Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Fibronectin type III domain-containing protein 3B

Gene

FNDC3B

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

May be a positive regulator of adipogenesis.1 Publication

GO - Molecular functioni

  • poly(A) RNA binding Source: UniProtKB
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Fibronectin type III domain-containing protein 3B
Alternative name(s):
Factor for adipocyte differentiation 104
HCV NS5A-binding protein 37
Gene namesi
Name:FNDC3B
Synonyms:FAD104, NS5ABP37
ORF Names:UNQ2421/PRO4979/PRO34274
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 3

Organism-specific databases

HGNCiHGNC:24670. FNDC3B.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1182 – 120221HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134936830.

Polymorphism and mutation databases

BioMutaiFNDC3B.
DMDMi146286181.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 12041204Fibronectin type III domain-containing protein 3BPRO_0000284891Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei208 – 2081Phosphoserine1 Publication
Modified residuei1163 – 11631Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ53EP0.
PaxDbiQ53EP0.
PRIDEiQ53EP0.

PTM databases

PhosphoSiteiQ53EP0.

Expressioni

Tissue specificityi

Predominantly expressed in white adipose tissue (WAT) especially in the stromal vascular cells. Expressed in adipocyte differentiable 3T3-L1 cells but not in the non-adipogenic cell line NIH-3T3. Expression increased in the early stage of adipogenesis.1 Publication

Gene expression databases

BgeeiQ53EP0.
ExpressionAtlasiQ53EP0. baseline and differential.
GenevisibleiQ53EP0. HS.

Organism-specific databases

HPAiHPA007859.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CAMK2DQ135573EBI-10242151,EBI-351018
TOX4O948423EBI-10242151,EBI-948613
TRAF2Q129333EBI-10242151,EBI-355744
TRIP13Q156453EBI-10242151,EBI-358993
VAC14Q08AM63EBI-10242151,EBI-2107455

Protein-protein interaction databases

BioGridi122288. 8 interactions.
IntActiQ53EP0. 12 interactions.
STRINGi9606.ENSP00000338523.

Structurei

3D structure databases

ProteinModelPortaliQ53EP0.
SMRiQ53EP0. Positions 372-472.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini278 – 377100Fibronectin type-III 1PROSITE-ProRule annotationAdd
BLAST
Domaini381 – 47393Fibronectin type-III 2PROSITE-ProRule annotationAdd
BLAST
Domaini477 – 57094Fibronectin type-III 3PROSITE-ProRule annotationAdd
BLAST
Domaini574 – 66996Fibronectin type-III 4PROSITE-ProRule annotationAdd
BLAST
Domaini673 – 76593Fibronectin type-III 5PROSITE-ProRule annotationAdd
BLAST
Domaini766 – 85994Fibronectin type-III 6PROSITE-ProRule annotationAdd
BLAST
Domaini871 – 95787Fibronectin type-III 7PROSITE-ProRule annotationAdd
BLAST
Domaini958 – 105295Fibronectin type-III 8PROSITE-ProRule annotationAdd
BLAST
Domaini1056 – 115398Fibronectin type-III 9PROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi231 – 24313Poly-GlyAdd
BLAST

Sequence similaritiesi

Belongs to the FNDC3 family.Curated
Contains 9 fibronectin type-III domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG12793.
GeneTreeiENSGT00800000124108.
HOVERGENiHBG100680.
InParanoidiQ53EP0.
OMAiCTTVYNG.
OrthoDBiEOG7F7W8B.
PhylomeDBiQ53EP0.
TreeFamiTF316401.

