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Q53707

- Q53707_STAAU

UniProt

Q53707 - Q53707_STAAU

Protein
Submitted name:

MecA PBP2' (penicillin binding protein 2')

Gene

mecA

Organism
Staphylococcus aureus
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. penicillin binding Source: InterPro

    GO - Biological processi

    1. response to antibiotic Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MecA PBP2' (penicillin binding protein 2')Imported
    Submitted name:
    PBP2AImported
    Gene namesi
    Name:mecAImported
    OrganismiStaphylococcus aureusImported
    Taxonomic identifieri1280 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus

    Pathology & Biotechi

    Structurei

    3D structure databases

    ProteinModelPortaliQ53707.
    SMRiQ53707. Positions 27-668.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Family and domain databases

    Gene3Di3.40.710.10. 1 hit.
    InterProiIPR012338. Beta-lactam/transpept-like.
    IPR007887. MecA_N.
    IPR005311. PBP_dimer.
    IPR001460. PCN-bd_Tpept.
    [Graphical view]
    PfamiPF05223. MecA_N. 1 hit.
    PF03717. PBP_dimer. 1 hit.
    PF00905. Transpeptidase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56519. SSF56519. 1 hit.
    SSF56601. SSF56601. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q53707-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKKIKIVPLI LIVVVVGFGI YFYASKDKEI NNTIDAIEDK NFKQVYKDSS    50
    YISKSDNGEV EMTERPIKIY NSLGVKDINI QDRKIKKVSK NKKRVDAQYK 100
    IKTNYGNIDR NVQFNFVKED GMWKLDWDHS VIIPGMQKDQ SIHIENLKSE 150
    RGKILDRNNV ELANTGTHMR LGIVPKNVSK KDYKAIAKEL SISEDYINNK 200
    WIKIGYKMIP SFHFKTVKKM DEYLSDFAKK FHLTTNETES RNYPLEKATS 250
    HLLGYVGPIN SEELKQKEYK GYKDDAVIGK KGLEKLYDKK LQHEDGYRVT 300
    IVDDNSNTIA HTLIEKKKKD GKDIQLTIDA KVQKSIYNNM KNDYGSGTAI 350
    HPQTGELLAL VSTPSYDVYP FMYGMSNEEY NKLTEDKKEP LLNKFQITTS 400
    PGSTQKILTA MIGLNNKTLD DKTSYKIDGK GWQKDKSWGG YNVTRYEVVN 450
    GNIDLKQAIE SSDNIFFARV ALELGSKKFE KGMKKLGVGE DIPSDYPFYN 500
    AQISNKNLDN EILLADSGYG QGEILINPVQ ILSIYSALEN NGNINAPHLL 550
    KDTKNKVWKK NIISKENINL LNDGMQQVVN KTHKEDIYRS YANLIGKSGT 600
    AELKMKQGES GRQIGWFISY DKDNPNMMMA INVKDVQDKG MASYNAKISG 650
    KVYDELYENG NKKYDIDE 668
    Length:668
    Mass (Da):76,266
    Last modified:November 1, 1996 - v1
    Checksum:i5E58F2572B359EEA
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52593 Genomic DNA. Translation: CAA36829.1.
    Y14051 Genomic DNA. Translation: CAA74376.1.
    PIRiJQ0773.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X52593 Genomic DNA. Translation: CAA36829.1 .
    Y14051 Genomic DNA. Translation: CAA74376.1 .
    PIRi JQ0773.

    3D structure databases

    ProteinModelPortali Q53707.
    SMRi Q53707. Positions 27-668.
    ModBasei Search...
    MobiDBi Search...

    Chemistry

    ChEMBLi CHEMBL2363021.
    DrugBanki DB01332. Ceftizoxime.
    DB01603. Meticillin.
    DB00417. Penicillin V.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.710.10. 1 hit.
    InterProi IPR012338. Beta-lactam/transpept-like.
    IPR007887. MecA_N.
    IPR005311. PBP_dimer.
    IPR001460. PCN-bd_Tpept.
    [Graphical view ]
    Pfami PF05223. MecA_N. 1 hit.
    PF03717. PBP_dimer. 1 hit.
    PF00905. Transpeptidase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56519. SSF56519. 1 hit.
    SSF56601. SSF56601. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence comparison of mecA genes isolated from methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis."
      Ryffel C., Tesch W., Birch-Machin I., Reynolds P.E., Barberis-Maino L., Kayser F.H., Berger-Bachi B.
      Gene 94:137-138(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: NCTC8325Imported.
    2. "Genetic organization of the mecA region in methicillin-susceptible and methicillin-resistant strains of Staphylococcus sciuri."
      Wu S., de Lencastre H., Tomasz A.
      J. Bacteriol. 180:236-242(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BB270Imported and BMS-1Imported.

    Entry informationi

    Entry nameiQ53707_STAAU
    AccessioniPrimary (citable) accession number: Q53707
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 1, 1996
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)