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Q53EP0

- FND3B_HUMAN

UniProt

Q53EP0 - FND3B_HUMAN

Protein

Fibronectin type III domain-containing protein 3B

Gene

FNDC3B

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 2 (01 May 2007)
      Previous versions | rss
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    Functioni

    May be a positive regulator of adipogenesis.1 Publication

    GO - Molecular functioni

    1. poly(A) RNA binding Source: UniProtKB

    GO - Biological processi

    1. positive regulation of fat cell differentiation Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fibronectin type III domain-containing protein 3B
    Alternative name(s):
    Factor for adipocyte differentiation 104
    HCV NS5A-binding protein 37
    Gene namesi
    Name:FNDC3B
    Synonyms:FAD104, NS5ABP37
    ORF Names:UNQ2421/PRO4979/PRO34274
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 3

    Organism-specific databases

    HGNCiHGNC:24670. FNDC3B.

    Subcellular locationi

    Membrane By similarity; Single-pass membrane protein By similarity

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134936830.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 12041204Fibronectin type III domain-containing protein 3BPRO_0000284891Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei208 – 2081Phosphoserine1 Publication
    Modified residuei1163 – 11631Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ53EP0.
    PaxDbiQ53EP0.
    PRIDEiQ53EP0.

    PTM databases

    PhosphoSiteiQ53EP0.

    Expressioni

    Tissue specificityi

    Predominantly expressed in white adipose tissue (WAT) especially in the stromal vascular cells. Expressed in adipocyte differentiable 3T3-L1 cells but not in the non-adipogenic cell line NIH-3T3. Expression increased in the early stage of adipogenesis.1 Publication

    Gene expression databases

    ArrayExpressiQ53EP0.
    BgeeiQ53EP0.
    GenevestigatoriQ53EP0.

    Organism-specific databases

    HPAiHPA007859.

    Interactioni

    Protein-protein interaction databases

    BioGridi122288. 2 interactions.
    IntActiQ53EP0. 8 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ53EP0.
    SMRiQ53EP0. Positions 268-1051.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei1182 – 120221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini278 – 377100Fibronectin type-III 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini381 – 47393Fibronectin type-III 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini477 – 57094Fibronectin type-III 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini574 – 66996Fibronectin type-III 4PROSITE-ProRule annotationAdd
    BLAST
    Domaini673 – 76593Fibronectin type-III 5PROSITE-ProRule annotationAdd
    BLAST
    Domaini766 – 85994Fibronectin type-III 6PROSITE-ProRule annotationAdd
    BLAST
    Domaini871 – 95787Fibronectin type-III 7PROSITE-ProRule annotationAdd
    BLAST
    Domaini958 – 105295Fibronectin type-III 8PROSITE-ProRule annotationAdd
    BLAST
    Domaini1056 – 115398Fibronectin type-III 9PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi231 – 24313Poly-GlyAdd
    BLAST

    Sequence similaritiesi

    Belongs to the FNDC3 family.Curated
    Contains 9 fibronectin type-III domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG12793.
    HOVERGENiHBG100680.
    InParanoidiQ53EP0.
    OMAiMTIRHIL.
    OrthoDBiEOG7F7W8B.
    PhylomeDBiQ53EP0.
    TreeFamiTF316401.

