Q53217 (Y4VI_RHISN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized short-chain type dehydrogenase/reductase y4vI
EC=1.-.-.-

Gene names

Ordered Locus Names:	NGR_a01150
ORF Names:	y4vI

Encoded on

Plasmid sym pNGR234a

Organism

Rhizobium sp. (strain NGR234) [Complete proteome] [HAMAP]

Taxonomic identifier

394 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Sinorhizobium fredii group › Rhizobium fredii

Protein attributes

Sequence length	548 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Domain	Contains two SDR domains.
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Sequence caution	The sequence CAA92424.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Domain	Repeat
Molecular function	Oxidoreductase
Technical term	Complete proteome Multifunctional enzyme Plasmid
Gene Ontology (GO)
Molecular_function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 548	548	Uncharacterized short-chain type dehydrogenase/reductase y4vI		PRO_0000054889
Regions
	Nucleotide binding	12 – 37	26	NAD or NADP By similarity
	Nucleotide binding	280 – 304	25	NAD or NADP By similarity
	Region	1 – 250	250	Short-chain dehydrogenase/reductase 1
	Region	271 – 548	278	Short-chain dehydrogenase/reductase 2
Sites
	Active site	154	1	Proton acceptor By similarity
	Active site	420	1	Proton acceptor By similarity
	Binding site	141	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q53217 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: 399598C5DF17C23F	FASTA	548	57,594
	10 20 30 40 50 60 MDDRQVQPGR VIVVTGAAGG IGRALVDIFA ANGDVVVAVD LPDSGVIELG QNLGEPHLGL 70 80 90 100 110 120 EVDVSREDDV VALRALLEKR FSRIEVLVNN AGIGPTMAAT ADTALEDFQR ALAINLVGAY 130 140 150 160 170 180 SVACETAKLM KPGAAIVNVA SLAGLLGNPK RSAYAASKAG LISITKSLAC RWASRGIRVT 190 200 210 220 230 240 AVAPGHVRTP MVAELERAGK LDVSAIRRRV PLGRIARPDE IARAVRFLAS AQASYITGST 250 260 270 280 290 300 LVVDGGWMSV NQPGGAHQAQ DRTPGAEFMR PVEDTDARTV IVMGGATGVG AAIARRFAEN 310 320 330 340 350 360 GDTVVIADGD GEEAVKLAGL LGDKHLSRRV DRTVETEVVS LFEELRERFG HLDVFVNGMN 370 380 390 400 410 420 EILVPNTEES PEVLKRILDV NLTGAFTCVR EAAISMRSGS VILNLGASLS LSPLAPSHAY 430 440 450 460 470 480 GAYNAGIDML TRCTAAELGP LGIRTATVAP GYIRTCAANR LAAVAGMDSA SLRQRIPLGR 490 500 510 520 530 540 VGDAEEVAEA AYFLASFDAS YINGSILHVD GGLISSREAG WGSEVDGAIS AEMRPQRRPA ARWRLLSP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequencing the 500-kb GC-rich symbiotic replicon of Rhizobium sp. NGR234 using dye terminators and a thermostable 'sequenase': a beginning." Freiberg C., Perret X., Broughton W.J., Rosenthal A. Genome Res. 6:590-600(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Molecular basis of symbiosis between Rhizobium and legumes." Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X. Nature 387:394-401(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NGR234.
[3]	"Rhizobium sp. strain NGR234 possesses a remarkable number of secretion systems." Schmeisser C., Liesegang H., Krysciak D., Bakkou N., Le Quere A., Wollherr A., Heinemeyer I., Morgenstern B., Pommerening-Roeser A., Flores M., Palacios R., Brenner S., Gottschalk G., Schmitz R.A., Broughton W.J., Perret X., Strittmatter A.W., Streit W.R. Appl. Environ. Microbiol. 75:4035-4045(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NGR234.

Cross-references

Sequence databases
EMBL GenBank DDBJ	Z68203 Genomic DNA. Translation: CAA92424.1. Different initiation. U00090 Genomic DNA. Translation: AAB91897.1.
RefSeq	NP_444110.1. NC_000914.2.
3D structure databases
ProteinModelPortal	Q53217.
ModBase	Search...
Protein-protein interaction databases
STRING	394.NGR_a01150.
Proteomic databases
PRIDE	Q53217.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAB91897; AAB91897; NGR_a01150.
GeneID	962233.
KEGG	rhi:NGR_a01150.
PATRIC	32300929. VBIRhiSp122450_0100.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1028.
HOGENOM	HOG000087667.
OMA	CEWASAG.
ProtClustDB	PRK06484.
Family and domain databases
Gene3D	3.40.50.720. 2 hits.
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR020904. Sc_DH/Rdtase_CS. [Graphical view]
PRINTS	PR00081. GDHRDH. PR00080. SDRFAMILY.
PROSITE	PS00061. ADH_SHORT. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y4VI_RHISN

Accession

Primary (citable) accession number: Q53217

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 1, 2013
This is version 73 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program