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Q53G02 (Q53G02_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 RuleBase RU361136

Short name=Oligosaccharyl transferase subunit DAD1 RuleBase RU361136
EC=2.4.99.18 RuleBase RU361136
OrganismHomo sapiens (Human) EMBL BAD96849.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length113 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains By similarity. RuleBase RU361136

Catalytic activity

Dolichyl diphosphooligosaccharide + [protein]-L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to a protein L-asparagine. RuleBase RU361136

Pathway

Protein modification; protein glycosylation. RuleBase RU361136

Subunit structure

Component of the oligosaccharyltransferase (OST) complex By similarity. RuleBase RU361136

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity RuleBase RU361136.

Sequence similarities

Belongs to the DAD/OST2 family. RuleBase RU361136

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAD96849.1

Sequences

Sequence LengthMass (Da)Tools
Q53G02 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: CA1983CADCEB20F3

FASTA11312,425
        10         20         30         40         50         60 
MSASVVSVIS RFLEEYLSST PQRLKLLDAY LLYILLTGAL QFGYCLLVGT FPFNSFLSGF 

        70         80         90        100        110 
ISCVGSFILA VCLRIQINPQ NKADFQGISP GRAFADFLFA STILHLVVMN FVG 

« Hide

References

[1]"Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides."
Maruyama K., Sugano S.
Gene 138:171-174(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library."
Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S.
Gene 200:149-156(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK223129 mRNA. Translation: BAD96849.1.
RefSeqNP_001335.1. NM_001344.3.
UniGeneHs.82890.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ53G02.

Protocols and materials databases

DNASU1603.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1603.

Organism-specific databases

PharmGKBPA27136.

Phylogenomic databases

HOVERGENHBG004452.

Enzyme and pathway databases

UniPathwayUPA00378.

Family and domain databases

InterProIPR003038. DAD/Ost2.
[Graphical view]
PANTHERPTHR10705. PTHR10705. 1 hit.
PfamPF02109. DAD. 1 hit.
[Graphical view]
PIRSFPIRSF005588. DAD. 1 hit.
ProtoNetSearch...

Other

GenomeRNAi1603.
NextBio6578.

Entry information

Entry nameQ53G02_HUMAN
AccessionPrimary (citable) accession number: Q53G02
Entry history
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: July 9, 2014
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.