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Protein

Putative membrane protein ActII-3

Gene

actII-3

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Protein family/group databases

TCDBi2.A.6.5.1. the resistance-nodulation-cell division (rnd) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative membrane protein ActII-3
Gene namesi
Name:actII-3
Ordered Locus Names:SCO5084
ORF Names:SCBAC28G1.10
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
Proteomesi
  • UP000001973 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei14 – 3421HelicalSequence analysisAdd
BLAST
Transmembranei175 – 19521HelicalSequence analysisAdd
BLAST
Transmembranei199 – 21921HelicalSequence analysisAdd
BLAST
Transmembranei235 – 25521HelicalSequence analysisAdd
BLAST
Transmembranei281 – 30121HelicalSequence analysisAdd
BLAST
Transmembranei313 – 33321HelicalSequence analysisAdd
BLAST
Transmembranei369 – 38921HelicalSequence analysisAdd
BLAST
Transmembranei516 – 53621HelicalSequence analysisAdd
BLAST
Transmembranei540 – 56021HelicalSequence analysisAdd
BLAST
Transmembranei573 – 59321HelicalSequence analysisAdd
BLAST
Transmembranei623 – 64321HelicalSequence analysisAdd
BLAST
Transmembranei645 – 66521HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 711711Putative membrane protein ActII-3PRO_0000103581Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO5084.

Structurei

3D structure databases

ProteinModelPortaliQ53902.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105EYF. Bacteria.
COG2409. LUCA.
HOGENOMiHOG000072128.
InParanoidiQ53902.
KOiK06994.
OMAiGRWIFWP.
OrthoDBiEOG63NMDB.
PhylomeDBiQ53902.

Family and domain databases

InterProiIPR004869. MMPL_dom.
IPR000731. SSD.
[Graphical view]
PfamiPF03176. MMPL. 2 hits.
[Graphical view]
PROSITEiPS50156. SSD. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53902-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRTLLSWPG GRRLKWLVLA AWIGLLIVLQ PLAGKLGDVE SNDAAAWLPG
60 70 80 90 100
NAESTEVLEL SEKFQPADTS PTVIVYDRPS GITAADEAKA RADATHFADG
110 120 130 140 150
TGVVGEPYGP VRSDDGKALR TVVNVHLGKD GWEGLNAAAK DMRAIARPSA
160 170 180 190 200
PDGLGVHVTG PTGYAADSAE SFSSADFKLT LVTLLIVVTI LVVTYRSPLL
210 220 230 240 250
WLLPMISAGM SLVISQAIVY LLAKNAGLTV NAQTAMILTV LVLGAATDYA
260 270 280 290 300
LLLVARYREE LRRHEDRHEA MAVALRRAGP AIVASAATVA VSMLVLLLAA
310 320 330 340 350
LNSTKGLGPV CAVGVLVGLL SMMTLLPALL VIFGRWVFWP ARPKHGTEPD
360 370 380 390 400
VTRGLWSRIA RLVSGRPRAV WVTTSLLLGA VATLAVTLNA DGLQQKDGFK
410 420 430 440 450
TKPESVVGEE ILTRHFPAGS GEPMVVIAKG ASADQVHAAL ETVPGVIEVA
460 470 480 490 500
PPQVKDGLAY VEATLGAGAD SPAAMRSVTA ARETLARLDG AQARVGGSSA
510 520 530 540 550
VVHDMREASS RDRGLIIPVI LAVVFCILAL LLRALVAPLL LIASVVLSFF
560 570 580 590 600
TALGLAALFF NHVFDFAGAD SAFPLWVFVF LVALGVDYNI FLVTRIKEES
610 620 630 640 650
DRLGTRQGAL KGLTSTGGVI TAAGLVLAGT FAALATLPLV FIAELGFTVA
660 670 680 690 700
VGVLLDTMIV RSVLVTALTL DVGRWMWWPH PLARREDPSE DPAVSGMPDS
710
IDSEASTTAS R
Length:711
Mass (Da):74,863
Last modified:November 1, 1996 - v1
Checksum:iA5466BEDABEED1B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64683 Genomic DNA. Translation: AAA26691.1.
AL939122 Genomic DNA. Translation: CAC44197.1.
PIRiC40046.
RefSeqiNP_629234.1. NC_003888.3.
WP_011030047.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAC44197; CAC44197; CAC44197.
GeneIDi1100525.
KEGGisco:SCO5084.
PATRICi23740008. VBIStrCoe124346_5164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64683 Genomic DNA. Translation: AAA26691.1.
AL939122 Genomic DNA. Translation: CAC44197.1.
PIRiC40046.
RefSeqiNP_629234.1. NC_003888.3.
WP_011030047.1. NC_003888.3.

3D structure databases

ProteinModelPortaliQ53902.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO5084.

Protein family/group databases

TCDBi2.A.6.5.1. the resistance-nodulation-cell division (rnd) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC44197; CAC44197; CAC44197.
GeneIDi1100525.
KEGGisco:SCO5084.
PATRICi23740008. VBIStrCoe124346_5164.

Phylogenomic databases

eggNOGiENOG4105EYF. Bacteria.
COG2409. LUCA.
HOGENOMiHOG000072128.
InParanoidiQ53902.
KOiK06994.
OMAiGRWIFWP.
OrthoDBiEOG63NMDB.
PhylomeDBiQ53902.

Family and domain databases

InterProiIPR004869. MMPL_dom.
IPR000731. SSD.
[Graphical view]
PfamiPF03176. MMPL. 2 hits.
[Graphical view]
PROSITEiPS50156. SSD. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The act cluster contains regulatory and antibiotic export genes, direct targets for translational control by the bldA tRNA gene of Streptomyces."
    Fernandez-Moreno M.A., Caballero J.L., Hopwood D.A., Malpartida F.
    Cell 66:769-780(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiMMPLA_STRCO
AccessioniPrimary (citable) accession number: Q53902
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: November 11, 2015
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.