    Family and domain databases

    Gene3Di2.60.40.10. 9 hits.
    InterProiIPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    [Graphical view]
    PfamiPF00041. fn3. 9 hits.
    [Graphical view]
    SMARTiSM00060. FN3. 9 hits.
    [Graphical view]
    SUPFAMiSSF49265. SSF49265. 5 hits.
    PROSITEiPS50853. FN3. 9 hits.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q53EP0-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MYVTMMMTDQ IPLELPPLLN GEVAMMPHLV NGDAAQQVIL VQVNPGETFT     50
    IRAEDGTLQC IQGPAEVPMM SPNGSIPPIH VPPGYISQVI EDSTGVRRVV 100
    VTPQSPECYP PSYPSAMSPT HHLPPYLTHH PHFIHNSHTA YYPPVTGPGD 150
    MPPQFFPQHH LPHTIYGEQE IIPFYGMSTY ITREDQYSKP PHKKLKDRQI 200
    DRQNRLNSPP SSIYKSSCTT VYNGYGKGHS GGSGGGGSGS GPGIKKTERR 250
    ARSSPKSNDS DLQEYELEVK RVQDILSGIE KPQVSNIQAR AVVLSWAPPV 300
    GLSCGPHSGL SFPYSYEVAL SDKGRDGKYK IIYSGEELEC NLKDLRPATD 350
    YHVRVYAMYN SVKGSCSEPV SFTTHSCAPE CPFPPKLAHR SKSSLTLQWK 400
    APIDNGSKIT NYLLEWDEGK RNSGFRQCFF GSQKHCKLTK LCPAMGYTFR 450
    LAARNDIGTS GYSQEVVCYT LGNIPQMPSA PRLVRAGITW VTLQWSKPEG 500
    CSPEEVITYT LEIQEDENDN LFHPKYTGED LTCTVKNLKR STQYKFRLTA 550
    SNTEGKSCPS EVLVCTTSPD RPGPPTRPLV KGPVTSHGFS VKWDPPKDNG 600
    GSEILKYLLE ITDGNSEANQ WEVAYSGSAT EYTFTHLKPG TLYKLRACCI 650
    STGGHSQCSE SLPVRTLSIA PGQCRPPRVL GRPKHKEVHL EWDVPASESG 700
    CEVSEYSVEM TEPEDVASEV YHGPELECTV GNLLPGTVYR FRVRALNDGG 750
    YGPYSDVSEI TTAAGPPGQC KAPCISCTPD GCVLVGWESP DSSGADISEY 800
    RLEWGEDEES LELIYHGTDT RFEIRDLLPA AQYCCRLQAF NQAGAGPYSE 850
    LVLCQTPASA PDPVSTLCVL EEEPLDAYPD SPSACLVLNW EEPCNNGSEI 900
    LAYTIDLGDT SITVGNTTMH VMKDLLPETT YRIRIQAINE IGAGPFSQFI 950
    KAKTRPLPPL PPRLECAAAG PQSLKLKWGD SNSKTHAAED IVYTLQLEDR 1000
    NKRFISIYRG PSHTYKVQRL TEFTCYSFRI QAASEAGEGP FSETYTFSTT 1050
    KSVPPTIKAP RVTQLEGNSC EILWETVPSM KGDPVNYILQ VLVGRESEYK 1100
    QVYKGEEATF QISGLQTNTD YRFRVCACRR CLDTSQELSG AFSPSAAFVL 1150
    QRSEVMLTGD MGSLDDPKMK SMMPTDEQFA AIIVLGFATL SILFAFILQY 1200
    FLMK 1204
    Length:1,204
    Mass (Da):132,888
    Last modified:May 1, 2007 - v2
    Checksum:i7E883F4566276CE7
    GO
    Isoform 2 (identifier: Q53EP0-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         618-629: ANQWEVAYSGSA → GEVFGNCFIQIQ
         630-1204: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:629
    Mass (Da):69,572
    Checksum:i86EC7CCBCD47B7B3
    GO
    Isoform 3 (identifier: Q53EP0-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         63-71: GPAEVPMMS → DEVVKRACD
         72-1204: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:71
    Mass (Da):7,844
    Checksum:i99DC350E3B6A3AC2
    GO

    Sequence cautioni

    The sequence AAH12204.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAH33635.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAQ88513.1 differs from that shown. Reason: Erroneous initiation.
    The sequence AAQ88733.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAB15639.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAC11480.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti37 – 371Q → H in AAQ88733. (PubMed:12975309)Curated
    Sequence conflicti208 – 2081S → R in BAC53727. (PubMed:15564382)Curated
    Sequence conflicti212 – 2121S → A in BAC53727. (PubMed:15564382)Curated
    Sequence conflicti360 – 3601N → D in BAG37083. (PubMed:14702039)Curated
    Sequence conflicti393 – 3931S → G in BAG37083. (PubMed:14702039)Curated
    Sequence conflicti448 – 4481T → A in BAG37083. (PubMed:14702039)Curated
    Sequence conflicti481 – 4811P → L in AAQ88513. (PubMed:12975309)Curated
    Sequence conflicti545 – 5451K → T in BAC53727. (PubMed:15564382)Curated
    Sequence conflicti676 – 6761P → S in BAD97319. 1 PublicationCurated
    Sequence conflicti854 – 8541C → W in AAH39297. (PubMed:15489334)Curated
    Sequence conflicti895 – 8951N → D in BAC11480. (PubMed:14702039)Curated
    Sequence conflicti1067 – 10671G → V in AAQ88513. (PubMed:12975309)Curated
    Sequence conflicti1083 – 10831D → G in BAG37083. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti179 – 1791T → S.5 Publications
    Corresponds to variant rs7652177 [ dbSNP | Ensembl ].
    VAR_031856
    Natural varianti927 – 9271P → S in a breast cancer sample; somatic mutation. 1 Publication
    VAR_035921
    Natural varianti1080 – 10801M → V.
    Corresponds to variant rs2276806 [ dbSNP | Ensembl ].
    VAR_047814