Family and domain databases

Gene3Di2.60.40.10. 9 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00041. fn3. 9 hits.
[Graphical view]
SMARTiSM00060. FN3. 9 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 5 hits.
PROSITEiPS50853. FN3. 9 hits.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q53EP0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MYVTMMMTDQ IPLELPPLLN GEVAMMPHLV NGDAAQQVIL VQVNPGETFT
60 70 80 90 100
IRAEDGTLQC IQGPAEVPMM SPNGSIPPIH VPPGYISQVI EDSTGVRRVV
110 120 130 140 150
VTPQSPECYP PSYPSAMSPT HHLPPYLTHH PHFIHNSHTA YYPPVTGPGD
160 170 180 190 200
MPPQFFPQHH LPHTIYGEQE IIPFYGMSTY ITREDQYSKP PHKKLKDRQI
210 220 230 240 250
DRQNRLNSPP SSIYKSSCTT VYNGYGKGHS GGSGGGGSGS GPGIKKTERR
260 270 280 290 300
ARSSPKSNDS DLQEYELEVK RVQDILSGIE KPQVSNIQAR AVVLSWAPPV
310 320 330 340 350
GLSCGPHSGL SFPYSYEVAL SDKGRDGKYK IIYSGEELEC NLKDLRPATD
360 370 380 390 400
YHVRVYAMYN SVKGSCSEPV SFTTHSCAPE CPFPPKLAHR SKSSLTLQWK
410 420 430 440 450
APIDNGSKIT NYLLEWDEGK RNSGFRQCFF GSQKHCKLTK LCPAMGYTFR
460 470 480 490 500
LAARNDIGTS GYSQEVVCYT LGNIPQMPSA PRLVRAGITW VTLQWSKPEG
510 520 530 540 550
CSPEEVITYT LEIQEDENDN LFHPKYTGED LTCTVKNLKR STQYKFRLTA
560 570 580 590 600
SNTEGKSCPS EVLVCTTSPD RPGPPTRPLV KGPVTSHGFS VKWDPPKDNG
610 620 630 640 650
GSEILKYLLE ITDGNSEANQ WEVAYSGSAT EYTFTHLKPG TLYKLRACCI
660 670 680 690 700
STGGHSQCSE SLPVRTLSIA PGQCRPPRVL GRPKHKEVHL EWDVPASESG
710 720 730 740 750
CEVSEYSVEM TEPEDVASEV YHGPELECTV GNLLPGTVYR FRVRALNDGG
760 770 780 790 800
YGPYSDVSEI TTAAGPPGQC KAPCISCTPD GCVLVGWESP DSSGADISEY
810 820 830 840 850
RLEWGEDEES LELIYHGTDT RFEIRDLLPA AQYCCRLQAF NQAGAGPYSE
860 870 880 890 900
LVLCQTPASA PDPVSTLCVL EEEPLDAYPD SPSACLVLNW EEPCNNGSEI
910 920 930 940 950
LAYTIDLGDT SITVGNTTMH VMKDLLPETT YRIRIQAINE IGAGPFSQFI
960 970 980 990 1000
KAKTRPLPPL PPRLECAAAG PQSLKLKWGD SNSKTHAAED IVYTLQLEDR
1010 1020 1030 1040 1050
NKRFISIYRG PSHTYKVQRL TEFTCYSFRI QAASEAGEGP FSETYTFSTT
1060 1070 1080 1090 1100
KSVPPTIKAP RVTQLEGNSC EILWETVPSM KGDPVNYILQ VLVGRESEYK
1110 1120 1130 1140 1150
QVYKGEEATF QISGLQTNTD YRFRVCACRR CLDTSQELSG AFSPSAAFVL
1160 1170 1180 1190 1200
QRSEVMLTGD MGSLDDPKMK SMMPTDEQFA AIIVLGFATL SILFAFILQY

FLMK
Length:1,204
Mass (Da):132,888
Last modified:May 1, 2007 - v2
Checksum:i7E883F4566276CE7
GO
Isoform 2 (identifier: Q53EP0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     618-629: ANQWEVAYSGSA → GEVFGNCFIQIQ
     630-1204: Missing.

Note: No experimental confirmation available.
Show »
Length:629
Mass (Da):69,572
Checksum:i86EC7CCBCD47B7B3
GO
Isoform 3 (identifier: Q53EP0-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     63-71: GPAEVPMMS → DEVVKRACD
     72-1204: Missing.

Note: No experimental confirmation available.
Show »
Length:71
Mass (Da):7,844
Checksum:i99DC350E3B6A3AC2
GO

