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Protein
Submitted name:

Multidrug MFS transporter

Gene

norA

Organism
Staphylococcus aureus
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Multidrug MFS transporterImported
Submitted name:
NorAImported
Submitted name:
Transporter, major facilitator family proteinImported
Gene namesi
Name:norAImported
Synonyms:tetAImported
ORF Names:A4U86_00010Imported, A7J36_06730Imported, ERS072738_00276Imported, ERS074020_00271Imported, ERS1058648_00400Imported, HMPREF3211_00604Imported
OrganismiStaphylococcus aureusImported
Taxonomic identifieri1280 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000077578 Componenti: Unassembled WGS sequence
  • UP000071995 Componenti: Unassembled WGS sequence
  • UP000070177 Componenti: Unassembled WGS sequence
  • UP000072664 Componenti: Unassembled WGS sequence
  • UP000078523 Componenti: Unassembled WGS sequence
  • UP000073331 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 30HelicalSequence analysisAdd BLAST24
Transmembranei42 – 62HelicalSequence analysisAdd BLAST21
Transmembranei69 – 87HelicalSequence analysisAdd BLAST19
Transmembranei99 – 117HelicalSequence analysisAdd BLAST19
Transmembranei129 – 151HelicalSequence analysisAdd BLAST23
Transmembranei157 – 178HelicalSequence analysisAdd BLAST22
Transmembranei199 – 220HelicalSequence analysisAdd BLAST22
Transmembranei240 – 259HelicalSequence analysisAdd BLAST20
Transmembranei271 – 289HelicalSequence analysisAdd BLAST19
Transmembranei295 – 317HelicalSequence analysisAdd BLAST23
Transmembranei329 – 351HelicalSequence analysisAdd BLAST23
Transmembranei357 – 375HelicalSequence analysisAdd BLAST19

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Interactioni

Protein-protein interaction databases

STRINGi93062.SACOL0754.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini4 – 380MFSInterPro annotationAdd BLAST377

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105DP8. Bacteria.
ENOG410XQPT. LUCA.
KOiK19576.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004734. Multidrug-R.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00880. 2_A_01_02. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53459-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNKQIFVLYF NIFLIFLGIG LVIPVLPVYL KDLGLTGSDL GLLVAAFALS
60 70 80 90 100
QMIISPFGGT LADKLGKKLI ICIGLILFSV SEFMFAVGHN FSVLMLSRVI
110 120 130 140 150
GGMSAGMVMP GVTGLIADIS PSHQKAKNFG YMSAIINSGF ILGPGIGGFM
160 170 180 190 200
AEVSHRMPFY FAGALGILAF IMSIVLIHDP KKSTTSGFQK LEPQLLTKIN
210 220 230 240 250
WKVFITPVIL TLVLSFGLSA FETLYSLYTA DKVNYSPKDI SIAITGGGIF
260 270 280 290 300
GALFQIYFFD KFMKYFSELT FIAWSLLYSV VVLILLVFAN DYWSIMLISF
310 320 330 340 350
VVFIGFDMIR PAITNYFSNI AGERQGFAGG LNSTFTSMGN FIGPLIAGAL
360 370 380
FDVHIEAPIY MAIGVSLAGV VIVLIEKQHR AKLKEQNM
Length:388
Mass (Da):42,324
Last modified:November 1, 1996 - v1
Checksum:i6C63883817827EA8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S74031 Genomic DNA. Translation: AAB31949.1.
FFPZ01000001 Genomic DNA. Translation: CXE23769.1.
FGBR01000001 Genomic DNA. Translation: CXL53598.1.
FJMW01000001 Genomic DNA. Translation: CZQ26127.1.
LRQH01000064 Genomic DNA. Translation: KXA38200.1.
LXNN01000103 Genomic DNA. Translation: OAF73571.1.
LWAL01000011 Genomic DNA. Translation: OAP80256.1.
PIRiB36242.
RefSeqiWP_001041272.1. NZ_LYXH01000003.1.
YP_499262.1. NC_007795.1.

Genome annotation databases

EnsemblBacteriaiAIL57194; AIL57194; CH51_03645.
CFF98212; CFF98212; ERS093009_00190.
COX86363; COX86363; ERS195423_00684.
CPB27649; CPB27649; ERS092844_00207.
CUC42598; CUC42598; ERS365775_00627.
CUE09093; CUE09093; ERS410449_01637.
CUF04544; CUF04544; ERS411017_00657.
CUF09347; CUF09347; ERS411009_00656.
KLN12184; KLN12184; RL02_07365.
GeneIDi28379010.
3921007.
KEGGisao:SAOUHSC_00703.
sauf:X998_0743.
PATRICi19578946. VBIStaAur99865_0633.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S74031 Genomic DNA. Translation: AAB31949.1.
FFPZ01000001 Genomic DNA. Translation: CXE23769.1.
FGBR01000001 Genomic DNA. Translation: CXL53598.1.
FJMW01000001 Genomic DNA. Translation: CZQ26127.1.
LRQH01000064 Genomic DNA. Translation: KXA38200.1.
LXNN01000103 Genomic DNA. Translation: OAF73571.1.
LWAL01000011 Genomic DNA. Translation: OAP80256.1.
PIRiB36242.
RefSeqiWP_001041272.1. NZ_LYXH01000003.1.
YP_499262.1. NC_007795.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi93062.SACOL0754.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIL57194; AIL57194; CH51_03645.
CFF98212; CFF98212; ERS093009_00190.
COX86363; COX86363; ERS195423_00684.
CPB27649; CPB27649; ERS092844_00207.
CUC42598; CUC42598; ERS365775_00627.
CUE09093; CUE09093; ERS410449_01637.
CUF04544; CUF04544; ERS411017_00657.
CUF09347; CUF09347; ERS411009_00656.
KLN12184; KLN12184; RL02_07365.
GeneIDi28379010.
3921007.
KEGGisao:SAOUHSC_00703.
sauf:X998_0743.
PATRICi19578946. VBIStaAur99865_0633.

Phylogenomic databases

eggNOGiENOG4105DP8. Bacteria.
ENOG410XQPT. LUCA.
KOiK19576.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
IPR004734. Multidrug-R.
IPR001958. Tet-R_TetA/multi-R_MdtG.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
PRINTSiPR01035. TCRTETA.
SUPFAMiSSF103473. SSF103473. 1 hit.
TIGRFAMsiTIGR00880. 2_A_01_02. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53459_STAAU
AccessioniPrimary (citable) accession number: Q53459
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: November 2, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.