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Q53728 (PLD_STRAT) Reviewed, UniProtKB/Swiss-Prot

Last modified May 31, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phospholipase D
EC=3.1.4.4
Alternative name(s):
Choline phosphatase
OrganismStreptomyces antibioticus
Taxonomic identifier1890 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Streptomycineae › Streptomycetaceae › Streptomyces

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

A phosphatidylcholine + H2O = choline + a phosphatidate.

Subcellular location

Secreted.

Sequence similarities

Contains 2 PLD phosphodiesterase domains.

Ontologies

Keywords
   Biological processLipid degradation
   Cellular componentSecreted
   DomainRepeat
Signal
   Molecular functionHydrolase
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Biological processlipid catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionNAPE-specific phospholipase D activity

Inferred from electronic annotation. Source: EC

phospholipase D activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 4747
Chain48 – 556509Phospholipase D
PRO_0000024657

Regions

Domain210 – 23728PLD phosphodiesterase 1
Domain484 – 51128PLD phosphodiesterase 2

Secondary structure

1 ................................................................................... 556
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q53728 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: B388F0BDC8C0A596

FASTA55658,932
        10         20         30         40         50         60 
MTSDQRPARL PTHKGKLLAP HRLHRLIPVS VALTTVCAAL PSSTAYAADT PPTPHLDAIE 

        70         80         90        100        110        120 
RSLRDTSPGL EGSVWQRTDG NRLDAPDGDP AGWLLQTPGC WGDAGCKDRA GTRRLLDKMT 

       130        140        150        160        170        180 
RNIADARHTV DISSLAPFPN GGFEDAVVDG LKAVVAAGHS PRVRILVGAA PIYHLNVVPS 

       190        200        210        220        230        240 
RYRDELIGKL GAAAGKVTLN VASMTTSKTS LSWNHSKLLV VDGKTAITGG INGWKDDYLD 

       250        260        270        280        290        300 
TAHPVSDVDM ALSGPAAASA GKYLDTLWDW TCRNASDPAK VWLATSNGAS CMPSMEQDEA 

       310        320        330        340        350        360 
GSAPAEPTGD VPVIAVGGLG VGIKESDPSS GYHPDLPTAP DTKCTVGLHD NTNADRDYDT 

       370        380        390        400        410        420 
VNPEENALRS LIASARSHVE ISQQDLNATC PPLPRYDIRT YDTLAGKLAA GVKVRIVVSD 

       430        440        450        460        470        480 
PANRGAVGSG GYSQIKSLDE ISDTLRTRLV ALTGDNEKAS RALCGNLQLA SFRSSDAAKW 

       490        500        510        520        530        540 
ADGKPYALHH KLVSVDDSAF YIGSKNLYPA WLQDFGYIVE SPAAAQQLKT ELLDPEWKYS 

       550 
QQAAATPAGC PARQAG

« Hide

References

[1]"Phospholipase D from Streptomyces antibioticus: cloning, sequencing, expression, and relationship to other phospholipases."
Iwasaki Y., Nakano H., Yamane T.
Appl. Microbiol. Biotechnol. 42:290-299(1994) [PubMed: 7765769] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D16444 Genomic DNA. Translation: BAA03913.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2ZE4X-ray2.50A48-556[»]
2ZE9X-ray2.30A48-556[»]
ProteinModelPortalQ53728.
SMRQ53728. Positions 51-551.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR001736. PLipase_D/transphosphatidylase.
[Graphical view]
SMARTSM00155. PLDc. 2 hits.
[Graphical view]
PROSITEPS50035. PLD. 2 hits.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePLD_STRAT
AccessionPrimary (citable) accession number: Q53728
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 31, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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