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei63 – 719GPAEVPMMS → DEVVKRACD in isoform 3. 1 PublicationVSP_024739
    Alternative sequencei72 – 12041133Missing in isoform 3. 1 PublicationVSP_024740Add
    BLAST
    Alternative sequencei618 – 62912ANQWE…YSGSA → GEVFGNCFIQIQ in isoform 2. 1 PublicationVSP_024741Add
    BLAST
    Alternative sequencei630 – 1204575Missing in isoform 2. 1 PublicationVSP_024742Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB098597 mRNA. Translation: BAC53727.1.
    AY358146 mRNA. Translation: AAQ88513.1. Different initiation.
    AY358367 mRNA. Translation: AAQ88733.1. Different initiation.
    AK027052 mRNA. Translation: BAB15639.1. Different initiation.
    AK075220 mRNA. Translation: BAC11480.1. Different initiation.
    AK127826 mRNA. Translation: BAG54580.1.
    AK314478 mRNA. Translation: BAG37083.1.
    AK223599 mRNA. Translation: BAD97319.1.
    CH471052 Genomic DNA. Translation: EAW78476.1.
    CH471052 Genomic DNA. Translation: EAW78472.1.
    CH471052 Genomic DNA. Translation: EAW78474.1.
    CH471052 Genomic DNA. Translation: EAW78475.1.
    BC012204 mRNA. Translation: AAH12204.1. Different initiation.
    BC033635 mRNA. Translation: AAH33635.1. Different initiation.
    BC039297 mRNA. Translation: AAH39297.1.
    AF543840 mRNA. Translation: AAN65261.1.
    AL157482 mRNA. Translation: CAB75672.1.
    CCDSiCCDS3217.1. [Q53EP0-1]
    PIRiT46917.
    RefSeqiNP_001128567.1. NM_001135095.1. [Q53EP0-1]
    NP_073600.3. NM_022763.3. [Q53EP0-1]
    UniGeneiHs.744888.

    Genome annotation databases

    EnsembliENST00000336824; ENSP00000338523; ENSG00000075420. [Q53EP0-1]
    ENST00000415807; ENSP00000411242; ENSG00000075420. [Q53EP0-1]
    ENST00000416957; ENSP00000389094; ENSG00000075420. [Q53EP0-1]
    ENST00000421757; ENSP00000408496; ENSG00000075420. [Q53EP0-3]
    ENST00000423424; ENSP00000392471; ENSG00000075420. [Q53EP0-3]
    GeneIDi64778.
    KEGGihsa:64778.
    UCSCiuc003fhy.3. human. [Q53EP0-1]
    uc003fia.3. human. [Q53EP0-2]

    Polymorphism databases

    DMDMi146286181.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB098597 mRNA. Translation: BAC53727.1 .
    AY358146 mRNA. Translation: AAQ88513.1 . Different initiation.
    AY358367 mRNA. Translation: AAQ88733.1 . Different initiation.
    AK027052 mRNA. Translation: BAB15639.1 . Different initiation.
    AK075220 mRNA. Translation: BAC11480.1 . Different initiation.
    AK127826 mRNA. Translation: BAG54580.1 .
    AK314478 mRNA. Translation: BAG37083.1 .
    AK223599 mRNA. Translation: BAD97319.1 .
    CH471052 Genomic DNA. Translation: EAW78476.1 .
    CH471052 Genomic DNA. Translation: EAW78472.1 .
    CH471052 Genomic DNA. Translation: EAW78474.1 .
    CH471052 Genomic DNA. Translation: EAW78475.1 .
    BC012204 mRNA. Translation: AAH12204.1 . Different initiation.
    BC033635 mRNA. Translation: AAH33635.1 . Different initiation.
    BC039297 mRNA. Translation: AAH39297.1 .
    AF543840 mRNA. Translation: AAN65261.1 .
    AL157482 mRNA. Translation: CAB75672.1 .
    CCDSi CCDS3217.1. [Q53EP0-1 ]
    PIRi T46917.
    RefSeqi NP_001128567.1. NM_001135095.1. [Q53EP0-1 ]
    NP_073600.3. NM_022763.3. [Q53EP0-1 ]
    UniGenei Hs.744888.

