BRCA1 associated RING domain 1 variant - Homo sapiens (Human)

Contribute

Read comments (1) or add your own

Unreviewed, UniProtKB/TrEMBL Q53F80 (Q53F80_HUMAN)

Last modified May 5, 2009. Version 32. History...

Clusters with 100%, 90%, 50% identity |

Third-party data |

Customize display

text xml rdf/xml gff fasta

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information

Names and origin

Protein names	Submitted name: BRCA1 associated RING domain 1 variant EMBL BAD97129.1
Organism	Homo sapiens (Human) EMBL BAD97129.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	777 AA.
Sequence status	Fragment.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

Ontologies

Keywords
Domain	ANK repeat RuleBase RU003321V2 Repeat RuleBase RU003536V1 Zinc-finger RuleBase RU000353V2
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Experimental info

Non-terminal residue

1

EMBL BAD97129.1

Sequences

Sequence

Length

Mass (Da)

Tools

Q53F80-1 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 8258990E33CB9341
Show »

777

86,496

        10         20         30         40         50         60 
MPDNRQPRNR QPRIRSGNEP RSASAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 

        70         80         90        100        110        120 
VCLGGCEHIF CSNCVSDYIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 

       130        140        150        160        170        180 
SDLKEDKPRK GLFNDAGNKK NSIKMWFSPR SKKVRYVVSK ASVQTQPAIK KDASAQQDSY 

       190        200        210        220        230        240 
EFVSPSPPAD VSERAKKASA RSGKKQKKKT LAEINQKWNL EAEKEDGEFD SKEESKQKLV 

       250        260        270        280        290        300 
SFCSQPSVIS SPQINGEIDL LASGSLTESE CFGSLTEVSL PLAEQIESPD TKSRNEVVTP 

       310        320        330        340        350        360 
EKVCKNYLTS KKSLPLENNG KRGHHNRLSS PISKRCRTSI LSTSGDFVKQ TVPSENIPLP 

       370        380        390        400        410        420 
ECSSPPSCKR KVGGTSGSKN SNMSDEFISL SPGTPPSTLS SSSYRRVMSS PSAMKLLPNM 

       430        440        450        460        470        480 
AVKRNHRGET LLHIASIKGD IPSVEYLLQN GSDPNVKDHA GWTPLHEACN HGHLKVVELL 

       490        500        510        520        530        540 
LQHKALVNTT GYQNDSPLHD AAKNGHVDIV KLLLSYGASR NAVNIFGLRP VDYTDDESMK 

       550        560        570        580        590        600 
SLLLLPEKNE SSSASHCSVM NTGQRRDGPL VLIGSGLSSE QQKMLSGLAV ILKAKKYTEF 

       610        620        630        640        650        660 
DSTVTHVVVP GDAVQSTLKC MLGILNGCWI LKFEWVKACL RRKVCEQEEK YEIPEGPRRS 

       670        680        690        700        710        720 
RLNREQLLPK LFDGCYFYLW GTFKHHPKDN LIKLVTAGGG QILSRKPKPD SDVTQTINTV 

       730        740        750        760        770 
AYHARPDSDQ RFCTQYIIYE DLCNYHPERV RQGKVWKAPS SWFIDCVTSF ELLPLDS

References

[1]	"Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." Maruyama K., Sugano S. Gene 138:171-174(1994) [PubMed: 8125298] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S. Gene 200:149-156(1997) [PubMed: 9373149] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
	AK223409 mRNA. Translation: BAD97129.1.
IPI	IPI00017746.
UniGene	Hs.591642
3D structure databases
SMR	Q53F80. Positions 26-122.
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000138376. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:952. BARD1.
Phylogenomic databases
HOVERGEN	Q53F80.
Gene expression databases
ArrayExpress	Q53F80.
Bgee	Q53F80.
Family and domain databases
InterPro	IPR002110. ANK. IPR001357. BRCT. IPR001841. Znf_RING. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 3 hits. PF00533. BRCT. 2 hits. [Graphical view]
SMART	SM00248. ANK. 3 hits. SM00292. BRCT. 2 hits. SM00184. RING. 1 hit. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 3 hits. PS50172. BRCT. 2 hits. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q53F80_HUMAN

Accession

Primary (citable) accession number: Q53F80

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	May 5, 2009
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information