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Reviewed, UniProtKB/Swiss-Prot Q539E5 (APX1_CHLVR)

Last modified May 5, 2009. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Putative ascorbate peroxidase
    EC=1.11.1.11
Alternative name(s):
    HvAPX1
Gene names
Name: APX1
OrganismChlorohydra viridissima (Hydra) (Hydra viridis)
Taxonomic identifier6082 [NCBI]
Taxonomic lineageEukaryotaMetazoaCnidariaHydrozoaHydroidaAnthomedusaeHydridaeHydra

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

May play a role in the protection of oocyte incorporated cells from rapid apoptotic degradation.

Catalytic activity

L-ascorbate + H2O2 = dehydroascorbate + 2 H2O.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Developmental stage

Expressed exclusively during oogenesis. Ref.1

Miscellaneous

The gene for this protein may have been transferred horizontally following an endosymbiotic event early in evolution of the Hydra lineage as an RNA or cDNA intermediate.

Sequence similarities

Belongs to the peroxidase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1616 Potential
Chain17 – 367351Putative ascorbate peroxidase
PRO_0000023637

Sites

Active site581Proton acceptor By similarity
Site541Transition state stabilizer By similarity

Amino acid modifications

Glycosylation1191N-linked (GlcNAc...) Potential
Glycosylation2391N-linked (GlcNAc...) Potential
Glycosylation3561N-linked (GlcNAc...) Potential
Disulfide bond60 ↔ 66 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q539E5-1 [UniParc].

Last modified May 24, 2005. Version 1.
Checksum: 91E0A494F416A10D

FASTA36740,790
        10         20         30         40         50         60 
MVPVIWLTVL IVLVDSLQII PTFHDFQRAK TDLLGLIESV KRGDDLPMIA GTVRLAFHDC 

        70         80         90        100        110        120 
IGKGKCDGCI DHSKPGNAGL KRVTDRLDAL YDASYKGKIS RADFYALASV TALTRSTANL 

       130        140        150        160        170        180 
SDKYNGLRKF KVGRKDCSTS PVESIDSSDI PRGSDGTSKT LQFFKSEFGM KTQEAVALLG 

       190        200        210        220        230        240 
AHTLGRCSLQ NSGFVGSWVD QRFSTAPPGE ENLSPTSILD NAYYRMIIDI VPWTQVNING 

       250        260        270        280        290        300 
TRIQWQEPSN SIPNDKLPES KRSPLLLNSD MAISWIIKPS DALGTVSCRP TSLKTPCRHS 

       310        320        330        340        350        360 
NAHTFAKIYA KNNALWVKDF TKAFNKMIEM NENKLRKAPI FNGYFDEMNS HDEPINESVD 


EISEDIF 

« Hide

References

[1]"Symbiotic Hydra express a plant-like peroxidase gene during oogenesis."
Habetha M., Bosch T.C.G.
J. Exp. Biol. 208:2157-2165(2005) [PubMed: 15914659] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE.
Strain: A99.

Cross-references

Sequence databases

AY608909 mRNA. Translation: AAU07981.1.

3D structure databases

ModBaseSearch...

Protein family/group databases

PeroxiBase2285. HviNAnPrx01.

Family and domain databases

InterProIPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00458. PEROXIDASE.
PROSITEPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. False negative.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAPX1_CHLVR
AccessionPrimary (citable) accession number: Q539E5
Entry history
Integrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: May 24, 2005
Last modified: May 5, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents