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Q53844 (RNC_SPICI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease 3

EC=3.1.26.3
Alternative name(s):
Ribonuclease III
Short name=RNase III
Gene names
Name:rnc
OrganismSpiroplasma citri
Taxonomic identifier2133 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesEntomoplasmatalesSpiroplasmataceaeSpiroplasma

Protein attributes

Sequence length248 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon By similarity. HAMAP-Rule MF_00104

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. HAMAP-Rule MF_00104

Cofactor

Mg2+ By similarity. HAMAP-Rule MF_00104

Subunit structure

Homodimer By similarity. HAMAP-Rule MF_00104

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00104.

Sequence similarities

Contains 1 DRBM (double-stranded RNA-binding) domain.

Contains 1 RNase III domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 248248Ribonuclease 3 HAMAP-Rule MF_00104
PRO_0000180431

Regions

Domain15 – 142128RNase III
Domain169 – 24072DRBM

Sites

Active site591 Potential
Active site1311 By similarity
Metal binding551Magnesium By similarity
Metal binding1281Magnesium By similarity
Metal binding1311Magnesium By similarity

Sequences

Sequence LengthMass (Da)Tools
Q53844 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 1A5A02EA1AD95D82

FASTA24828,931
        10         20         30         40         50         60 
MQFINKQSEQ LFIELKAFFK QYHVFIKERQ YYLEALTHNS YANEHNLSYT YQRMEFLGDA 

        70         80         90        100        110        120 
ILAKEISLYL FLSFPDKNEG EITNLRSKIV REGTLAELVR RMNWAPFLLL GKGEIKTKGY 

       130        140        150        160        170        180 
EKNRILADIY ESMIAALYLD LGEDVVRTFI NNTLIRMVSN PGFFDKIRDY KTELQEFLQA 

       190        200        210        220        230        240 
GDARTLEYKL IKESQPLEGN RVLYTVVAEI GGIRYGEGCG YTHKEAEQLA ARDALQKLAT 


KSKYHFEK 

« Hide

References

[1]"Spiroplasma citri virus SpV1: characterization of viral sequences present in the spiroplasmal host chromosome."
Bebear C.-M., Aullo P., Bove J.-M., Renaudin J.
Curr. Microbiol. 32:134-140(1996)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 27556 / NCPPB 2647 / R8A2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U28972 Genomic DNA. Translation: AAA84999.1.

3D structure databases

ProteinModelPortalQ53844.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.1520.10. 1 hit.
3.30.160.20. 1 hit.
HAMAPMF_00104. RNase_III.
InterProIPR014720. dsRNA-bd_dom.
IPR011907. RNase_III.
IPR000999. RNase_III_dom.
[Graphical view]
PANTHERPTHR11207. PTHR11207. 1 hit.
PfamPF00035. dsrm. 1 hit.
PF00636. Ribonuclease_3. 1 hit.
[Graphical view]
SMARTSM00358. DSRM. 1 hit.
SM00535. RIBOc. 1 hit.
[Graphical view]
SUPFAMSSF69065. SSF69065. 1 hit.
TIGRFAMsTIGR02191. RNaseIII. 1 hit.
PROSITEPS50137. DS_RBD. 1 hit.
PS00517. RNASE_3_1. 1 hit.
PS50142. RNASE_3_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNC_SPICI
AccessionPrimary (citable) accession number: Q53844
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families