779.

3D structure databases

SMRiQ53G26.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ53G26. 1 interactor.
STRINGi9606.ENSP00000262375.

Protocols and materials databases

DNASUi9093.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9093.
KEGGihsa:9093.

Organism-specific databases

CTDi9093.
PharmGKBiPA27410.

Phylogenomic databases

eggNOGiKOG0715. Eukaryota.
COG0484. LUCA.
HOVERGENiHBG051371.
KOiK09504.
OMAiGPEGFSQ.
OrthoDBiEOG091G09C7.
PhylomeDBiQ53G26.

Miscellaneous databases

ChiTaRSiDNAJA3. human.
GenomeRNAii9093.

Gene expression databases

BgeeiENSG00000103423.
ExpressionAtlasiQ53G26. baseline and differential.

Family and domain databases

CDDicd06257. DnaJ. 1 hit.
Gene3Di1.10.287.110. 1 hit.
2.10.230.10. 1 hit.
HAMAPiMF_01152. DnaJ. 1 hit.
InterProiView protein in InterPro
IPR012724. DnaJ.
IPR002939. DnaJ_C.
IPR001623. DnaJ_domain.
IPR018253. DnaJ_domain_CS.
IPR008971. HSP40/DnaJ_pept-bd.
IPR001305. HSP_DnaJ_Cys-rich_dom.
PfamiView protein in Pfam
PF00226. DnaJ. 1 hit.
PF01556. DnaJ_C. 1 hit.
PF00684. DnaJ_CXXCXGXG. 1 hit.
PRINTSiPR00625. JDOMAIN.
SMARTiView protein in SMART
SM00271. DnaJ. 1 hit.
SUPFAMiSSF46565. SSF46565. 1 hit.
SSF49493. SSF49493. 1 hit.
SSF57938. SSF57938. 1 hit.
PROSITEiView protein in PROSITE
PS00636. DNAJ_1. 1 hit.
PS50076. DNAJ_2. 1 hit.
PS51188. ZF_CR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ53G26_HUMAN
AccessioniPrimary (citable) accession number: Q53G26
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: February 15, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.