Q53707 (Q53707_STAAU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
MecA PBP2' (penicillin binding protein 2') EMBL CAA36829.1

Submitted name:
PBP2A EMBL CAA74376.1

Gene names

Name:

mecA EMBL CAA74376.1

Organism

Staphylococcus aureus EMBL CAA36829.1

Taxonomic identifier

1280 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	668 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Gene Ontology (GO)
Biological process	peptidoglycan-based cell wall biogenesis Inferred from electronic annotation. Source: InterPro response to antibiotic Inferred from electronic annotation. Source: InterPro
Molecular function	penicillin binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q53707 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 5E58F2572B359EEA	FASTA	668	76,266
	10 20 30 40 50 60 MKKIKIVPLI LIVVVVGFGI YFYASKDKEI NNTIDAIEDK NFKQVYKDSS YISKSDNGEV 70 80 90 100 110 120 EMTERPIKIY NSLGVKDINI QDRKIKKVSK NKKRVDAQYK IKTNYGNIDR NVQFNFVKED 130 140 150 160 170 180 GMWKLDWDHS VIIPGMQKDQ SIHIENLKSE RGKILDRNNV ELANTGTHMR LGIVPKNVSK 190 200 210 220 230 240 KDYKAIAKEL SISEDYINNK WIKIGYKMIP SFHFKTVKKM DEYLSDFAKK FHLTTNETES 250 260 270 280 290 300 RNYPLEKATS HLLGYVGPIN SEELKQKEYK GYKDDAVIGK KGLEKLYDKK LQHEDGYRVT 310 320 330 340 350 360 IVDDNSNTIA HTLIEKKKKD GKDIQLTIDA KVQKSIYNNM KNDYGSGTAI HPQTGELLAL 370 380 390 400 410 420 VSTPSYDVYP FMYGMSNEEY NKLTEDKKEP LLNKFQITTS PGSTQKILTA MIGLNNKTLD 430 440 450 460 470 480 DKTSYKIDGK GWQKDKSWGG YNVTRYEVVN GNIDLKQAIE SSDNIFFARV ALELGSKKFE 490 500 510 520 530 540 KGMKKLGVGE DIPSDYPFYN AQISNKNLDN EILLADSGYG QGEILINPVQ ILSIYSALEN 550 560 570 580 590 600 NGNINAPHLL KDTKNKVWKK NIISKENINL LNDGMQQVVN KTHKEDIYRS YANLIGKSGT 610 620 630 640 650 660 AELKMKQGES GRQIGWFISY DKDNPNMMMA INVKDVQDKG MASYNAKISG KVYDELYENG NKKYDIDE

References

[1]	"Sequence comparison of mecA genes isolated from methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis." Ryffel C., Tesch W., Birch-Machin I., Reynolds P.E., Barberis-Maino L., Kayser F.H., Berger-Bachi B. Gene 94:137-138(1990) [PubMed: 2227446] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: NCTC8325 EMBL CAA36829.1.
[2]	"Genetic organization of the mecA region in methicillin-susceptible and methicillin-resistant strains of Staphylococcus sciuri." Wu S., de Lencastre H., Tomasz A. J. Bacteriol. 180:236-242(1998) [PubMed: 9440511] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: BB270 EMBL CAA74376.1 and BMS-1 EMBL CAA74376.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X52593 Genomic DNA. Translation: CAA36829.1. Y14051 Genomic DNA. Translation: CAA74376.1.
PIR	JQ0773.
3D structure databases
HSSP	HSSP built from PDB template 1MWX based on UniProtKB Q93IC2.
ProteinModelPortal	Q53707.
SMR	Q53707. Positions 27-668.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR012338. Beta-lactam/transpept-like. IPR007887. MecA_N. IPR005311. PBP_dimer. IPR001460. PCN-bd_Tpept. [Graphical view]
Gene3D	G3DSA:3.40.710.10. G3DSA:3.40.710.10. 1 hit.
Pfam	PF05223. MecA_N. 1 hit. PF03717. PBP_dimer. 1 hit. PF00905. Transpeptidase. 1 hit. [Graphical view]
SUPFAM	SSF56519. PBP_dimer. 1 hit. SSF56601. PBP_transp_fold. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q53707_STAAU

Accession

Primary (citable) accession number: Q53707

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	April 5, 2011
This is version 42 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)