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Protein
Submitted name:

Alkaline serine protease II

Gene

aprII

Organism
Alteromonas
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protease, Serine proteaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Alkaline serine protease IIImported
Gene namesi
Name:aprIIImported
OrganismiAlteromonasImported
Taxonomic identifieri226 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesAlteromonadaceae

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 621599Sequence analysisPRO_5004248700Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ53401.
SMRiQ53401. Positions 123-400.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 11478Inhibitor_I9InterPro annotationAdd
BLAST
Domaini152 – 379228Peptidase S8InterPro annotationAdd
BLAST
Domaini431 – 49767PPCInterPro annotationAdd
BLAST
Domaini543 – 60765PPCInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the peptidase S8 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Gene3Di3.30.70.80. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR007280. Peptidase_C_arc/bac.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Propept_inh.
IPR010259. S8pro/Inhibitor_I9.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF05922. Inhibitor_I9. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF04151. PPC. 2 hits.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q53401-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKLSAISFA VLAGLTSVNA QAAKILSVES NKAIDDQYIV VFTTPSVLNV
60 70 80 90 100
KDSKAVAAFA NKQAKALQNK HNVSITKEFG GVLNGVVINA SAKQLKGLLN
110 120 130 140 150
NPNIDYIEQD QVVTVTPAIT ASGDQANPTW GLDRVDQRNL PLNSNYHYDF
160 170 180 190 200
DGTGVTAYVI DTGVRISHNE FGNRASHGYD FVDNDNDATD CNGHGTHVAG
210 220 230 240 250
TIGGGEYGVA KNVNIVGVRV LGCNGSGSYS GVISGIDWVK NNASGPSVAN
260 270 280 290 300
MSLGGGVSQA VDDAVNNAVA SGVSFVVAAG NDNSNACNYS PARAANAITV
310 320 330 340 350
GSTTSSDARS SFSNYGNCLD IYAPGSSITS AWYNSDTSTN TISGTSMAAP
360 370 380 390 400
HVAGAVALYL DENPSLSPSQ IDSLLSQRSS KGKVSNPQSG SPNELLYTLA
410 420 430 440 450
DGTEPDPDPE PITELVNGQG VSASGASGQQ TFYKLVVPAG ASALNFSLAG
460 470 480 490 500
GTGDADLYVQ QGSQPTLNSY ACRPYLDGNN ESCDFTNPTA GDWYVMLNGY
510 520 530 540 550
AAYANATLTG TYSSDPGGCG SNCLENGIPV SGLAGASGQE LQYTIDVPAN
560 570 580 590 600
VTLTVASSGG SGDADLYVRK GAAPTTSTYD CRPFLNGNNE SCSLSSGQGA
610 620
TYYIKLRGYS SFSGVTLVAS Y
Length:621
Mass (Da):63,962
Last modified:November 1, 1996 - v1
Checksum:i8904AF8555A13BAF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S68495 Genomic DNA. Translation: AAC60459.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S68495 Genomic DNA. Translation: AAC60459.1.

3D structure databases

ProteinModelPortaliQ53401.
SMRiQ53401. Positions 123-400.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.70.80. 1 hit.
3.40.50.200. 1 hit.
InterProiIPR007280. Peptidase_C_arc/bac.
IPR000209. Peptidase_S8/S53_dom.
IPR023827. Peptidase_S8_Asp-AS.
IPR022398. Peptidase_S8_His-AS.
IPR023828. Peptidase_S8_Ser-AS.
IPR015500. Peptidase_S8_subtilisin-rel.
IPR009020. Propept_inh.
IPR010259. S8pro/Inhibitor_I9.
[Graphical view]
PANTHERiPTHR10795. PTHR10795. 1 hit.
PfamiPF05922. Inhibitor_I9. 1 hit.
PF00082. Peptidase_S8. 1 hit.
PF04151. PPC. 2 hits.
[Graphical view]
PRINTSiPR00723. SUBTILISIN.
SUPFAMiSSF52743. SSF52743. 1 hit.
SSF54897. SSF54897. 1 hit.
PROSITEiPS00136. SUBTILASE_ASP. 1 hit.
PS00137. SUBTILASE_HIS. 1 hit.
PS00138. SUBTILASE_SER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ53401_9ALTE
AccessioniPrimary (citable) accession number: Q53401
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.