Sequence cautioni

The sequence AAH12204.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAH33635.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAQ88513.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAQ88733.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence BAB15639.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence BAC11480.1 differs from that shown. Reason: Erroneous initiation. Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti37 – 371Q → H in AAQ88733 (PubMed:12975309).Curated
Sequence conflicti208 – 2081S → R in BAC53727 (PubMed:15564382).Curated
Sequence conflicti212 – 2121S → A in BAC53727 (PubMed:15564382).Curated
Sequence conflicti360 – 3601N → D in BAG37083 (PubMed:14702039).Curated
Sequence conflicti393 – 3931S → G in BAG37083 (PubMed:14702039).Curated
Sequence conflicti448 – 4481T → A in BAG37083 (PubMed:14702039).Curated
Sequence conflicti481 – 4811P → L in AAQ88513 (PubMed:12975309).Curated
Sequence conflicti545 – 5451K → T in BAC53727 (PubMed:15564382).Curated
Sequence conflicti676 – 6761P → S in BAD97319 (Ref. 4) Curated
Sequence conflicti854 – 8541C → W in AAH39297 (PubMed:15489334).Curated
Sequence conflicti895 – 8951N → D in BAC11480 (PubMed:14702039).Curated
Sequence conflicti1067 – 10671G → V in AAQ88513 (PubMed:12975309).Curated
Sequence conflicti1083 – 10831D → G in BAG37083 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti179 – 1791T → S.5 Publications
Corresponds to variant rs7652177 [ dbSNP | Ensembl ].
VAR_031856
Natural varianti927 – 9271P → S in a breast cancer sample; somatic mutation. 1 Publication
VAR_035921
Natural varianti1080 – 10801M → V.
Corresponds to variant rs2276806 [ dbSNP | Ensembl ].
VAR_047814

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei63 – 719GPAEVPMMS → DEVVKRACD in isoform 3. 1 PublicationVSP_024739
Alternative sequencei72 – 12041133Missing in isoform 3. 1 PublicationVSP_024740Add
BLAST
Alternative sequencei618 – 62912ANQWE…YSGSA → GEVFGNCFIQIQ in isoform 2. 1 PublicationVSP_024741Add
BLAST
Alternative sequencei630 – 1204575Missing in isoform 2. 1 PublicationVSP_024742Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB098597 mRNA. Translation: BAC53727.1.
AY358146 mRNA. Translation: AAQ88513.1. Different initiation.
AY358367 mRNA. Translation: AAQ88733.1. Different initiation.
AK027052 mRNA. Translation: BAB15639.1. Different initiation.
AK075220 mRNA. Translation: BAC11480.1. Different initiation.
AK127826 mRNA. Translation: BAG54580.1.
AK314478 mRNA. Translation: BAG37083.1.
AK223599 mRNA. Translation: BAD97319.1.
CH471052 Genomic DNA. Translation: EAW78476.1.
CH471052 Genomic DNA. Translation: EAW78472.1.
CH471052 Genomic DNA. Translation: EAW78474.1.
CH471052 Genomic DNA. Translation: EAW78475.1.
BC012204 mRNA. Translation: AAH12204.1. Different initiation.
BC033635 mRNA. Translation: AAH33635.1. Different initiation.
BC039297 mRNA. Translation: AAH39297.1.
AF543840 mRNA. Translation: AAN65261.1.
AL157482 mRNA. Translation: CAB75672.1.
CCDSiCCDS3217.1. [Q53EP0-1]
PIRiT46917.
RefSeqiNP_001128567.1. NM_001135095.1. [Q53EP0-1]
NP_073600.3. NM_022763.3. [Q53EP0-1]
UniGeneiHs.744888.

Genome annotation databases

EnsembliENST00000336824; ENSP00000338523; ENSG00000075420.
ENST00000415807; ENSP00000411242; ENSG00000075420.
ENST00000416957; ENSP00000389094; ENSG00000075420.
ENST00000421757; ENSP00000408496; ENSG00000075420. [Q53EP0-3]
ENST00000423424; ENSP00000392471; ENSG00000075420. [Q53EP0-3]
GeneIDi64778.
KEGGihsa:64778.
UCSCiuc003fhy.3. human. [Q53EP0-1]
uc003fia.3. human. [Q53EP0-2]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB098597 mRNA. Translation: BAC53727.1.
AY358146 mRNA. Translation: AAQ88513.1. Different initiation.
AY358367 mRNA. Translation: AAQ88733.1. Different initiation.
AK027052 mRNA. Translation: BAB15639.1. Different initiation.
AK075220 mRNA. Translation: BAC11480.1. Different initiation.
AK127826 mRNA. Translation: BAG54580.1.
AK314478 mRNA. Translation: BAG37083.1.
AK223599 mRNA. Translation: BAD97319.1.
CH471052 Genomic DNA. Translation: EAW78476.1.
CH471052 Genomic DNA. Translation: EAW78472.1.
CH471052 Genomic DNA. Translation: EAW78474.1.
CH471052 Genomic DNA. Translation: EAW78475.1.
BC012204 mRNA. Translation: AAH12204.1. Different initiation.
BC033635 mRNA. Translation: AAH33635.1. Different initiation.
BC039297 mRNA. Translation: AAH39297.1.
AF543840 mRNA. Translation: AAN65261.1.
AL157482 mRNA. Translation: CAB75672.1.
CCDSiCCDS3217.1. [Q53EP0-1]
PIRiT46917.
RefSeqiNP_001128567.1. NM_001135095.1. [Q53EP0-1]
NP_073600.3. NM_022763.3. [Q53EP0-1]
UniGeneiHs.744888.

