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Protein
Submitted name:

MecA PBP2' (penicillin binding protein 2')

Gene

mecA

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
MecA PBP2' (penicillin binding protein 2')Imported
Submitted name:
PBP2AImported
Gene namesi
Name:mecAImported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 24HelicalSequence analysisAdd BLAST18

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL3512
DrugBankiDB01332 Ceftizoxime
DB01603 Meticillin
DB00417 Phenoxymethylpenicillin

Structurei

3D structure databases

ProteinModelPortaliQ53707
SMRiQ53707
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 140MecA_NInterPro annotationAdd BLAST115
Domaini148 – 309PBP_dimerInterPro annotationAdd BLAST162
Domaini346 – 657TranspeptidaseInterPro annotationAdd BLAST312

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4107RVG Bacteria
COG0768 LUCA

Family and domain databases

InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR007887 MecA_N
IPR032710 NTF2-like_dom_sf
IPR005311 PBP_dimer
IPR036138 PBP_dimer_sf
IPR001460 PCN-bd_Tpept
PfamiView protein in Pfam
PF05223 MecA_N, 1 hit
PF03717 PBP_dimer, 1 hit
PF00905 Transpeptidase, 1 hit
SUPFAMiSSF54427 SSF54427, 1 hit
SSF56519 SSF56519, 1 hit
SSF56601 SSF56601, 1 hit

Sequencei

Sequence statusi: Complete.

Q53707-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKIKIVPLI LIVVVVGFGI YFYASKDKEI NNTIDAIEDK NFKQVYKDSS
60 70 80 90 100
YISKSDNGEV EMTERPIKIY NSLGVKDINI QDRKIKKVSK NKKRVDAQYK
110 120 130 140 150
IKTNYGNIDR NVQFNFVKED GMWKLDWDHS VIIPGMQKDQ SIHIENLKSE
160 170 180 190 200
RGKILDRNNV ELANTGTHMR LGIVPKNVSK KDYKAIAKEL SISEDYINNK
210 220 230 240 250
WIKIGYKMIP SFHFKTVKKM DEYLSDFAKK FHLTTNETES RNYPLEKATS
260 270 280 290 300
HLLGYVGPIN SEELKQKEYK GYKDDAVIGK KGLEKLYDKK LQHEDGYRVT
310 320 330 340 350
IVDDNSNTIA HTLIEKKKKD GKDIQLTIDA KVQKSIYNNM KNDYGSGTAI
360 370 380 390 400
HPQTGELLAL VSTPSYDVYP FMYGMSNEEY NKLTEDKKEP LLNKFQITTS
410 420 430 440 450
PGSTQKILTA MIGLNNKTLD DKTSYKIDGK GWQKDKSWGG YNVTRYEVVN
460 470 480 490 500
GNIDLKQAIE SSDNIFFARV ALELGSKKFE KGMKKLGVGE DIPSDYPFYN
510 520 530 540 550
AQISNKNLDN EILLADSGYG QGEILINPVQ ILSIYSALEN NGNINAPHLL
560 570 580 590 600
KDTKNKVWKK NIISKENINL LNDGMQQVVN KTHKEDIYRS YANLIGKSGT
610 620 630 640 650
AELKMKQGES GRQIGWFISY DKDNPNMMMA INVKDVQDKG MASYNAKISG
660
KVYDELYENG NKKYDIDE
Length:668
Mass (Da):76,266
Last modified:November 1, 1996 - v1
Checksum:i5E58F2572B359EEA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X52593 Genomic DNA Translation: CAA36829.1
Y14051 Genomic DNA Translation: CAA74376.1
PIRiJQ0773

Similar proteinsi

Entry informationi

Entry nameiQ53707_STAAU
AccessioniPrimary (citable) accession number: Q53707
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health