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Q53707

- Q53707_STAAU

UniProt

Q53707 - Q53707_STAAU

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Protein
Submitted name:

MecA PBP2' (penicillin binding protein 2')

Gene

mecA

Organism
Staphylococcus aureus
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Molecular functioni

  1. penicillin binding Source: InterPro

GO - Biological processi

  1. response to antibiotic Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
MecA PBP2' (penicillin binding protein 2')Imported
Submitted name:
PBP2AImported
Gene namesi
Name:mecAImported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

Pathology & Biotechi

Structurei

3D structure databases

ProteinModelPortaliQ53707.
SMRiQ53707. Positions 27-668.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di3.40.710.10. 1 hit.
InterProiIPR012338. Beta-lactam/transpept-like.
IPR007887. MecA_N.
IPR005311. PBP_dimer.
IPR001460. PCN-bd_Tpept.
[Graphical view]
PfamiPF05223. MecA_N. 1 hit.
PF03717. PBP_dimer. 1 hit.
PF00905. Transpeptidase. 1 hit.
[Graphical view]
SUPFAMiSSF56519. SSF56519. 1 hit.
SSF56601. SSF56601. 1 hit.

Sequencei

Sequence statusi: Complete.

Q53707-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKIKIVPLI LIVVVVGFGI YFYASKDKEI NNTIDAIEDK NFKQVYKDSS
60 70 80 90 100
YISKSDNGEV EMTERPIKIY NSLGVKDINI QDRKIKKVSK NKKRVDAQYK
110 120 130 140 150
IKTNYGNIDR NVQFNFVKED GMWKLDWDHS VIIPGMQKDQ SIHIENLKSE
160 170 180 190 200
RGKILDRNNV ELANTGTHMR LGIVPKNVSK KDYKAIAKEL SISEDYINNK
210 220 230 240 250
WIKIGYKMIP SFHFKTVKKM DEYLSDFAKK FHLTTNETES RNYPLEKATS
260 270 280 290 300
HLLGYVGPIN SEELKQKEYK GYKDDAVIGK KGLEKLYDKK LQHEDGYRVT
310 320 330 340 350
IVDDNSNTIA HTLIEKKKKD GKDIQLTIDA KVQKSIYNNM KNDYGSGTAI
360 370 380 390 400
HPQTGELLAL VSTPSYDVYP FMYGMSNEEY NKLTEDKKEP LLNKFQITTS
410 420 430 440 450
PGSTQKILTA MIGLNNKTLD DKTSYKIDGK GWQKDKSWGG YNVTRYEVVN
460 470 480 490 500
GNIDLKQAIE SSDNIFFARV ALELGSKKFE KGMKKLGVGE DIPSDYPFYN
510 520 530 540 550
AQISNKNLDN EILLADSGYG QGEILINPVQ ILSIYSALEN NGNINAPHLL
560 570 580 590 600
KDTKNKVWKK NIISKENINL LNDGMQQVVN KTHKEDIYRS YANLIGKSGT
610 620 630 640 650
AELKMKQGES GRQIGWFISY DKDNPNMMMA INVKDVQDKG MASYNAKISG
660
KVYDELYENG NKKYDIDE
Length:668
Mass (Da):76,266
Last modified:November 1, 1996 - v1
Checksum:i5E58F2572B359EEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52593 Genomic DNA. Translation: CAA36829.1.
Y14051 Genomic DNA. Translation: CAA74376.1.
PIRiJQ0773.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52593 Genomic DNA. Translation: CAA36829.1 .
Y14051 Genomic DNA. Translation: CAA74376.1 .
PIRi JQ0773.

3D structure databases

ProteinModelPortali Q53707.
SMRi Q53707. Positions 27-668.
ModBasei Search...
MobiDBi Search...

Chemistry

ChEMBLi CHEMBL3512.
DrugBanki DB01332. Ceftizoxime.
DB01603. Meticillin.
DB00417. Penicillin V.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.710.10. 1 hit.
InterProi IPR012338. Beta-lactam/transpept-like.
IPR007887. MecA_N.
IPR005311. PBP_dimer.
IPR001460. PCN-bd_Tpept.
[Graphical view ]
Pfami PF05223. MecA_N. 1 hit.
PF03717. PBP_dimer. 1 hit.
PF00905. Transpeptidase. 1 hit.
[Graphical view ]
SUPFAMi SSF56519. SSF56519. 1 hit.
SSF56601. SSF56601. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Sequence comparison of mecA genes isolated from methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis."
    Ryffel C., Tesch W., Birch-Machin I., Reynolds P.E., Barberis-Maino L., Kayser F.H., Berger-Bachi B.
    Gene 94:137-138(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: NCTC8325Imported.
  2. "Genetic organization of the mecA region in methicillin-susceptible and methicillin-resistant strains of Staphylococcus sciuri."
    Wu S., de Lencastre H., Tomasz A.
    J. Bacteriol. 180:236-242(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BB270Imported and BMS-1Imported.

Entry informationi

Entry nameiQ53707_STAAU
AccessioniPrimary (citable) accession number: Q53707
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)