3D structure databases

ProteinModelPortaliQ53EP0.
SMRiQ53EP0. Positions 372-472.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122288. 8 interactions.
IntActiQ53EP0. 12 interactions.
STRINGi9606.ENSP00000338523.

PTM databases

PhosphoSiteiQ53EP0.

Polymorphism and mutation databases

BioMutaiFNDC3B.
DMDMi146286181.

Proteomic databases

MaxQBiQ53EP0.
PaxDbiQ53EP0.
PRIDEiQ53EP0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000336824; ENSP00000338523; ENSG00000075420.
ENST00000415807; ENSP00000411242; ENSG00000075420.
ENST00000416957; ENSP00000389094; ENSG00000075420.
ENST00000421757; ENSP00000408496; ENSG00000075420. [Q53EP0-3]
ENST00000423424; ENSP00000392471; ENSG00000075420. [Q53EP0-3]
GeneIDi64778.
KEGGihsa:64778.
UCSCiuc003fhy.3. human. [Q53EP0-1]
uc003fia.3. human. [Q53EP0-2]

Organism-specific databases

CTDi64778.
GeneCardsiGC03P171757.
H-InvDBHIX0003861.
HGNCiHGNC:24670. FNDC3B.
HPAiHPA007859.
MIMi611909. gene.
neXtProtiNX_Q53EP0.
PharmGKBiPA134936830.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG12793.
GeneTreeiENSGT00800000124108.
HOVERGENiHBG100680.
InParanoidiQ53EP0.
OMAiCTTVYNG.
OrthoDBiEOG7F7W8B.
PhylomeDBiQ53EP0.
TreeFamiTF316401.

Miscellaneous databases

ChiTaRSiFNDC3B. human.
GenomeRNAii64778.
NextBioi66802.
PROiQ53EP0.
SOURCEiSearch...

Gene expression databases

BgeeiQ53EP0.
ExpressionAtlasiQ53EP0. baseline and differential.
GenevisibleiQ53EP0. HS.

Family and domain databases

Gene3Di2.60.40.10. 9 hits.
InterProiIPR003961. FN3_dom.
IPR013783. Ig-like_fold.
[Graphical view]
PfamiPF00041. fn3. 9 hits.
[Graphical view]
SMARTiSM00060. FN3. 9 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 5 hits.
PROSITEiPS50853. FN3. 9 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Fad24, a mammalian homolog of Noc3p, is a positive regulator in adipocyte differentiation."
    Tominaga K., Johmura Y., Nishizuka M., Imagawa M.
    J. Cell Sci. 117:6217-6226(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, FUNCTION, VARIANT SER-179.
    Tissue: Carcinoma.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 320-1204 (ISOFORM 1), VARIANT SER-179.
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT SER-179.
    Tissue: Placenta and Trachea.
  4. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Kidney.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT SER-179.
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3), VARIANT SER-179.
    Tissue: Lung, Skin and Testis.
  7. "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries."
    Otsuki T., Ota T., Nishikawa T., Hayashi K., Suzuki Y., Yamamoto J., Wakamatsu A., Kimura K., Sakamoto K., Hatano N., Kawai Y., Ishii S., Saito K., Kojima S., Sugiyama T., Ono T., Okano K., Yoshikawa Y.
    , Aotsuka S., Sasaki N., Hattori A., Okumura K., Nagai K., Sugano S., Isogai T.
    DNA Res. 12:117-126(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 403-1204 (ISOFORM 1).
    Tissue: Placenta.
  8. Wang L., Li K., Cheng J.
    Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 710-1204 (ISOFORM 1).
  9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 728-1204 (ISOFORM 1).
    Tissue: Melanoma.
  10. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-208 AND SER-1163, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  12. Cited for: VARIANT [LARGE SCALE ANALYSIS] SER-927.

Entry informationi

Entry nameiFND3B_HUMAN
AccessioniPrimary (citable) accession number: Q53EP0
Secondary accession number(s): B2RB36
, B3KXR8, D3DNQ7, Q5U5T8, Q6PIJ3, Q6UXG1, Q6UXZ5, Q8IXB2, Q8NBU7, Q96D78, Q9H5I7, Q9NSQ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2007
Last modified: July 22, 2015
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 3
    Human chromosome 3: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.