    3D structure databases

    ProteinModelPortali Q53EP0.
    SMRi Q53EP0. Positions 268-1051.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 122288. 2 interactions.
    IntActi Q53EP0. 8 interactions.

    PTM databases

    PhosphoSitei Q53EP0.

    Polymorphism databases

    DMDMi 146286181.

    Proteomic databases

    MaxQBi Q53EP0.
    PaxDbi Q53EP0.
    PRIDEi Q53EP0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000336824 ; ENSP00000338523 ; ENSG00000075420 . [Q53EP0-1 ]
    ENST00000415807 ; ENSP00000411242 ; ENSG00000075420 . [Q53EP0-1 ]
    ENST00000416957 ; ENSP00000389094 ; ENSG00000075420 . [Q53EP0-1 ]
    ENST00000421757 ; ENSP00000408496 ; ENSG00000075420 . [Q53EP0-3 ]
    ENST00000423424 ; ENSP00000392471 ; ENSG00000075420 . [Q53EP0-3 ]
    GeneIDi 64778.
    KEGGi hsa:64778.
    UCSCi uc003fhy.3. human. [Q53EP0-1 ]
    uc003fia.3. human. [Q53EP0-2 ]

    Organism-specific databases

    CTDi 64778.
    GeneCardsi GC03P171757.
    H-InvDB HIX0003861.
    HGNCi HGNC:24670. FNDC3B.
    HPAi HPA007859.
    MIMi 611909. gene.
    neXtProti NX_Q53EP0.
    PharmGKBi PA134936830.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG12793.
    HOVERGENi HBG100680.
    InParanoidi Q53EP0.
    OMAi MTIRHIL.
    OrthoDBi EOG7F7W8B.
    PhylomeDBi Q53EP0.
    TreeFami TF316401.

    Miscellaneous databases

    ChiTaRSi FNDC3B. human.
    GenomeRNAii 64778.
    NextBioi 66802.
    PROi Q53EP0.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q53EP0.
    Bgeei Q53EP0.
    Genevestigatori Q53EP0.

    Family and domain databases

    Gene3Di 2.60.40.10. 9 hits.
    InterProi IPR003961. Fibronectin_type3.
    IPR013783. Ig-like_fold.
    [Graphical view ]
    Pfami PF00041. fn3. 9 hits.
    [Graphical view ]
    SMARTi SM00060. FN3. 9 hits.
    [Graphical view ]
    SUPFAMi SSF49265. SSF49265. 5 hits.
    PROSITEi PS50853. FN3. 9 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation."
      Tominaga K., Johmura Y., Nishizuka M., Imagawa M.
      J. Cell Sci. 117:6217-6226(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, FUNCTION, VARIANT SER-179.
      Tissue: Carcinoma.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 320-1204 (ISOFORM 1), VARIANT SER-179.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT SER-179.
      Tissue: Placenta and Trachea.
    4. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
      Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Kidney.
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT SER-179.
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3), VARIANT SER-179.
      Tissue: Lung, Skin and Testis.
    7. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
      Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y.
      , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.
      DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 403-1204 (ISOFORM 1).
      Tissue: Placenta.
    8. Wang L., Li K., Cheng J.
      Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 710-1204 (ISOFORM 1).
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 728-1204 (ISOFORM 1).
      Tissue: Melanoma.
    10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-208 AND SER-1163, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-927.

    Entry informationi

    Entry nameiFND3B_HUMAN
    AccessioniPrimary (citable) accession number: Q53EP0
    Secondary accession number(s): B2RB36
    , B3KXR8, D3DNQ7, Q5U5T8, Q6PIJ3, Q6UXG1, Q6UXZ5, Q8IXB2, Q8NBU7, Q96D78, Q9H5I7, Q9NSQ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 1, 2007
    Last sequence update: May 1, 2007
    Last modified: October 1, 2014
    This is version 84 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 3
      Human chromosome 3: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

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