Q53EP0 (FND3B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fibronectin type III domain-containing protein 3B

Alternative name(s):
Factor for adipocyte differentiation 104
HCV NS5A-binding protein 37

Gene names

Name:	FNDC3B
Synonyms:	FAD104, NS5ABP37
ORF Names:	UNQ2421/PRO4979/PRO34274

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1204 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	May be a positive regulator of adipogenesis. Ref.1
Subcellular location	Membrane; Single-pass membrane protein By similarity.
Tissue specificity	Predominantly expressed in white adipose tissue (WAT) especially in the stromal vascular cells. Expressed in adipocyte differentiable 3T3-L1 cells but not in the non-adipogenic cell line NIH-3T3. Expression increased in the early stage of adipogenesis. Ref.1
Sequence similarities	Belongs to the FNDC3 family. Contains 9 fibronectin type-III domains.
Sequence caution	The sequence AAH12204.1 differs from that shown. Reason: Erroneous initiation. The sequence AAH33635.1 differs from that shown. Reason: Erroneous initiation. The sequence AAQ88513.1 differs from that shown. Reason: Erroneous initiation. The sequence AAQ88733.1 differs from that shown. Reason: Erroneous initiation. The sequence BAB15639.1 differs from that shown. Reason: Erroneous initiation. The sequence BAC11480.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Repeat Transmembrane Transmembrane helix
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	positive regulation of fat cell differentiation Inferred from electronic annotation. Source: Compara
Cellular_component	endoplasmic reticulum Inferred from direct assay. Source: HPA integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 3 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q53EP0-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q53EP0-2)

The sequence of this isoform differs from the canonical sequence as follows:
     618-629: ANQWEVAYSGSA → GEVFGNCFIQIQ
     630-1204: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q53EP0-3)

