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Protein
Submitted name:

Ribonuclease

Gene

ribonuclease

Organism
Streptomyces aureofaciens
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. endoribonuclease activity Source: InterPro
  2. RNA binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
RibonucleaseImported (EC:3.1.4.8Imported)
Gene namesi
Name:ribonucleaseImported
OrganismiStreptomyces aureofaciensImported
Taxonomic identifieri1894 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Interactioni

Protein-protein interaction databases

MINTiMINT-7136090.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PY3X-ray1.80A/B/C67-163[»]
1PYLX-ray1.51A/B67-163[»]
3D4AX-ray2.20A/B/C67-163[»]
3D5GX-ray1.80A/B/C67-163[»]
3D5IX-ray2.20A/B/C67-163[»]
3DGYX-ray1.80A/B/C67-163[»]
3DH2X-ray2.25A/B/C/D67-163[»]
ProteinModelPortaliQ53752.
SMRiQ53752. Positions 69-163.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ53752.

Family & Domainsi

Family and domain databases

Gene3Di3.10.450.30. 1 hit.
InterProiIPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]
PfamiPF00545. Ribonuclease. 1 hit.
[Graphical view]
SUPFAMiSSF53933. SSF53933. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q53752-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTRSKSPLVV GAVLILAVLA GVGYLLAGRG GSTHPKAAAS SAAAGTSAPK
60 70 80 90 100
SSAPKPSPPA GGAWTPADPA LADVCRTKLP SQAQDTLALI AKNGPYPYNR
110 120 130 140 150
DGVVFENRES RLPKKGNGYY HEFTVVTPGS NDRGTRRVVT GGYGEQYWSP
160
DHYATFQEID PRC
Length:163
Mass (Da):17,099
Last modified:November 1, 1996 - v1
Checksum:i22DFAB7FE8727F9A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M88615 Genomic DNA. Translation: AAA26806.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M88615 Genomic DNA. Translation: AAA26806.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1PY3X-ray1.80A/B/C67-163[»]
1PYLX-ray1.51A/B67-163[»]
3D4AX-ray2.20A/B/C67-163[»]
3D5GX-ray1.80A/B/C67-163[»]
3D5IX-ray2.20A/B/C67-163[»]
3DGYX-ray1.80A/B/C67-163[»]
3DH2X-ray2.25A/B/C/D67-163[»]
ProteinModelPortaliQ53752.
SMRiQ53752. Positions 69-163.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

MINTiMINT-7136090.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ53752.

Family and domain databases

Gene3Di3.10.450.30. 1 hit.
InterProiIPR000026. Gua-sp_ribonuclease_N1/T1.
IPR016191. Ribonuclease/ribotoxin.
[Graphical view]
PfamiPF00545. Ribonuclease. 1 hit.
[Graphical view]
SUPFAMiSSF53933. SSF53933. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Nazarov V., Sevcik J., Durcova G., Stanssens P.
    Submitted (FEB-1992) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: R8/26Imported.
  2. "Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2."
    Sevcik J., Dauter Z., Wilson K.S.
    Acta Crystallogr. D 60:1198-1204(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.51 ANGSTROMS) OF 67-163, ACTIVE SITE.
  3. "Structure of RNase Sa2 complexes with mononucleotides--new aspects of catalytic reaction and substrate recognition."
    Bauerova-Hlinkova V., Dvorsky R., Perecko D., Povazanec F., Sevcik J.
    FEBS J. 276:4156-4168(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) OF 67-163, ACTIVE SITE.

Entry informationi

Entry nameiQ53752_STRAU
AccessioniPrimary (citable) accession number: Q53752
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 7, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.