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Q53685 (OLED_STRAT) Reviewed, UniProtKB/Swiss-Prot

Last modified March 8, 2011. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Oleandomycin glycosyltransferase

EC=2.4.1.-
Gene names
Name:oleD
Synonyms:UGT102A2
OrganismStreptomyces antibioticus
Taxonomic identifier1890 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

Protein attributes

Sequence length430 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Specifically inactivates oleandomycin via 2'-O-glycosylation using UDP-glucose.

Sequence similarities

Belongs to the UDP-glycosyltransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 430430Oleandomycin glycosyltransferase
PRO_0000074165

Secondary structure

........................................................................ 430
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q53685 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 320512217B42A0B7

FASTA43047,136
        10         20         30         40         50         60 
MTTQTTPAHI AMFSIAAHGH VNPSLEVIRE LVARGHRVTY AIPPVFADKV AATGPRPVLY 

        70         80         90        100        110        120 
HSTLPGPDAD PEAWGSTLLD NRRTFLNDAI QALPQLADAY ADDIPDLVLH DITSYPARVL 

       130        140        150        160        170        180 
ARRWGVPAVS LSPNLVAWKG YEEEVAEPMW REPRQTERGR AYYARFEAWL KENGITEHPD 

       190        200        210        220        230        240 
TFASHPPRSL VLIPKALQPH ADRVDEDVYT FVGACQGDRA EEGGWQRPAG AEKVVLVSLG 

       250        260        270        280        290        300 
SAFTKQPAFY RECVRAFGNL PGWHLVLQIG RKVTPAELGE LPDNVEVHDW VPQLAILRQA 

       310        320        330        340        350        360 
DLFVTHAGAG GSQEGLATAT PMIAVPQAVD QFGNADMLQG LGVARKLATE EATADLLRET 

       370        380        390        400        410        420 
ALALVDDPEV ARRLRRIQAE MAQEGGTRRA ADLIEAELPA RHERQEPVGD RPNVGDRPAG 

       430 
VRSDRQRSAL 

« Hide

References

[1]"Characterization of a Streptomyces antibioticus gene cluster encoding a glycosyltransferase involved in oleandomycin inactivation."
Hernandez C., Olano C., Mendez C., Salas J.A.
Gene 134:139-140(1993) [PubMed: 8244027] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 11891 / DSM 40868 / NCIB 11506.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z22577 Genomic DNA. Translation: CAA80301.1.
PIRS33184.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2IYFX-ray1.70A/B1-430[»]
ProteinModelPortalQ53685.
SMRQ53685. Positions 6-399.
ModBaseSearch...

Protein family/group databases

CAZyGT1. Glycosyltransferase Family 1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004276. Glyco_trans_28.
IPR002213. UDP_glucos_trans.
IPR006326. UDPGT_MGT.
[Graphical view]
PANTHERPTHR11926. UDP_glucos_trans. 1 hit.
PfamPF03033. Glyco_transf_28. 1 hit.
PF00201. UDPGT. 1 hit.
[Graphical view]
TIGRFAMsTIGR01426. MGT. 1 hit.
PROSITEPS00375. UDPGT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameOLED_STRAT
AccessionPrimary (citable) accession number: Q53685
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 8, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families