Reviewed,
UniProtKB/Swiss-Prot Q53479 (IDSA_METTM)
Last modified
November 25, 2008.
Version 43.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Bifunctional short chain isoprenyl diphosphate synthase Including the following 2 domains: 1- Recommended name: Farnesyl pyrophosphate synthetase Short name=FPP synthetase EC=2.5.1.1 Alternative name(s): Dimethylallyltranstransferase 2- Recommended name: Geranyltranstransferase EC=2.5.1.10 | ||
| Gene names |
| ||
| Organism | Methanobacterium thermoautotrophicum (strain Marburg / DSM 2133) | ||
| Taxonomic identifier | 79929 [NCBI] | ||
| Taxonomic lineage | Archaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter |
Protein attributes
| Sequence length | 325 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Catalytic activity | Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate. Geranyl diphosphate + isopentenyl diphosphate = diphosphate + trans,trans-farnesyl diphosphate. |
| Cofactor | Magnesium. |
| Subunit structure | Homodimer. |
| Subcellular location | |
| Sequence similarities | Belongs to the FPP/GGPP synthetase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Isoprene biosynthesis Lipid synthesis |
| Cellular component | Cytoplasm |
| Ligand | Magnesium |
| Molecular function | Transferase |
| Technical term | Direct protein sequencing Multifunctional enzyme |
Gene Ontology (GO) | |
| Biological process | isoprenoid biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | dimethylallyltranstransferase activity Inferred from electronic annotation. Source: EC geranyltranstransferase activityInferred from electronic annotation. Source: EC magnesium ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Isolation and characterization of idsA: the gene for the short chain isoprenyl diphosphate synthase from Methanobacterium thermoautotrophicum." Chen A., Poulter C.D. Arch. Biochem. Biophys. 314:399-404(1994) [PubMed: 7979381] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE. |
Cross-references
Sequence databases | |
|---|---|
| S75695 Genomic DNA. Translation: AAB32421.1. | |
3D structure databases | |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR000092. Polyprenyl_synt. IPR017446. Polyprenyl_synth-rel. [Graphical view] |
| PANTHER | PTHR12001. Polyprenyl_synt. 1 hit. |
| Pfam | PF00348. polyprenyl_synt. 1 hit. [Graphical view] |
| PROSITE | PS00723. POLYPRENYL_SYNTHET_1. 1 hit. PS00444. POLYPRENYL_SYNTHET_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | IDSA_METTM | ||||||||
| Accession | Primary (citable) accession number: Q53479 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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