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Protein
Submitted name:

Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 8 isoform a variant

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 7 (Cationic amino acid transporter, y+ system), member 8 isoform a variantImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 6021HelicalSequence analysisAdd
BLAST
Transmembranei72 – 9322HelicalSequence analysisAdd
BLAST
Transmembranei113 – 13119HelicalSequence analysisAdd
BLAST
Transmembranei163 – 18321HelicalSequence analysisAdd
BLAST
Transmembranei189 – 21022HelicalSequence analysisAdd
BLAST
Transmembranei231 – 24818HelicalSequence analysisAdd
BLAST
Transmembranei268 – 29023HelicalSequence analysisAdd
BLAST
Transmembranei323 – 34220HelicalSequence analysisAdd
BLAST
Transmembranei363 – 38119HelicalSequence analysisAdd
BLAST
Transmembranei387 – 41125HelicalSequence analysisAdd
BLAST
Transmembranei423 – 44422HelicalSequence analysisAdd
BLAST
Transmembranei450 – 46920HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ53EM9.
PRIDEiQ53EM9.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000320378.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG1287. Eukaryota.
COG0531. LUCA.
HOVERGENiHBG000476.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
IPR004760. L_AA_transporter.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
TIGRFAMsiTIGR00911. 2A0308. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q53EM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEGARHRNN TEKKHPGGGE SDASPEAGSG GGGVALKKEI GLVSACGIIV
60 70 80 90 100
GNIIGSGIFV SPKGVLENAG SVGLALIVWI VTGFITVVGA LCYAELGVTI
110 120 130 140 150
PKSGGDYSYV KDIFGGLAGF LRLWIAVLVI YPTNQAVIAL TFSNYVLQPL
160 170 180 190 200
FPTCFPPESG LRLLAAICLL LLTWVNCSSV RWATRVQDIF TAGKLLALAL
210 220 230 240 250
IIIMGIVQIC KGEYFWLEPK NAFENFQEPD IGLVALAFLQ GSFAYGGWNF
260 270 280 290 300
LNYVTEELVD PYKNLPRAIF ISIPLVTFVY VVANVAYVTA MSPQELLASN
310 320 330 340 350
AVAVTFGEKL LGVMAWIMPI SVALSTFGGV NGSLFTSSRL FFAGAREGHL
360 370 380 390 400
PSVLAMIHVK RCTPIPALLF TCISTLLMLV TSDMYTLINY VGFINYLFYG
410 420 430 440 450
VTVVGQIVLR WKKPDIPRPI KINLLFPIIY LLFWAFLLVF SLWSEPVVCG
460 470 480 490 500
IGLAIMLTGV PVYFLGVYWQ HKPKCFSDFI ELLTLVSQKM CVVVYPEVER
510 520 530
GSGTEEANED MEEQQQPMYQ PTPTKDKDVA GQPQP
Length:535
Mass (Da):58,362
Last modified:May 24, 2005 - v1
Checksum:iAC0F4A4BAE245E47
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223610 mRNA. Translation: BAD97330.1.
RefSeqiNP_036376.2. NM_012244.3.
UniGeneiHs.596643.

Genome annotation databases

GeneIDi23428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223610 mRNA. Translation: BAD97330.1.
RefSeqiNP_036376.2. NM_012244.3.
UniGeneiHs.596643.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000320378.

Proteomic databases

PaxDbiQ53EM9.
PRIDEiQ53EM9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi23428.

Organism-specific databases

CTDi23428.

Phylogenomic databases

eggNOGiKOG1287. Eukaryota.
COG0531. LUCA.
HOVERGENiHBG000476.

Miscellaneous databases

GenomeRNAii23428.

Family and domain databases

InterProiIPR002293. AA/rel_permease1.
IPR004760. L_AA_transporter.
[Graphical view]
PANTHERiPTHR11785. PTHR11785. 1 hit.
PfamiPF13520. AA_permease_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006060. AA_transporter. 1 hit.
TIGRFAMsiTIGR00911. 2A0308. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides."
    Maruyama K., Sugano S.
    Gene 138:171-174(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  2. "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library."
    Suzuki Y., Yoshitomo K., Maruyama K., Suyama A., Sugano S.
    Gene 200:149-156(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  3. Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S.
    Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiQ53EM9_HUMAN
AccessioniPrimary (citable) accession number: Q53EM9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 24, 2005
Last sequence update: May 24, 2005
Last modified: June 8, 2016
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.