Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q53552 (NHG2_PSEPU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Salicylate hydroxylase

EC=1.14.13.1
Alternative name(s):
Salicylate 1-monooxygenase
Gene names
Name:nahG
OrganismPseudomonas putida (Arthrobacter siderocapsulatus)
Taxonomic identifier303 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length435 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

Salicylate + NADH + O2 = catechol + NAD+ + H2O + CO2.

Cofactor

FAD.

Pathway

Aromatic compound metabolism; naphthalene degradation.

Ontologies

Keywords
   Biological processAromatic hydrocarbons catabolism
   LigandFAD
Flavoprotein
NAD
   Molecular functionMonooxygenase
Oxidoreductase
   Technical termPlasmid
Gene Ontology (GO)
   Biological_processaromatic compound catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionsalicylate 1-monooxygenase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 435435Salicylate hydroxylase
PRO_0000096804

Regions

Nucleotide binding12 – 4130FAD Potential

Sequences

Sequence LengthMass (Da)Tools
Q53552 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 7E8017520726DD8C

FASTA43547,914
        10         20         30         40         50         60 
MNDMNAKKPA LRVAIVGGGI SGLALALSLC KHSHLNVQLF EAAPAFGEVG AGVSFGPNAV 

        70         80         90        100        110        120 
RAIVGLGLGQ AYFQVADRTP QPWEDIWFEW RRGSDASYLG ATIAGVGQSS VHRADFLDAL 

       130        140        150        160        170        180 
VKHLPEGIAQ FRKRATQIEQ QGDELQVLFR DGTEYRCDLL IGRDGIKSAL RSYVLEGQGQ 

       190        200        210        220        230        240 
DHLEPRFSGT CAYRGMVDSL QLREAYRING IDEHLVDVPQ MYLGLYGHIL TFPVRKGRIV 

       250        260        270        280        290        300 
NVVAFTSDRS QPEPTWPADA PWVREASQRE MLDAFAGWGD ARALLECIPA PTLWALHDLP 

       310        320        330        340        350        360 
ELPGYVHGRV ALIGDAAHAM LPHQGAGAGQ GLEDAYFLAR LLGDSRTETG NLPELLGAYD 

       370        380        390        400        410        420 
DLRRPHACRV QRTTVETGEL YELRDPIVGA DEQLVGEILA TRFDWLWNHD LDADVAEARL 

       430 
RMGWEAHEQI ALRQG 

« Hide

References

[1]"Nucleotide sequence of salicylate hydroxylase gene and its 5'-flanking region of Pseudomonas putida KF715."
Lee J., Oh J., Min K.R., Kim Y.
Biochem. Biophys. Res. Commun. 218:544-548(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: KF715.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
S80995 Genomic DNA. Translation: AAB35960.1.
PIRJC4590.

3D structure databases

ProteinModelPortalQ53552.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00082.

Family and domain databases

InterProIPR002938. mOase_FAD-bd.
IPR003042. Rng_hydrolase-like.
IPR017631. Salicylate_mOase.
[Graphical view]
PfamPF01494. FAD_binding_3. 1 hit.
[Graphical view]
PRINTSPR00420. RNGMNOXGNASE.
TIGRFAMsTIGR03219. salicylate_mono. 1 hit.
ProtoNetSearch...

Entry information

Entry nameNHG2_PSEPU
AccessionPrimary (citable) accession number: Q53552
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1996
Last modified: October 16, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways