ID   CK073_HUMAN             Reviewed;         197 AA.
AC   Q53FT3; Q8WVE8; Q9NVQ2; Q9NZZ1; Q9P022; Q9P0N1;
DT   11-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2006, sequence version 2.
DT   13-JUL-2010, entry version 41.
DE   RecName: Full=Uncharacterized protein C11orf73;
GN   Name=C11orf73; ORFNames=HSPC138, HSPC179, HSPC248;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Umbilical cord blood;
RX   MEDLINE=20499367; PubMed=11042152; DOI=10.1101/gr.140200;
RA   Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G.,
RA   Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W.,
RA   Tao J., Huang Q.-H., Zhou J., Hu G.-X., Gu J., Chen S.-J., Chen Z.;
RT   "Cloning and functional analysis of cDNAs with open reading frames for
RT   300 previously undefined genes expressed in CD34+ hematopoietic
RT   stem/progenitor cells.";
RL   Genome Res. 10:1546-1560(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Teratocarcinoma;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A.,
RA   Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M.,
RA   Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y.,
RA   Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M.,
RA   Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K.,
RA   Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S.,
RA   Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J.,
RA   Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y.,
RA   Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N.,
RA   Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S.,
RA   Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y.,
RA   Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T.,
RA   Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y.,
RA   Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S.,
RA   Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T.,
RA   Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M.,
RA   Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T.,
RA   Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K.,
RA   Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R.,
RA   Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney proximal tubule;
RA   Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y.,
RA   Tanaka A., Yokoyama S.;
RL   Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT ALA-47.
RC   TISSUE=Brain, and Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RA   Colinge J., Superti-Furga G., Bennett K.L.;
RL   Submitted (OCT-2008) to UniProtKB.
CC   -!- FUNCTION: Required for organization and/or function of the
CC       secretory apparatus in Clara cells in lung (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the OPI10 family.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF29102.1; Type=Frameshift; Positions=62, 68;
CC       Sequence=AAF29142.1; Type=Frameshift; Positions=9, 57;
CC       Sequence=AAF36168.1; Type=Frameshift; Positions=67;
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AF151082; AAF36168.1; ALT_FRAME; mRNA.
DR   EMBL; AF161487; AAF29102.1; ALT_FRAME; mRNA.
DR   EMBL; AF161527; AAF29142.1; ALT_FRAME; mRNA.
DR   EMBL; AK001447; BAA91698.1; -; mRNA.
DR   EMBL; AK223198; BAD96918.1; -; mRNA.
DR   EMBL; BC001677; AAH01677.1; -; mRNA.
DR   EMBL; BC006476; AAH06476.1; -; mRNA.
DR   EMBL; BC015991; AAH15991.1; -; mRNA.
DR   EMBL; BC018080; AAH18080.1; -; mRNA.
DR   EMBL; BC021621; AAH21621.1; -; mRNA.
DR   IPI; IPI00410091; -.
DR   RefSeq; NP_057485.2; -.
DR   UniGene; Hs.283322; -.
DR   STRING; Q53FT3; -.
DR   PRIDE; Q53FT3; -.
DR   Ensembl; ENST00000278483; ENSP00000278483; ENSG00000149196; Homo sapiens.
DR   GeneID; 51501; -.
DR   KEGG; hsa:51501; -.
DR   UCSC; uc001pbu.1; human.
DR   CTD; 51501; -.
DR   GeneCards; GC11P085691; -.
DR   HGNC; HGNC:26938; C11orf73.
DR   HPA; HPA035063; -.
DR   eggNOG; prNOG08806; -.
DR   HOGENOM; HBG737086; -.
DR   HOVERGEN; HBG081226; -.
DR   InParanoid; Q53FT3; -.
DR   OMA; VNHVVVF; -.
DR   OrthoDB; EOG9BVVDB; -.
DR   PhylomeDB; Q53FT3; -.
DR   NextBio; 55179; -.
DR   ArrayExpress; Q53FT3; -.
DR   Bgee; Q53FT3; -.
DR   CleanEx; HS_C11orf73; -.
DR   Genevestigator; Q53FT3; -.
DR   GermOnline; ENSG00000149196; Homo sapiens.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008493; DUF775.
DR   PANTHER; PTHR12925; DUF775; 1.
DR   Pfam; PF05603; DUF775; 1.
PE   1: Evidence at protein level;
KW   Complete proteome; Cytoplasm; Developmental protein; Polymorphism.
FT   CHAIN         1    197       Uncharacterized protein C11orf73.
FT                                /FTId=PRO_0000245262.
FT   VARIANT      47     47       P -> A (in dbSNP:rs11539213).
FT                                /FTId=VAR_026968.
FT   CONFLICT     82     82       F -> L (in Ref. 1; AAF29102 and 3;
FT                                BAD96918).
SQ   SEQUENCE   197 AA;  21628 MW;  4FA524439B630511 CRC64;
     MFGCLVAGRL VQTAAQQVAE DKFVFDLPDY ESINHVVVFM LGTIPFPEGM GGSVYFSYPD
     SNGMPVWQLL GFVTNGKPSA IFKISGLKSG EGSQHPFGAM NIVRTPSVAQ IGISVELLDS
     MAQQTPVGNA AVSSVDSFTQ FTQKMLDNFY NFASSFAVSQ AQMTPSPSEM FIPANVVLKW
     YENFQRRLAQ NPLFWKT
//