Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Phospholipase D

Gene
N/A
Organism
Streptomyces antibioticus
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

A phosphatidylcholine + H2O = choline + a phosphatidate.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Lipid degradation, Lipid metabolism

Enzyme and pathway databases

BRENDAi3.1.4.4. 5974.

Names & Taxonomyi

Protein namesi
Recommended name:
Phospholipase D (EC:3.1.4.4)
Alternative name(s):
Choline phosphatase
OrganismiStreptomyces antibioticus
Taxonomic identifieri1890 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 47Add BLAST47
ChainiPRO_000002465748 – 556Phospholipase DAdd BLAST509

Proteomic databases

PRIDEiQ53728.

Structurei

Secondary structure

1556
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi54 – 66Combined sources13
Helixi68 – 70Combined sources3
Turni72 – 74Combined sources3
Beta strandi75 – 83Combined sources9
Turni90 – 93Combined sources4
Beta strandi94 – 98Combined sources5
Helixi110 – 124Combined sources15
Beta strandi127 – 137Combined sources11
Helixi141 – 156Combined sources16
Beta strandi162 – 168Combined sources7
Helixi179 – 190Combined sources12
Helixi191 – 196Combined sources6
Beta strandi198 – 204Combined sources7
Turni208 – 211Combined sources4
Beta strandi212 – 214Combined sources3
Beta strandi218 – 221Combined sources4
Turni222 – 224Combined sources3
Beta strandi225 – 230Combined sources6
Helixi235 – 238Combined sources4
Beta strandi240 – 243Combined sources4
Beta strandi246 – 254Combined sources9
Helixi255 – 273Combined sources19
Helixi274 – 276Combined sources3
Turni278 – 280Combined sources3
Beta strandi281 – 286Combined sources6
Helixi295 – 300Combined sources6
Beta strandi309 – 317Combined sources9
Beta strandi321 – 323Combined sources3
Turni351 – 353Combined sources3
Helixi356 – 361Combined sources6
Helixi363 – 373Combined sources11
Beta strandi376 – 384Combined sources9
Turni390 – 392Combined sources3
Helixi398 – 409Combined sources12
Beta strandi413 – 418Combined sources6
Helixi421 – 423Combined sources3
Beta strandi426 – 429Combined sources4
Helixi439 – 453Combined sources15
Helixi456 – 466Combined sources11
Beta strandi467 – 471Combined sources5
Beta strandi474 – 479Combined sources6
Beta strandi491 – 495Combined sources5
Turni496 – 498Combined sources3
Beta strandi499 – 504Combined sources6
Beta strandi515 – 520Combined sources6
Helixi522 – 531Combined sources10
Helixi533 – 540Combined sources8
Helixi541 – 543Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ZE4X-ray2.50A48-556[»]
2ZE9X-ray2.30A48-556[»]
ProteinModelPortaliQ53728.
SMRiQ53728.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ53728.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini210 – 237PLD phosphodiesterase 1PROSITE-ProRule annotationAdd BLAST28
Domaini484 – 511PLD phosphodiesterase 2PROSITE-ProRule annotationAdd BLAST28

Sequence similaritiesi

Contains 2 PLD phosphodiesterase domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Signal

Family and domain databases

InterProiIPR025202. PLD-like_dom.
IPR001736. PLipase_D/transphosphatidylase.
[Graphical view]
PfamiPF13091. PLDc_2. 1 hit.
[Graphical view]
SMARTiSM00155. PLDc. 2 hits.
[Graphical view]
PROSITEiPS50035. PLD. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q53728-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTSDQRPARL PTHKGKLLAP HRLHRLIPVS VALTTVCAAL PSSTAYAADT
60 70 80 90 100
PPTPHLDAIE RSLRDTSPGL EGSVWQRTDG NRLDAPDGDP AGWLLQTPGC
110 120 130 140 150
WGDAGCKDRA GTRRLLDKMT RNIADARHTV DISSLAPFPN GGFEDAVVDG
160 170 180 190 200
LKAVVAAGHS PRVRILVGAA PIYHLNVVPS RYRDELIGKL GAAAGKVTLN
210 220 230 240 250
VASMTTSKTS LSWNHSKLLV VDGKTAITGG INGWKDDYLD TAHPVSDVDM
260 270 280 290 300
ALSGPAAASA GKYLDTLWDW TCRNASDPAK VWLATSNGAS CMPSMEQDEA
310 320 330 340 350
GSAPAEPTGD VPVIAVGGLG VGIKESDPSS GYHPDLPTAP DTKCTVGLHD
360 370 380 390 400
NTNADRDYDT VNPEENALRS LIASARSHVE ISQQDLNATC PPLPRYDIRT
410 420 430 440 450
YDTLAGKLAA GVKVRIVVSD PANRGAVGSG GYSQIKSLDE ISDTLRTRLV
460 470 480 490 500
ALTGDNEKAS RALCGNLQLA SFRSSDAAKW ADGKPYALHH KLVSVDDSAF
510 520 530 540 550
YIGSKNLYPA WLQDFGYIVE SPAAAQQLKT ELLDPEWKYS QQAAATPAGC

PARQAG
Length:556
Mass (Da):58,932
Last modified:November 1, 1996 - v1
Checksum:iB388F0BDC8C0A596
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D16444 Genomic DNA. Translation: BAA03913.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D16444 Genomic DNA. Translation: BAA03913.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ZE4X-ray2.50A48-556[»]
2ZE9X-ray2.30A48-556[»]
ProteinModelPortaliQ53728.
SMRiQ53728.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ53728.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi3.1.4.4. 5974.

Miscellaneous databases

EvolutionaryTraceiQ53728.

Family and domain databases

InterProiIPR025202. PLD-like_dom.
IPR001736. PLipase_D/transphosphatidylase.
[Graphical view]
PfamiPF13091. PLDc_2. 1 hit.
[Graphical view]
SMARTiSM00155. PLDc. 2 hits.
[Graphical view]
PROSITEiPS50035. PLD. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPLD_STRAT
AccessioniPrimary (citable) accession number: Q53728
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.