The sequence of this isoform differs from the canonical sequence as follows:
     63-71: GPAEVPMMS → DEVVKRACD
     72-1204: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1204	1204	Fibronectin type III domain-containing protein 3B		PRO_0000284891
Regions
	Transmembrane	1182 – 1202	21	Helical; Potential
	Domain	275 – 374	100	Fibronectin type-III 1
	Domain	379 – 470	92	Fibronectin type-III 2
	Domain	475 – 566	92	Fibronectin type-III 3
	Domain	572 – 666	95	Fibronectin type-III 4
	Domain	671 – 762	92	Fibronectin type-III 5
	Domain	763 – 856	94	Fibronectin type-III 6
	Domain	857 – 954	98	Fibronectin type-III 7
	Domain	956 – 1049	94	Fibronectin type-III 8
	Domain	1054 – 1144	91	Fibronectin type-III 9
	Compositional bias	231 – 243	13	Poly-Gly
Amino acid modifications
	Modified residue	208	1	Phosphoserine Ref.10
	Modified residue	1163	1	Phosphoserine Ref.10
Natural variations
	Alternative sequence	63 – 71	9	GPAEVPMMS → DEVVKRACD in isoform 3.		VSP_024739
	Alternative sequence	72 – 1204	1133	Missing in isoform 3.		VSP_024740
	Alternative sequence	618 – 629	12	ANQWE…YSGSA → GEVFGNCFIQIQ in isoform 2.		VSP_024741
	Alternative sequence	630 – 1204	575	Missing in isoform 2.		VSP_024742
	Natural variant	179	1	T → S. Ref.1 Ref.2 Ref.3 Ref.5 Ref.6 Corresponds to variant rs7652177 [ dbSNP | Ensembl ].		VAR_031856
	Natural variant	927	1	P → S in a breast cancer sample; somatic mutation. Ref.12		VAR_035921
	Natural variant	1080	1	M → V. Corresponds to variant rs2276806 [ dbSNP | Ensembl ].		VAR_047814
Experimental info
	Sequence conflict	37	1	Q → H in AAQ88733. Ref.2
	Sequence conflict	208	1	S → R in BAC53727. Ref.1
	Sequence conflict	212	1	S → A in BAC53727. Ref.1
	Sequence conflict	360	1	N → D in BAG37083. Ref.3
	Sequence conflict	393	1	S → G in BAG37083. Ref.3
	Sequence conflict	448	1	T → A in BAG37083. Ref.3
	Sequence conflict	481	1	P → L in AAQ88513. Ref.2
	Sequence conflict	545	1	K → T in BAC53727. Ref.1
	Sequence conflict	676	1	P → S in BAD97319. Ref.4
	Sequence conflict	854	1	C → W in AAH39297. Ref.6
	Sequence conflict	895	1	N → D in BAC11480. Ref.3
	Sequence conflict	1067	1	G → V in AAQ88513. Ref.2
	Sequence conflict	1083	1	D → G in BAG37083. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified May 1, 2007. Version 2. Checksum: 7E883F4566276CE7	FASTA	1,204	132,888
