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Protein
Submitted name:

Serine protease

Gene
N/A
Organism
Streptomyces coelicolor
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Serine proteaseImported
OrganismiStreptomyces coelicolorImported
Taxonomic identifieri1902 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei381 – 40323HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333Sequence analysisAdd
BLAST
Chaini34 – 412379Sequence analysisPRO_5004248409Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO5722.

Structurei

3D structure databases

ProteinModelPortaliQ53863.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini77 – 331255Peptidase S8InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG41090GG. Bacteria.
COG1404. LUCA.

Family and domain databases

Gene3Di3.40.50.200. 1 hit.
InterProiIPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR023834. T7SS_pept_S8A_mycosin-1.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 2 hits.
PfamiPF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 1 hit.
TIGRFAMsiTIGR03921. T7SS_mycosin. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53863-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQQPLTKAPT LAAAVLLTAL STCAPSVPSG YSAVDMREPL RLAGSASCTF
60 70 80 90 100
PSEQQFKARP WLQRVLLDEL WQGTRKGKGV RVAVIDTGVD DDNPQLTDAV
110 120 130 140 150
DKAAGLDLLT KGKGGDPTHD EVGHGTKVAG IIAARPAEGT GFVGLAPGAT
160 170 180 190 200
VIPVRQNDAD SSGDSDSMAA AIRHAVAKGA DVVNISQDTT KPLAATSELA
210 220 230 240 250
EAVREALAQG VVVVASAGND GLDGKTKDTY PAAFEASVAV ASSDRNNERA
260 270 280 290 300
AFSQPGDFVG VAAPGVDIVS TVPGGGQCTD SGTSFSAPFV AGVAVLLKEK
310 320 330 340 350
YPDWTPAQIV TRIEQTAERS VNGHDDFVGW GVVDPVRAVQ EADSGRPPSS
360 370 380 390 400
PTPDPGVRSA EAPDVAPFSL AETPEERDRR YAVYGLSVGA VLVVLISGTG
410
VVLRDLRRRR RP
Length:412
Mass (Da):42,648
Last modified:October 1, 2002 - v2
Checksum:i031D6C538F7D700D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33176 Genomic DNA. Translation: AAA85224.2.
PIRiT42024.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U33176 Genomic DNA. Translation: AAA85224.2.
PIRiT42024.

3D structure databases

ProteinModelPortaliQ53863.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi100226.SCO5722.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG41090GG. Bacteria.
COG1404. LUCA.

Family and domain databases

Gene3Di3.40.50.200. 1 hit.
InterProiIPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR023834. T7SS_pept_S8A_mycosin-1.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 2 hits.
PfamiPF00082. Peptidase_S8. 1 hit.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 1 hit.
TIGRFAMsiTIGR03921. T7SS_mycosin. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Putative Streptomyces coelicolor serine protease gene."
    Piret J.M., Harasym M.
    Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ53863_STRCH
AccessioniPrimary (citable) accession number: Q53863
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: October 1, 2002
Last modified: May 11, 2016
This is version 70 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.