Q53F80 (Q53F80_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: BRCA1 associated RING domain 1 variant EMBL BAD97129.1
Organism	Homo sapiens (Human) EMBL BAD97129.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	777 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	ANK repeat RuleBase RU003321 Repeat RuleBase RU003536 Zinc-finger RuleBase RU000353
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Molecular_function	zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL BAD97129.1

Sequences

	Sequence		Length	Mass (Da)
	Q53F80 [UniParc]. Last modified May 24, 2005. Version 1. Checksum: 8258990E33CB9341	FASTA	777	86,496
	10 20 30 40 50 60 MPDNRQPRNR QPRIRSGNEP RSASAMEPDG RGAWAHSRAA LDRLEKLLRC SRCTNILREP 70 80 90 100 110 120 VCLGGCEHIF CSNCVSDYIG TGCPVCYTPA WIQDLKINRQ LDSMIQLCSK LRNLLHDNEL 130 140 150 160 170 180 SDLKEDKPRK GLFNDAGNKK NSIKMWFSPR SKKVRYVVSK ASVQTQPAIK KDASAQQDSY 190 200 210 220 230 240 EFVSPSPPAD VSERAKKASA RSGKKQKKKT LAEINQKWNL EAEKEDGEFD SKEESKQKLV 250 260 270 280 290 300 SFCSQPSVIS SPQINGEIDL LASGSLTESE CFGSLTEVSL PLAEQIESPD TKSRNEVVTP 310 320 330 340 350 360 EKVCKNYLTS KKSLPLENNG KRGHHNRLSS PISKRCRTSI LSTSGDFVKQ TVPSENIPLP 370 380 390 400 410 420 ECSSPPSCKR KVGGTSGSKN SNMSDEFISL SPGTPPSTLS SSSYRRVMSS PSAMKLLPNM 430 440 450 460 470 480 AVKRNHRGET LLHIASIKGD IPSVEYLLQN GSDPNVKDHA GWTPLHEACN HGHLKVVELL 490 500 510 520 530 540 LQHKALVNTT GYQNDSPLHD AAKNGHVDIV KLLLSYGASR NAVNIFGLRP VDYTDDESMK 550 560 570 580 590 600 SLLLLPEKNE SSSASHCSVM NTGQRRDGPL VLIGSGLSSE QQKMLSGLAV ILKAKKYTEF 610 620 630 640 650 660 DSTVTHVVVP GDAVQSTLKC MLGILNGCWI LKFEWVKACL RRKVCEQEEK YEIPEGPRRS 670 680 690 700 710 720 RLNREQLLPK LFDGCYFYLW GTFKHHPKDN LIKLVTAGGG QILSRKPKPD SDVTQTINTV 730 740 750 760 770 AYHARPDSDQ RFCTQYIIYE DLCNYHPERV RQGKVWKAPS SWFIDCVTSF ELLPLDS

References

[1]	"Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides." Maruyama K., Sugano S. Gene 138:171-174(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S. Gene 200:149-156(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK223409 mRNA. Translation: BAD97129.1.
IPI	IPI00017746.
UniGene	Hs.591642.
3D structure databases
ProteinModelPortal	Q53F80.
ModBase	Search...
Protein-protein interaction databases
STRING	Q53F80.
Proteomic databases
PRIDE	Q53F80.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG050662.
Gene expression databases
ArrayExpress	Q53F80.
Family and domain databases
Gene3D	1.25.40.20. 1 hit. 3.30.40.10. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR001357. BRCT_dom. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. [Graphical view]
Pfam	PF00023. Ank. 1 hit. PF12796. Ank_2. 1 hit. [Graphical view]
PRINTS	PR01415. ANKYRIN.
SMART	SM00248. ANK. 3 hits. SM00292. BRCT. 2 hits. SM00184. RING. 1 hit. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit. SSF52113. BRCT. 2 hits.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 3 hits. PS50172. BRCT. 2 hits. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q53F80_HUMAN

Accession

Primary (citable) accession number: Q53F80

Entry history

Integrated into UniProtKB/TrEMBL:	May 24, 2005
Last sequence update:	May 24, 2005
Last modified:	April 3, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.