Q53FK6 (Q53FK6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Thrombospondin 3 variant EMBL BAD96998.1
Organism	Homo sapiens (Human) EMBL BAD96998.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	956 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	EGF-like domain SAAS SAAS018097 RuleBase RU000459
PTM	Disulfide bond SAAS SAAS018097
Gene Ontology (GO)
Biological_process	cell adhesion Inferred from electronic annotation. Source: InterPro
Cellular_component	extracellular region Inferred from electronic annotation. Source: InterPro
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD96998.1

Sequences

	Sequence		Length	Mass (Da)
	Q53FK6 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: E0344BF2E9D2B26B	FASTA	956	104,299
	10 20 30 40 50 60 METQELRGAL ALLLLCFFTS ASQDLQVIDL LTVGESRQMV AVAEKIRTAL LTAGDIYLLS 70 80 90 100 110 120 TFRLPPKQGG VLFGLYSRQD NTRWLEASVV GKINKVLVRY QREDGKVHAV NLQQAGLADG 130 140 150 160 170 180 RTHTVLLRLR GPSRPSPALH LYVNCKLGDQ HAGLPALAPI PPAEVDGLEI RTGQKAYLRM 190 200 210 220 230 240 QGFVESMKII LGGSMARVGA LSECPFQGDE SIHSAVTNAL HSILGEQTKA LVTQLTLFNQ 250 260 270 280 290 300 ILVELRDDIR DQVKEMSLIR NTIMECQVCG FHEQRSHCSP NPCFRGVDCM EVYEYPGYRC 310 320 330 340 350 360 GPCPPGLQGN GTHCSDINEC AHADPCFPGS SCINTMPGFH CEACPRGYKG TQVSGVGIDY 370 380 390 400 410 420 ARASKQVCND IDECNDGNNG GCDPNSICTN TVGSFKCGPC RLGFLGNQSQ GCLPARTCHS 430 440 450 460 470 480 PAHSPCHIHA HCLFERNGAV SCQCNVGWAG NGNVCGTDTD IDGYPDQALP CMDNNKHCKQ 490 500 510 520 530 540 DNCLLTPNSG QEDADNDGVG DQCDDDADGD GIKNVEDNCR LFPNKDQQNS DTDSFGDACD 550 560 570 580 590 600 NCPNVPNNDQ KDTDGNGERD ACDNDVDGDG IPNGLDNCPK VPNPLQTDRD EDGVGDACDS 610 620 630 640 650 660 CPEMSNPTQT DADSDLVGDV CDTNEDSDGD GHQDTKDNCP QLPNSSQLDS DNDGLGDECD 670 680 690 700 710 720 GDDDNDGIPD YVPPGPDNCR LVPNPNQKDS DGNGVGDVCE DDFDNDAVVD PLDVCPESAE 730 740 750 760 770 780 VTLTDFRAYQ TVVLDPEGDA QIDPNWVVLN QGMEIVQTMN SDPGLAVGYT AFNGVDFEGT 790 800 810 820 830 840 FHVNTVTDDD YAGFLFSYQD SGRFYVVMWK QTEQTYWQAT PFRAVAQPGL QLKAVTSVSG 850 860 870 880 890 900 PGEHLRNALW HTGHTPDQVR LLWTDPRNVG WRDKTSYRWQ LLHRPQVGYI RVKLYEGPQL 910 920 930 940 950 VADSGVIIDT SMRGGRLGVF CFSQENIIWS NLQYRCNDTV PEDFEPFRRQ LLQGRV

References

[1]	"Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." Maruyama K., Sugano S. Gene 138:171-174(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Synovial membrane EMBL BAD96998.1.
[2]	"Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S. Gene 200:149-156(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Synovial membrane EMBL BAD96998.1.
[3]	Suzuki Y., Sugano S., Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Synovial membrane EMBL BAD96998.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK223278 mRNA. Translation: BAD96998.1.
IPI	IPI00329535.
UniGene	Hs.169875. Hs.658188.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q53FK6.
Proteomic databases
PRIDE	Q53FK6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG000636.
Gene expression databases
ArrayExpress	Q53FK6.
Family and domain databases
Gene3D	2.60.120.200. 1 hit.
InterPro	IPR008985. ConA-like_lec_gl_sf. IPR013320. ConA-like_subgrp. IPR000742. EG-like_dom. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_CS. IPR018097. EGF_Ca-bd_CS. IPR001791. Laminin_G. IPR024665. Thbs/COMP_coiled-coil. IPR003367. Thrombospondin_3-like_rpt. IPR017897. Thrombospondin_3_rpt. IPR008859. Thrombospondin_C. [Graphical view]
Pfam	PF11598. COMP. 1 hit. PF07645. EGF_CA. 2 hits. PF02412. TSP_3. 6 hits. PF05735. TSP_C. 1 hit. [Graphical view]
SMART	SM00181. EGF. 2 hits. SM00179. EGF_CA. 2 hits. SM00210. TSPN. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 2 hits.
PROSITE	PS01186. EGF_2. 1 hit. PS50026. EGF_3. 3 hits. PS01187. EGF_CA. 2 hits. PS51234. TSP3. 8 hits. PS51236. TSP_CTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q53FK6_HUMAN

Accession

Primary (citable) accession number: Q53FK6

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 68 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.