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Q53479 (IDSA_METTM) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Short chain isoprenyl diphosphate synthase
EC=2.5.1.-
Gene names
Name:idsA
Ordered Locus Names:MTBMA_c05390
OrganismMethanothermobacter marburgensis (strain DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium thermoautotrophicum) [Complete proteome] [HAMAP]
Taxonomic identifier79929 [NCBI]
Taxonomic lineageArchaea › Euryarchaeota › Methanobacteria › Methanobacteriales › Methanobacteriaceae › Methanothermobacter ›

Protein attributes

Sequence length325 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Cofactor

Binds 3 magnesium ions per subunit By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the FPP/GGPP synthase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionTransferase
   Technical termComplete proteome
Direct protein sequencing
Gene Ontology (GO)
   Biological_processisoprenoid biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

transferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed
Chain2 – 325324Short chain isoprenyl diphosphate synthase
PRO_0000123972

Sites

Metal binding831Magnesium 1 By similarity
Metal binding831Magnesium 2 By similarity
Metal binding871Magnesium 1 By similarity
Metal binding871Magnesium 2 By similarity
Metal binding2141Magnesium 3 By similarity
Binding site441Isopentenyl diphosphate By similarity
Binding site471Isopentenyl diphosphate By similarity
Binding site761Isopentenyl diphosphate By similarity
Binding site921Allylic substrate By similarity
Binding site931Isopentenyl diphosphate By similarity
Binding site1731Isopentenyl By similarity
Binding site1741Allylic substrate By similarity
Binding site2111Allylic substrate By similarity
Binding site2281Allylic substrate By similarity
Binding site2381Allylic substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q53479 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: D28CAFF56EBE27E9

FASTA32535,636
        10         20         30         40         50         60 
MTEVLDILRK YSEVADKRIM ECISDITPDT LLKASEHLIT AGGKKIRPSL ALLSCEAVGG 

        70         80         90        100        110        120 
NPEDAAGVAA AIELIHTFSL IHDDIMDDDE MRRGEPSVHV IWGEPMAILA GDVLFSKAFE 

       130        140        150        160        170        180 
AVIRNGDSER VKDALAVVVD SCVKICEGQA LDMGFEERLD VTEDEYMEMI YKKTAALIAA 

       190        200        210        220        230        240 
ATKAGAIMGG ASEREVEALE DYGKFIGLAF QIHDDYLDVV SDEESLGKPV GSDIAEGKMT 

       250        260        270        280        290        300 
LMVVKALEEA SEEDRERLIS ILGSGDEGSV AEAIEIFERY GATQYAHEVA LDYVRMAKER 

       310        320 
LEILEDSDAR DALMRIADFV LEREH

« Hide

References

« Hide 'large scale' references
[1]"Isolation and characterization of idsA: the gene for the short chain isoprenyl diphosphate synthase from Methanobacterium thermoautotrophicum."
Chen A., Poulter C.D.
Arch. Biochem. Biophys. 314:399-404(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.
[2]"Complete genome sequence of Methanothermobacter marburgensis, a methanoarchaeon model organism."
Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H., Gottschalk G., Thauer R.K.
J. Bacteriol. 192:5850-5851(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 2133 / 14651 / NBRC 100331 / OCM 82 / Marburg.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		S75695 Genomic DNA. Translation: AAB32421.1.
CP001710 Genomic DNA. Translation: ADL58134.1.
RefSeqYP_003849447.1. NC_014408.1.

3D structure databases

ProteinModelPortalQ53479.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADL58134; ADL58134; MTBMA_c05390.
GeneID9704247.
KEGGmmg:MTBMA_c05390.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000009101.
KOK13787.
OMAESIHERK.
ProtClustDBCLSK797822.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-14627.
MMAR79929:GH5J-546-MONOMER.

Family and domain databases

Gene3D1.10.600.10. 1 hit.
InterProIPR000092. Polyprenyl_synt.
IPR017446. Polyprenyl_synth-rel.
IPR008949. Terpenoid_synth.
[Graphical view]
PANTHERPTHR12001. PTHR12001. 1 hit.
PfamPF00348. polyprenyl_synt. 1 hit.
[Graphical view]
SUPFAMSSF48576. Terpenoid_synth. 1 hit.
PROSITEPS00723. POLYPRENYL_SYNTHASE_1. 1 hit.
PS00444. POLYPRENYL_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIDSA_METTM
AccessionPrimary (citable) accession number: Q53479
Secondary accession number(s): D9PV86
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: May 1, 2013
This is version 68 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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