	10 20 30 40 50 60 MYVTMMMTDQ IPLELPPLLN GEVAMMPHLV NGDAAQQVIL VQVNPGETFT IRAEDGTLQC 70 80 90 100 110 120 IQGPAEVPMM SPNGSIPPIH VPPGYISQVI EDSTGVRRVV VTPQSPECYP PSYPSAMSPT 130 140 150 160 170 180 HHLPPYLTHH PHFIHNSHTA YYPPVTGPGD MPPQFFPQHH LPHTIYGEQE IIPFYGMSTY 190 200 210 220 230 240 ITREDQYSKP PHKKLKDRQI DRQNRLNSPP SSIYKSSCTT VYNGYGKGHS GGSGGGGSGS 250 260 270 280 290 300 GPGIKKTERR ARSSPKSNDS DLQEYELEVK RVQDILSGIE KPQVSNIQAR AVVLSWAPPV 310 320 330 340 350 360 GLSCGPHSGL SFPYSYEVAL SDKGRDGKYK IIYSGEELEC NLKDLRPATD YHVRVYAMYN 370 380 390 400 410 420 SVKGSCSEPV SFTTHSCAPE CPFPPKLAHR SKSSLTLQWK APIDNGSKIT NYLLEWDEGK 430 440 450 460 470 480 RNSGFRQCFF GSQKHCKLTK LCPAMGYTFR LAARNDIGTS GYSQEVVCYT LGNIPQMPSA 490 500 510 520 530 540 PRLVRAGITW VTLQWSKPEG CSPEEVITYT LEIQEDENDN LFHPKYTGED LTCTVKNLKR 550 560 570 580 590 600 STQYKFRLTA SNTEGKSCPS EVLVCTTSPD RPGPPTRPLV KGPVTSHGFS VKWDPPKDNG 610 620 630 640 650 660 GSEILKYLLE ITDGNSEANQ WEVAYSGSAT EYTFTHLKPG TLYKLRACCI STGGHSQCSE 670 680 690 700 710 720 SLPVRTLSIA PGQCRPPRVL GRPKHKEVHL EWDVPASESG CEVSEYSVEM TEPEDVASEV 730 740 750 760 770 780 YHGPELECTV GNLLPGTVYR FRVRALNDGG YGPYSDVSEI TTAAGPPGQC KAPCISCTPD 790 800 810 820 830 840 GCVLVGWESP DSSGADISEY RLEWGEDEES LELIYHGTDT RFEIRDLLPA AQYCCRLQAF 850 860 870 880 890 900 NQAGAGPYSE LVLCQTPASA PDPVSTLCVL EEEPLDAYPD SPSACLVLNW EEPCNNGSEI 910 920 930 940 950 960 LAYTIDLGDT SITVGNTTMH VMKDLLPETT YRIRIQAINE IGAGPFSQFI KAKTRPLPPL 970 980 990 1000 1010 1020 PPRLECAAAG PQSLKLKWGD SNSKTHAAED IVYTLQLEDR NKRFISIYRG PSHTYKVQRL 1030 1040 1050 1060 1070 1080 TEFTCYSFRI QAASEAGEGP FSETYTFSTT KSVPPTIKAP RVTQLEGNSC EILWETVPSM 1090 1100 1110 1120 1130 1140 KGDPVNYILQ VLVGRESEYK QVYKGEEATF QISGLQTNTD YRFRVCACRR CLDTSQELSG 1150 1160 1170 1180 1190 1200 AFSPSAAFVL QRSEVMLTGD MGSLDDPKMK SMMPTDEQFA AIIVLGFATL SILFAFILQY FLMK
	Isoform 2 [UniParc]. Checksum: 86EC7CCBCD47B7B3	FASTA	629	69,572
	10 20 30 40 50 60 MYVTMMMTDQ IPLELPPLLN GEVAMMPHLV NGDAAQQVIL VQVNPGETFT IRAEDGTLQC 70 80 90 100 110 120 IQGPAEVPMM SPNGSIPPIH VPPGYISQVI EDSTGVRRVV VTPQSPECYP PSYPSAMSPT 130 140 150 160 170 180 HHLPPYLTHH PHFIHNSHTA YYPPVTGPGD MPPQFFPQHH LPHTIYGEQE IIPFYGMSTY 190 200 210 220 230 240 ITREDQYSKP PHKKLKDRQI DRQNRLNSPP SSIYKSSCTT VYNGYGKGHS GGSGGGGSGS 250 260 270 280 290 300 GPGIKKTERR ARSSPKSNDS DLQEYELEVK RVQDILSGIE KPQVSNIQAR AVVLSWAPPV 310 320 330 340 350 360 GLSCGPHSGL SFPYSYEVAL SDKGRDGKYK IIYSGEELEC NLKDLRPATD YHVRVYAMYN 370 380 390 400 410 420 SVKGSCSEPV SFTTHSCAPE CPFPPKLAHR SKSSLTLQWK APIDNGSKIT NYLLEWDEGK 430 440 450 460 470 480 RNSGFRQCFF GSQKHCKLTK LCPAMGYTFR LAARNDIGTS GYSQEVVCYT LGNIPQMPSA 490 500 510 520 530 540 PRLVRAGITW VTLQWSKPEG CSPEEVITYT LEIQEDENDN LFHPKYTGED LTCTVKNLKR 550 560 570 580 590 600 STQYKFRLTA SNTEGKSCPS EVLVCTTSPD RPGPPTRPLV KGPVTSHGFS VKWDPPKDNG 610 620 GSEILKYLLE ITDGNSEGEV FGNCFIQIQ
	Isoform 3 [UniParc]. Checksum: 99DC350E3B6A3AC2	FASTA	71	7,844
	10 20 30 40 50 60 MYVTMMMTDQ IPLELPPLLN GEVAMMPHLV NGDAAQQVIL VQVNPGETFT IRAEDGTLQC 70 IQDEVVKRAC D

