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Protein
Submitted name:

CD2 antigen (P50), sheep red blood cell receptor

Gene

CD2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
CD2 antigen (P50), sheep red blood cell receptorImported
Submitted name:
CD2 antigen (P50), sheep red blood cell receptor variantImported
Submitted name:
cDNA, FLJ94184, highly similar to Homo sapiens CD2 antigen (p50), sheep red blood cell receptor (CD2), mRNAImported
Gene namesi
Name:CD2Imported
ORF Names:hCG_39065Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000116824.4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei210 – 234HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26198

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_501430951225 – 351Sequence analysisAdd BLAST327

Proteomic databases

MaxQBiQ53F96

Expressioni

Gene expression databases

BgeeiENSG00000116824
ExpressionAtlasiQ53F96 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ53F96
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 126IGvInterPro annotationAdd BLAST95
Domaini135 – 205C2-setInterPro annotationAdd BLAST71

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IW98 Eukaryota
ENOG410Y7BE LUCA
HOVERGENiHBG000262
KOiK06449
OMAiGTQVHQQ
OrthoDBiEOG091G0M7A

Family and domain databases

Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR015632 CD2
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR008424 Ig_C2-set
IPR013106 Ig_V-set
PfamiView protein in Pfam
PF05790 C2-set, 1 hit
PF07686 V-set, 1 hit
PRINTSiPR01870 CD2ANTIGEN
SUPFAMiSSF48726 SSF48726, 2 hits

Sequencei

Sequence statusi: Fragment.

Q53F96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFPCKFVAS FLLIFNVSSK GAVSKEITNA LETWGALGQD INLDIPSFQM
60 70 80 90 100
SDDIDDIKWE KTSDKKKIAQ FRKEKETFKE KDTYKLFKNG TLKIKHLKTD
110 120 130 140 150
DQDIYKVSIY DTKGKNVLEK IFDLKIQERV SKPKISWTCI NTTLTCEVMN
160 170 180 190 200
GTDPELNLYQ DGKHLKLSQR VITHKWTTSL SAKFKCTAGN KVSKESSVEP
210 220 230 240 250
VSCPEKGLDI YLIIGICGGG SLLMVFVALL VFYITKRKKQ RSRRNDEELE
260 270 280 290 300
TRAHRVATEE RGRKPHQIPA STPQNPATSQ HPPPPPGHRS QAPSHRPPPP
310 320 330 340 350
GHRVQHQPQK RPPAPSGTQV HQQKGPPLPR PRVQPKPPHG AAENSLSPSS

N
Length:351
Mass (Da):39,448
Last modified:May 24, 2005 - v1
Checksum:iA03D853C3B618917
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223393 mRNA Translation: BAD97113.1
AK313614 mRNA Translation: BAG36377.1
CH471122 Genomic DNA Translation: EAW56661.1
RefSeqiNP_001315538.1, NM_001328609.1
NP_001758.2, NM_001767.4
UniGeneiHs.523500

Genome annotation databases

GeneIDi914
KEGGihsa:914
UCSCiuc001egu.5 human

Similar proteinsi

Entry informationi

Entry nameiQ53F96_HUMAN
AccessioniPrimary (citable) accession number: Q53F96
Entry historyiIntegrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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