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Protein
Submitted name:

Programmed cell death 6 variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi36 – 47PROSITE-ProRule annotationAdd BLAST12
Calcium bindingi103 – 114PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Programmed cell death 6 variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA33115.

PTM / Processingi

Proteomic databases

PaxDbiQ53FC3.
PeptideAtlasiQ53FC3.
PRIDEiQ53FC3.

Expressioni

Gene expression databases

GenevisibleiQ53FC3. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000264933.

Structurei

3D structure databases

ProteinModelPortaliQ53FC3.
SMRiQ53FC3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini23 – 58EF-handInterPro annotationAdd BLAST36
Domaini90 – 125EF-handInterPro annotationAdd BLAST36
Domaini156 – 191EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG0037. Eukaryota.
ENOG410YKQK. LUCA.
HOVERGENiHBG004492.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
PfamiView protein in Pfam
PF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
SMARTiView protein in SMART
SM00054. EFh. 5 hits.
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.

Sequencei

Sequence statusi: Fragment.

Q53FC3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYSYRPGP GAGPGPAAGA ALPDQSFLWN VFQRVDKDRS GVISDTELQQ
60 70 80 90 100
ALSNGTWTPF NPVTVRSIIS MFDRENKAGV NFSEFTGVWK YITDWQNVFR
110 120 130 140 150
TYDRDNSGMI DKNELRQALS GFGYRLSDQF HDILIRKFDR QGRGQIAFDD
160 170 180 190
FIQGCIVLQR LTDIFRRYDT DQDGWIQVSY EQYLSMVFSI V
Length:191
Mass (Da):21,896
Last modified:May 24, 2005 - v1
Checksum:iF7459453D1FB898F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223366 mRNA. Translation: BAD97086.1.
RefSeqiNP_001254485.1. NM_001267556.1.
NP_001254486.1. NM_001267557.1.
NP_001254487.1. NM_001267558.1.
NP_001254488.1. NM_001267559.1.
NP_037364.1. NM_013232.3.
UniGeneiHs.50823.

Genome annotation databases

GeneIDi10016.
KEGGihsa:10016.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223366 mRNA. Translation: BAD97086.1.
RefSeqiNP_001254485.1. NM_001267556.1.
NP_001254486.1. NM_001267557.1.
NP_001254487.1. NM_001267558.1.
NP_001254488.1. NM_001267559.1.
NP_037364.1. NM_013232.3.
UniGeneiHs.50823.

3D structure databases

ProteinModelPortaliQ53FC3.
SMRiQ53FC3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000264933.

Proteomic databases

PaxDbiQ53FC3.
PeptideAtlasiQ53FC3.
PRIDEiQ53FC3.

Protocols and materials databases

DNASUi10016.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10016.
KEGGihsa:10016.

Organism-specific databases

CTDi10016.
PharmGKBiPA33115.

Phylogenomic databases

eggNOGiKOG0037. Eukaryota.
ENOG410YKQK. LUCA.
HOVERGENiHBG004492.

Miscellaneous databases

GenomeRNAii10016.

Gene expression databases

GenevisibleiQ53FC3. HS.

Family and domain databases

CDDicd00051. EFh. 1 hit.
Gene3Di1.10.238.10. 1 hit.
InterProiView protein in InterPro
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
PfamiView protein in Pfam
PF13202. EF-hand_5. 1 hit.
PF13499. EF-hand_7. 1 hit.
SMARTiView protein in SMART
SM00054. EFh. 5 hits.
SUPFAMiSSF47473. SSF47473. 1 hit.
PROSITEiView protein in PROSITE
PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ53FC3_HUMAN
AccessioniPrimary (citable) accession number: Q53FC3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: March 15, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.