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation." Tominaga K., Johmura Y., Nishizuka M., Imagawa M. J. Cell Sci. 117:6217-6226(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, FUNCTION, VARIANT SER-179. Tissue: Carcinoma.
[2]	"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment." Clark H.F., Gurney A.L., Abaya E., Baker K., Baldwin D.T., Brush J., Chen J., Chow B., Chui C., Crowley C., Currell B., Deuel B., Dowd P., Eaton D., Foster J.S., Grimaldi C., Gu Q., Hass P.E. , Heldens S., Huang A., Kim H.S., Klimowski L., Jin Y., Johnson S., Lee J., Lewis L., Liao D., Mark M.R., Robbie E., Sanchez C., Schoenfeld J., Seshagiri S., Simmons L., Singh J., Smith V., Stinson J., Vagts A., Vandlen R.L., Watanabe C., Wieand D., Woods K., Xie M.-H., Yansura D.G., Yi S., Yu G., Yuan J., Zhang M., Zhang Z., Goddard A.D., Wood W.I., Godowski P.J., Gray A.M. Genome Res. 13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 320-1204 (ISOFORM 1), VARIANT SER-179.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT SER-179. Tissue: Placenta and Trachea.
[4]	Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S. Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Kidney.
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT SER-179.
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3), VARIANT SER-179. Tissue: Lung, Skin and Testis.
[7]	"Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries." Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y. , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T. DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 403-1204 (ISOFORM 1). Tissue: Placenta.
[8]	Wang L., Li K., Cheng J. Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 710-1204 (ISOFORM 1).
[9]	"The full-ORF clone resource of the German cDNA consortium." Bechtel S., Rosenfelder H., Duda A., Schmidt C.P., Ernst U., Wellenreuther R., Mehrle A., Schuster C., Bahr A., Bloecker H., Heubner D., Hoerlein A., Michel G., Wedler H., Koehrer K., Ottenwaelder B., Poustka A., Wiemann S., Schupp I. BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 728-1204 (ISOFORM 1). Tissue: Melanoma.
[10]	"A quantitative atlas of mitotic phosphorylation." Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., Elledge S.J., Gygi S.P. Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-208 AND SER-1163, MASS SPECTROMETRY. Tissue: Cervix carcinoma.
[11]	"Initial characterization of the human central proteome." Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J. BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract] Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
[12]	"The consensus coding sequences of human breast and colorectal cancers." Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., Dawson D., Willson J.K.V. , Gazdar A.F., Hartigan J., Wu L., Liu C., Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., Vogelstein B., Kinzler K.W., Velculescu V.E. Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract] Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-927.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB098597 mRNA. Translation: BAC53727.1. AY358146 mRNA. Translation: AAQ88513.1. Different initiation. AY358367 mRNA. Translation: AAQ88733.1. Different initiation. AK027052 mRNA. Translation: BAB15639.1. Different initiation. AK075220 mRNA. Translation: BAC11480.1. Different initiation. AK127826 mRNA. Translation: BAG54580.1. AK314478 mRNA. Translation: BAG37083.1. AK223599 mRNA. Translation: BAD97319.1. CH471052 Genomic DNA. Translation: EAW78476.1. CH471052 Genomic DNA. Translation: EAW78472.1. CH471052 Genomic DNA. Translation: EAW78474.1. CH471052 Genomic DNA. Translation: EAW78475.1. BC012204 mRNA. Translation: AAH12204.1. Different initiation. BC033635 mRNA. Translation: AAH33635.1. Different initiation. BC039297 mRNA. Translation: AAH39297.1. AF543840 mRNA. Translation: AAN65261.1. AL157482 mRNA. Translation: CAB75672.1.
IPI	IPI00217490. IPI00386472. IPI00798122.
PIR	T46917.
RefSeq	NP_001128567.1. NM_001135095.1. NP_073600.3. NM_022763.3.
UniGene	Hs.159430.
3D structure databases
HSSP	HSSP built from PDB template 1X3D based on UniProtKB Q9Y2H6.
ProteinModelPortal	Q53EP0.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q53EP0. 7 interactions.
PTM databases
PhosphoSite	Q53EP0.
Polymorphism databases
DMDM	146286181.
Proteomic databases
PaxDb	Q53EP0.
PRIDE	Q53EP0.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000336824; ENSP00000338523; ENSG00000075420. ENST00000415807; ENSP00000411242; ENSG00000075420. ENST00000416957; ENSP00000389094; ENSG00000075420. ENST00000421757; ENSP00000408496; ENSG00000075420. ENST00000423424; ENSP00000392471; ENSG00000075420.
GeneID	64778.
KEGG	hsa:64778.
UCSC	uc003fhy.3. human. uc003fia.3. human.
Organism-specific databases
CTD	64778.
GeneCards	GC03P171757.
H-InvDB	HIX0003861.
HGNC	HGNC:24670. FNDC3B.
HPA	HPA007859.
MIM	611909. gene.
neXtProt	NX_Q53EP0.
PharmGKB	PA134936830.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG12793.
HOVERGEN	HBG100680.
InParanoid	Q53EP0.
OMA	YITREDQ.
OrthoDB	EOG4DFPMN.
Gene expression databases
ArrayExpress	Q53EP0.
Bgee	Q53EP0.
Genevestigator	Q53EP0.
Family and domain databases
Gene3D	2.60.40.10. 9 hits.
InterPro	IPR003961. Fibronectin_type3. IPR013783. Ig-like_fold. [Graphical view]
Pfam	PF00041. fn3. 9 hits. [Graphical view]
SMART	SM00060. FN3. 9 hits. [Graphical view]
SUPFAM	SSF49265. FN_III-like. 9 hits.
PROSITE	PS50853. FN3. 9 hits. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	FNDC3B. human.
GenomeRNAi	64778.
NextBio	66802.
SOURCE	Search...

Entry information

Entry name

FND3B_HUMAN

Accession

Primary (citable) accession number: Q53EP0
Secondary accession number(s): B2RB36 , B3KXR8, D3DNQ7, Q5U5T8, Q6PIJ3, Q6UXG1, Q6UXZ5, Q8IXB2, Q8NBU7, Q96D78, Q9H5I7, Q9NSQ8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 1, 2007
Last sequence update:	May 1, 2007
Last modified:	May 1, 2013
This is version 71 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.