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Protein
Submitted name:

CD2 antigen (P50), sheep red blood cell receptor

Gene

CD2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
CD2 antigen (P50), sheep red blood cell receptorImported
Submitted name:
CD2 antigen (P50), sheep red blood cell receptor variantImported
Submitted name:
cDNA, FLJ94184, highly similar to Homo sapiens CD2 antigen (p50), sheep red blood cell receptor (CD2), mRNAImported
Gene namesi
Name:CD2Imported
ORF Names:hCG_39065Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei210 – 23425HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26198.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 351327Sequence analysisPRO_5007703860Add
BLAST

Proteomic databases

MaxQBiQ53F96.

Expressioni

Gene expression databases

BgeeiENSG00000116824.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000358490.

Structurei

3D structure databases

SMRiQ53F96. Positions 28-206.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini32 – 12695IGvInterPro annotationAdd
BLAST
Domaini135 – 20571C2-setInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IW98. Eukaryota.
ENOG410Y7BE. LUCA.
HOVERGENiHBG000262.
KOiK06449.
OMAiGTQVHQQ.
OrthoDBiEOG091G0M7A.
PhylomeDBiQ53F96.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR015632. CD2.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF05790. C2-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
PRINTSiPR01870. CD2ANTIGEN.
SUPFAMiSSF48726. SSF48726. 2 hits.

Sequencei

Sequence statusi: Fragment.

Q53F96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFPCKFVAS FLLIFNVSSK GAVSKEITNA LETWGALGQD INLDIPSFQM
60 70 80 90 100
SDDIDDIKWE KTSDKKKIAQ FRKEKETFKE KDTYKLFKNG TLKIKHLKTD
110 120 130 140 150
DQDIYKVSIY DTKGKNVLEK IFDLKIQERV SKPKISWTCI NTTLTCEVMN
160 170 180 190 200
GTDPELNLYQ DGKHLKLSQR VITHKWTTSL SAKFKCTAGN KVSKESSVEP
210 220 230 240 250
VSCPEKGLDI YLIIGICGGG SLLMVFVALL VFYITKRKKQ RSRRNDEELE
260 270 280 290 300
TRAHRVATEE RGRKPHQIPA STPQNPATSQ HPPPPPGHRS QAPSHRPPPP
310 320 330 340 350
GHRVQHQPQK RPPAPSGTQV HQQKGPPLPR PRVQPKPPHG AAENSLSPSS

N
Length:351
Mass (Da):39,448
Last modified:May 24, 2005 - v1
Checksum:iA03D853C3B618917
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223393 mRNA. Translation: BAD97113.1.
AK313614 mRNA. Translation: BAG36377.1.
CH471122 Genomic DNA. Translation: EAW56661.1.
RefSeqiNP_001758.2. NM_001767.3.
UniGeneiHs.523500.

Genome annotation databases

GeneIDi914.
KEGGihsa:914.
UCSCiuc001egu.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223393 mRNA. Translation: BAD97113.1.
AK313614 mRNA. Translation: BAG36377.1.
CH471122 Genomic DNA. Translation: EAW56661.1.
RefSeqiNP_001758.2. NM_001767.3.
UniGeneiHs.523500.

3D structure databases

SMRiQ53F96. Positions 28-206.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000358490.

Proteomic databases

MaxQBiQ53F96.

Protocols and materials databases

DNASUi914.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi914.
KEGGihsa:914.
UCSCiuc001egu.5. human.

Organism-specific databases

CTDi914.
PharmGKBiPA26198.

Phylogenomic databases

eggNOGiENOG410IW98. Eukaryota.
ENOG410Y7BE. LUCA.
HOVERGENiHBG000262.
KOiK06449.
OMAiGTQVHQQ.
OrthoDBiEOG091G0M7A.
PhylomeDBiQ53F96.

Miscellaneous databases

GenomeRNAii914.

Gene expression databases

BgeeiENSG00000116824.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR015632. CD2.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR008424. Ig_C2-set.
IPR013106. Ig_V-set.
[Graphical view]
PfamiPF05790. C2-set. 1 hit.
PF07686. V-set. 1 hit.
[Graphical view]
PRINTSiPR01870. CD2ANTIGEN.
SUPFAMiSSF48726. SSF48726. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ53F96_HUMAN
AccessioniPrimary (citable) accession number: Q53F96
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 7, 2016
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.