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Q53199

- DHE3_RHISN

UniProt

Q53199 - DHE3_RHISN

Protein

Probable glutamate dehydrogenase

Gene

NGR_a01340

Organism
Rhizobium sp. (strain NGR234)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 79 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei86 – 861By similarity

    GO - Molecular functioni

    1. glutamate dehydrogenase [NAD(P)+] activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular amino acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-5511-MONOMER.
    RETL1328306-WGS:GSTH-6401-MONOMER.
    RETL1328306-WGS:GSTH-6459-MONOMER.
    SFRE394:GBYN-6185-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable glutamate dehydrogenase (EC:1.4.1.3)
    Short name:
    GDH
    Gene namesi
    Ordered Locus Names:NGR_a01340
    ORF Names:y4uF
    Encoded oniPlasmid sym pNGR234a0 Publication
    OrganismiRhizobium sp. (strain NGR234)
    Taxonomic identifieri394 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeSinorhizobium/Ensifer groupSinorhizobium
    ProteomesiUP000001054: Plasmid sym pNGR234a

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 443443Probable glutamate dehydrogenasePRO_0000182753Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi394.NGR_a01340.

    Structurei

    3D structure databases

    ProteinModelPortaliQ53199.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0334.
    HOGENOMiHOG000243801.
    KOiK00261.
    OMAiELEHITR.
    OrthoDBiEOG65XN4D.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000185. Glu_DH. 1 hit.
    PRINTSiPR00082. GLFDHDRGNASE.
    SMARTiSM00839. ELFV_dehydrog. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q53199-1 [UniParc]FASTAAdd to Basket

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    MSFLDLPEGL PERIIQCNSP YTVRFGVRLR GRMYSFIGWR SVREHCEPVK    50
    GDIRYASNAD AEEVEALAAL MTLKCSLVDV PFGGSKGALK IDPRGWTPQE 100
    LEHITRRFTQ EMNKRPDRAR RQCVGSDIGT GEREMAWMMD EFRRANPTDV 150
    VTSGACVTGK PLSKGGIAGR AESTGRGVQF AIQSSLRDTR TPGLDGRRNL 200
    KGASTVIQGF GNVGYHAARF LSEEDDARVT VLAERDGYVA NPEGLSIEAL 250
    KQHQIRTGSI LGFDGAKSIA GDMCGVEQPC DVLIPAAMEN AIHAENAERM 300
    KAHLVVEAAN GPVTFEADEI LRSRGVTILP DLYVNAGGVV VSYFERVKNL 350
    THIPFGLMER RRRERGNHTI ATALERMTGK ESPADMRDEF LEGGAEIDLV 400
    RSGLEDVMRS TWTRIADLME QQPELGDYRT AAYVASIRQV ADL 443
    Length:443
    Mass (Da):48,845
    Last modified:November 1, 1996 - v1
    Checksum:i3D61C9122A9523BE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z68203 Genomic DNA. Translation: CAA92406.1.
    U00090 Genomic DNA. Translation: AAB91878.1.
    RefSeqiNP_444091.1. NC_000914.2.

    Genome annotation databases

    EnsemblBacteriaiAAB91878; AAB91878; NGR_a01340.
    GeneIDi962463.
    KEGGirhi:NGR_a01340.
    PATRICi32300963. VBIRhiSp122450_0117.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z68203 Genomic DNA. Translation: CAA92406.1 .
    U00090 Genomic DNA. Translation: AAB91878.1 .
    RefSeqi NP_444091.1. NC_000914.2.

    3D structure databases

    ProteinModelPortali Q53199.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 394.NGR_a01340.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAB91878 ; AAB91878 ; NGR_a01340 .
    GeneIDi 962463.
    KEGGi rhi:NGR_a01340.
    PATRICi 32300963. VBIRhiSp122450_0117.

    Phylogenomic databases

    eggNOGi COG0334.
    HOGENOMi HOG000243801.
    KOi K00261.
    OMAi ELEHITR.
    OrthoDBi EOG65XN4D.

    Enzyme and pathway databases

    BioCyci RETL1328306-WGS:GSTH-5511-MONOMER.
    RETL1328306-WGS:GSTH-6401-MONOMER.
    RETL1328306-WGS:GSTH-6459-MONOMER.
    SFRE394:GBYN-6185-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000185. Glu_DH. 1 hit.
    PRINTSi PR00082. GLFDHDRGNASE.
    SMARTi SM00839. ELFV_dehydrog. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequencing the 500-kb GC-rich symbiotic replicon of Rhizobium sp. NGR234 using dye terminators and a thermostable 'sequenase': a beginning."
      Freiberg C., Perret X., Broughton W.J., Rosenthal A.
      Genome Res. 6:590-600(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Molecular basis of symbiosis between Rhizobium and legumes."
      Freiberg C.A., Fellay R., Bairoch A., Broughton W.J., Rosenthal A., Perret X.
      Nature 387:394-401(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NGR234.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: NGR234.

    Entry informationi

    Entry nameiDHE3_RHISN
    AccessioniPrimary (citable) accession number: Q53199
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 79 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Plasmid, Reference proteome

    Documents

    1. Rhizobium plasmid pNGR234a
      Rhizobium plasmid pNGR234a: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3