Q53752 (Q53752_STRAU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Ribonuclease EMBL AAA26806.1
EC=3.1.4.8 EMBL AAA26806.1

Gene names

Name:

ribonuclease EMBL AAA26806.1

Organism

Streptomyces aureofaciens EMBL AAA26806.1

Taxonomic identifier

1894 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length	163 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Hydrolase EMBL AAA26806.1
Technical term	3D-structure PDB 3D4A PDB 3DGY PDB 3D5I PDB 3DH2 PDB 1PYL PDB 3D5G PDB 1PY3
Gene Ontology (GO)
Molecular_function	RNA binding Inferred from electronic annotation. Source: InterPro endoribonuclease activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	122	1	Proton donor/acceptor PDB 1PYL
	Active site	152	1	Proton donor/acceptor PDB 1PYL
	Site	133	1	Transition state stabilizer PDB 1PYL

Sequences

	Sequence		Length	Mass (Da)
	Q53752 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 22DFAB7FE8727F9A	FASTA	163	17,099
	10 20 30 40 50 60 MTRSKSPLVV GAVLILAVLA GVGYLLAGRG GSTHPKAAAS SAAAGTSAPK SSAPKPSPPA 70 80 90 100 110 120 GGAWTPADPA LADVCRTKLP SQAQDTLALI AKNGPYPYNR DGVVFENRES RLPKKGNGYY 130 140 150 160 HEFTVVTPGS NDRGTRRVVT GGYGEQYWSP DHYATFQEID PRC

References

[1]	Nazarov V., Sevcik J., Durcova G., Stanssens P. Submitted (MAR-1992) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: R8/26 EMBL AAA26806.1.
[2]	"Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2." Sevcik J., Dauter Z., Wilson K.S. Acta Crystallogr. D 60:1198-1204(2004) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS) OF 67-163, ACTIVE SITE.
[3]	"Structure of RNase Sa2 complexes with mononucleotides--new aspects of catalytic reaction and substrate recognition." Bauerova-Hlinkova V., Dvorsky R., Perecko D., Povazanec F., Sevcik J. FEBS J. 276:4156-4168(2009) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 67-163.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

M88615 Genomic DNA. Translation: AAA26806.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1PY3	X-ray	1.80	A/B/C	67-163	[»]
1PYL	X-ray	1.51	A/B	67-163	[»]
3D4A	X-ray	2.20	A/B/C	67-163	[»]
3D5G	X-ray	1.80	A/B/C	67-163	[»]
3D5I	X-ray	2.20	A/B/C	67-163	[»]
3DGY	X-ray	1.80	A/B/C	67-163	[»]
3DH2	X-ray	2.25	A/B/C/D	67-163	[»]

ProteinModelPortal

Q53752.

SMR

Q53752. Positions 69-163.

ModBase

Search...

Protein-protein interaction databases

MINT

MINT-7136090.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

3.10.450.30. 1 hit.

InterPro

IPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]

Pfam

PF00545. Ribonuclease. 1 hit.
[Graphical view]

SUPFAM

SSF53933. Ribonuclease/ribotoxin. 1 hit.

ProtoNet

Search...

Other

EvolutionaryTrace

Q53752.

Entry information

Entry name

Q53752_STRAU

Accession

Primary (citable) accession number: Q53752

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	March 6, 2013
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)